Informatics and Analytics

2024

Kelly CT, Atkinson H, Williams D, Dharod A, Witek L, Glass C. POCUS Champion Pathway: Innovative Training Structure Supporting the Ultrasound Curriculum of a large Internal Medicine Residency Program. Health Professions Education Institute (HPEI). Winston-Salem, NC. May 2024

Stern S, Obermiller C, Witek L, Rigdon J, Moses A, Chebrolu S, Anderson M, Xiao T, Richardson K, Cristiano J, Lippert W. Updating Residency Note Templates to Reduce Documentation Burden. American Medical Informatics Association (AMIA) Clinical Informatics Conference (CIC). Minneapolis, MN. May 2024.

Ellis M, Witek L, Obermiller C, Bundy R, Moses A, Dharod A, Thorne N, Hernandez S, Denizard-Thompson, N. Implementing High-Value Care with Ambulatory Costs Transparency (ACT): Improving Provider Awareness of Orders Expenses. North Carolina User Group Meeting (NC UGM). Greensboro, NC. March 2024.

Stern S, Obermiller C, Witek L, Rigdon J, Moses A, Chebrolu S, Anderson M, Xiao T, Richardson K, Cristiano J, Lippert W. Optimizing Internal Medicine Residency Documentation: Aligning Note Templates with CMS Guidelines for Enhanced Efficiency and Resident Satisfaction. North Carolina User Group Meeting (NC UGM). Greensboro, NC. March 2024.

2023

Kelly CT, Francis B, Witek L, Glass C. Embedding Structured Ultrasound Simulator Sessions into Residency Point-of-Care Ultrasound Training. World Congress on Ultrasound in Medical Education. Detroit, Michigan. September 2023

Kelly CT, Atkinson H, Williams D, Dharod A, Witek L, Glass C. POCUS Champion Pathway: Innovative Residency Training that Supports a large Internal Medicine Residency Program’s POCUS Curriculum. World Congress on Ultrasound in Medical Education. Detroit, MI. September 2023.

Gehris J, Witek L, Bundy R, Obermiller C, Moses A, Brown P, Sutfin E, Kelly C, Dharod A, and Norton D. Quantifying Smoking Cessations Interventions and Smoking Related Screening in the Primary Care Setting. The American College of Chest Physicians (CHEST) Annual Meeting. Honolulu, Hawai’i. October 2023.

Eisner A, Witek L, Palakshappa J; Development and Validation of a Prediction Model for Cognitive Impairment in Older Adults Following Critical Illness. North Carolina Thoracic Society (NCTS). Asheville, NC. May 2023.

Eisner A, Witek L, Palakshappa J; Development and Validation of a Prediction Model for Cognitive Impairment in Older Adults Following Critical Illness. American Thoracic Society (ATS). Washington, DC. May 2023.

Moses A, Bundy R, Dharod A, Witek L, Herring K, Liu C, Maffei V, Lippert W, Stern S; Right on Time - Designing a Tool in the Electronic Health Record to Help Residents Better Anticipate Direct Admissions. North Carolina User Group Meeting (NC UGM). Greensboro, NC. February 2023.

2022

Skipina T, Bundy R, Rajendran S, Topaloglu U, Moses A, Dharod A, Barnes E; Development and Validation of a Natural Language Processing Algorithm to Identify Persons Who Inject Drugs. American Medical Informatics Association (AMIA) Clinical Informatics Conference (CIC). Houston, TX. May 2022.

Kelly CT. POCUS Champion Pathway: An Innovative Residency Training Pathway. Academic Internal Medicine Week. Charlotte, NC. April 2022

2021

George T, Hernandez S, Dharod A, Bundy R, Williams D; Harnessing the Patient Portal
to Provide Voter Resources During the COVID19 Pandemic: Was It Helpful to Patients? North Carolina Medical Society (NCMS) LEAD Conference. Virtual. October 2021.

Kelly CT; Point-of-Care Ultrasound Basics and Introduction to Cardiac, IVC, and Lung POCUS. Update on Hospital Medicine. Hilton Head, SC. October 2021.

Dharod A; mPATH™: A Digital Health Navigator. International conference on Intelligent Systems for Molecular Biology (ISMB) and European Conference on Computational Biology (ECCB). Virtual. July 2021.

2020

Weaver KE, Sutfin E, Dressler E, Bellinger C, Miller DP, Chiles C, Petty WJ, Lesser G, Foley KL; Rural/urban and race differences in factors related to cessation readiness
among cigarette smokers presenting for lung cancer screening in community settings. 13th American Association for Cancer Research (AACR) Conference. Virtual. October 2020.

Zgodic A, Zahnd WE, Miller DP, Studts JL, Eberth JM; Adjustment of Complex Survey Design Weights for Multilevel Modeling: An Application Using Optional BRFSS Modules on Lung Cancer Screening. American Public Health Association Annual Meeting. San Francisco, CA. October 2020.

Dharod A, Miller DP; Empowering Patients and Improving Preventive Care with Digital Health. CHESS Accountable Care Organization (ACO) Move to Value (MTV) Sumitt. Virtual. October 2020.

2019

2024

Bundy R, Moses A, Stambaugh E, Stewart P, Witek L, Carlasare L, Rosenthal G, Sinsky C, & Dharod A (2024). Assessment of EHR Efficiency Tools and Resources Associated with Physician Time Spent on the Inbox. Journal of General Internal Medicine. https://doi.org/10.1007/s11606-024-08761-3

Gorris MA, Needham ML, Finnegan KC, Obermiller CS, Witek L, Randle RW, & Burns CA (2024). Multidisciplinary Endocrine Tumor Board: Assessment of the Patient Experience. Journal of Patient Experience, 11, 23743735241229384. https://doi.org/10.1177/23743735241229383

2023

Birken SA, Matulewicz R, Pathak R, Wagi CR, Peluso AG, Bundy R, Witek L, Krol B, Parchman ML, Nielsen M, & Dharod A (2023). Toward the Deimplementation of Computed Tomography Urogram for Patients With Low- to Intermediate-risk Microscopic Hematuria: A Mixed-method Study of Factors Influencing Continued Use. Urology Practice, 101097UPJ0000000000000429. https://doi.org/10.1097/UPJ.0000000000000429

Gabbard J, Strahley AE, Pajewski NM, Callahan KE, Foley KL, Brown A, Moses A, Kirkendall E, Williamson JD, Brooten J, Marterre B, & Sutfin EL. (2023). Development of an Advance Care Planning Portal-Based Tool for Community-Dwelling Persons Living With Cognitive Impairment: The ACPVoice Tool. The American journal of hospice & palliative care, 40(8), 881–893. https://doi.org/10.1177/10499091221134030

Chen J, Cutrona SL, Dharod A., Bunch SC, Foley KL, Ostasiewski B, Hale ER, Bridges A, Moses A, Donny EC, Sutfin EL, Houston TK, & iDAPT Implementation Science Center for Cancer Control. (2023). Monitoring the Implementation of Tobacco Cessation Support Tools: Using Novel Electronic Health Record Activity Metrics. JMIR Medical Informatics, 11, e43097. https://doi.org/10.2196/43097

2022

Casacchia NJ, Rosenthal GE, O’Connell NS, Bundy R, Witek L, Wells BJ, & Palakshappa D (2022). Characteristics of adult primary care patients who use the patient portal: A cross-sectional analysis. Applied Clinical Informatics.13(5), 1053–1062. https://doi.org/10.1055/a-1951-3153

Valente, J., Bundy, R., Martin, M., Palakshappa, D., Dharod, A., Rominger, R., & Feiereisel, K. (n.d.). Evaluation of “Care Plus,” A Multidisciplinary Program to Improve Population Health for Patients With High Utilization. Journal of Public Health Management and Practice, 10.1097/PHH.0000000000001692. https://doi.org/10.1097/PHH.0000000000001692

Rudnick, S. R., Ugwuegbu, J., Soufleris, S. J., Bundy, R., Dharod, A., & Russo, M. W. (2022). Telephone-Only Visits Preserved Hepatocellular Cancer Screening Rates in Patients with Cirrhosis Early in the COVID-19 Pandemic. Digestive Diseases and Sciences, 1–6. https://doi.org/10.1007/s10620-022-07786-0

Lucioni, T., Hines, C., Witek, L., & Rejeski, J. (2022). Inequities in rates of variceal screening examinations. Bulletin of the National Research Centre, 46(1), 253. https://doi.org/10.1186/s42269-022-00941-7

Puccinelli-Ortega, N., Cromo, M., Foley, K. L., Dignan, M. B., Dharod, A., Snavely, A. C., & Miller, D. P. (2022). Facilitators and Barriers to Implementing a Digital Informed Decision Making Tool in Primary Care: A Qualitative Study. Applied Clinical Informatics, 13(1), 1–9. https://doi.org/10.1055/s-0041-1740481

Sheehan KN, Kelly CT. The Use of Point-of-Care Ultrasound in Acute Kidney Injuries. Open Journal of Internal Medicine 2022;12:1–12. doi:10.4236/ojim.2022.121001

Taxter, A., Frenkel, M., Witek, L., Bundy, R., Kirkendall, E., Miller, D. P., & Dharod, A. (2022). Design, Implementation, Utilization, and Sustainability of a Fast Healthcare Interoperability Resources-Based Inpatient Rounding List. Applied Clinical Informatics, 13(1), 180–188. https://doi.org/10.1055/s-0041-1742219

2021

Blok, A. C., Amante, D. J., Hogan, T. P., Sadasivam, R. S., Shimada, S. L., Woods, S., Nazi, K. M., & Houston, T. K. (2021). Impact of Patient Access to Online VA Notes on Healthcare Utilization and Clinician Documentation: A Retrospective Cohort Study. Journal of General Internal Medicine, 36(3), 592–599. https://doi.org/10.1007/s11606-020-06304-0

Brunetti, R., Zitelny, E., Newman, N., Bundy, R., Singleton, M. J., Dowell, J., Dharod, A., & Bhave, P. D. (2021). New-onset atrial fibrillation incidence and associated outcomes in the medical intensive care unit. Pacing and Clinical Electrophysiology: PACE, 44(8), 1380–1386. https://doi.org/10.1111/pace.14301

Choi J, Kelly CT, Luk FC. Stay Still’s for POCUS: using bedside ultrasound to screen for cardiac complications. Oxf Med Case Reports 2021;2021:omab055. doi:10.1093/omcr/omab055

Dutta, A., Hari, K. J., Azizian, J., Masmoudi, Y., Khalid, F., Kowal, J. L., Ahmad, M. I., Majeed, M., Macdonald, L., Sunkara, P., & Qureshi, W. T. (2021). Incidence, Predictors, and Prognosis of Acute Kidney Injury Among Cardiac Arrest Survivors. Journal of Intensive Care Medicine, 36(5), 550–556. https://doi.org/10.1177/0885066620911353

Faro, J. M., Nagawa, C. S., Orvek, E. A., Smith, B. M., Blok, A. C., Houston, T. K., Kamberi, A., Allison, J. J., Person, S. D., & Sadasivam, R. S. (2021). Comparing recruitment strategies for a digital smoking cessation intervention: Technology-assisted peer recruitment, social media, ResearchMatch, and smokefree.gov. Contemporary Clinical Trials, 103, 106314. https://doi.org/10.1016/j.cct.2021.106314

Jackson, G. L., Cutrona, S. L., White, B. S., Reardon, C. M., Orvek, E., Nevedal, A. L., Lindquist, J., Gifford, A. L., White, L., King, H. A., DeLaughter, K., Houston, T. K., Henderson, B., Vega, R., Kilbourne, A. M., & Damschroder, L. J. (2021). Merging Implementation Practice and Science to Scale Up Promising Practices: The Veterans Health Administration (VHA) Diffusion of Excellence (DoE) Program. Joint Commission Journal on Quality and Patient Safety, 47(4), 217–227. https://doi.org/10.1016/j.jcjq.2020.11.014

Kohn, M. S., Topaloglu, U., Kirkendall, E. S., Dharod, A., Wells, B. J., & Gurcan, M. (2021). Creating learning health systems and the emerging role of biomedical informatics. Learning Health Systems, 6(1), e10259. https://doi.org/10.1002/lrh2.10259

Koscielniak, N. J., Dharod, A., Moses, A., Bundy, R., Feiereisel, K. B., Albertini, L. W., & Palakshappa, D. (2021). Feasibility of computerized clinical decision support for pediatric to adult care transitions for patients with special healthcare needs. JAMIA Open, 4(4), ooab088. https://academic.oup.com/jamiaopen/article/4/4/ooab088/6420110

Nagawa, C. S., Palakshappa, J. A., Sadasivam, R. S., & Houston, T. K. (2021). Herbal or Dietary Supplement Use and Hypertensive Medications: Does the Combination Relate to Medication Adherence and Blood Pressure Control? Journal of Alternative and Complementary Medicine (New York, N.Y.), 27(2), 168–175. https://doi.org/10.1089/acm.2020.0254

Orenstein, E. W., Kandaswamy, S., Muthu, N., Chaparro, J. D., Hagedorn, P. A., Dziorny, A. C., Moses, A., Hernandez, S., Khan, A., Huth, H. B., Beus, J. M., & Kirkendall, E. S. (2021). Alert burden in pediatric hospitals: A cross-sectional analysis of six academic pediatric health systems using novel metrics. Journal of the American Medical Informatics Association: JAMIA, 28(12), 2654–2660. https://academic.oup.com/jamia/article-abstract/28/12/2654/6401984?redirectedFrom=fulltext

Palakshappa, D., Benefield, A. J., Furgurson, K. F., Harley, M. G., Bundy, R., Moses, A., Taxter, A. J., Bensinger, A. S., Cao, X., Denizard-Thompson, N., Rosenthal, G. E., & Miller, D. P. (2021). Feasibility of Mobile Technology to Identify and Address Patients’ Unmet Social Needs in a Primary Care Clinic. Population Health Management, 24(3), 385–392. https://doi.org/10.1089/pop.2020.0059

Palakshappa, D., Ip, E. H., Berkowitz, S. A., Bertoni, A. G., Foley, K. L., Miller, D. P., Vitolins, M. Z., & Rosenthal, G. E. (2021). Pathways by Which Food Insecurity Is Associated With Atherosclerotic Cardiovascular Disease Risk. Journal of the American Heart Association, 10(22), e021901. https://www.ahajournals.org/doi/10.1161/JAHA.121.021901

Skipina TM, Petty SA, Kelly CT. A near miss: subclinical saddle pulmonary embolism diagnosed by handheld ultrasound. Oxf Med Case Reports 2021;2021:omab011. doi:10.1093/omcr/omab011

Sunkara, P. R., Lippert, W. C., Rosenthal, G. E., Hiestand, B. C., Blalock, J., & Huang, C. C. (2021). Implementing a Second-Level Observation Unit at a Large Academic Medical Center. Southern Medical Journal, 114(5), 322–325. https://doi.org/10.14423/SMJ.0000000000001241

Usoh, C. O., Johnson, C. P., Speiser, J. L., Bundy, R., Dharod, A., & Aloi, J. A. (2021). Real-World Efficacy of the Hybrid Closed-Loop System. Journal of Diabetes Science and Technology, 1932296820985103. https://doi.org/10.1177/1932296820985103

2020

Amante, D. J., Blok, A. C., Nagawa, C. S., Wijesundara, J. G., Allison, J. J., Person, S. D., Morley, J., Conigliaro, J., Mattocks, K. M., Garber, L., Houston, T. K., & Sadasivam, R. S. (2020). The “Take a Break” game: Randomized trial protocol for a technology-assisted brief abstinence experience designed to engage lower-motivated smokers. Contemporary Clinical Trials, 93, 106002. https://doi.org/10.1016/j.cct.2020.106002

Arcury, T. A., Sandberg, J. C., Melius, K. P., Quandt, S. A., Leng, X., Latulipe, C., Miller, D. P., Smith, D. A., & Bertoni, A. G. (2020). Older Adult Internet Use and eHealth Literacy. Journal of Applied Gerontology: The Official Journal of the Southern Gerontological Society, 39(2), 141–150. https://doi.org/10.1177/0733464818807468

Barot, H. R., Chevli, P. A., Dutta, A., Sunkara, P., Nadella, G. S., Barot, H., Islam, T., Beekman, D., Majeed, C. N., Chaudhary, D., & Huang, C.-C. (2020). Abstract 17068: Do Post-Operative Nitrates Increase Mortality in Non-Cardiac Surgery Patients with Perioperative Myocardial Injury? Circulation, 142(Suppl_3), A17068–A17068.
https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.17068

Brooks, A. K., Miller, D. P., Fanning, J. T., Suftin, E. L., Reid, M. C., Wells, B. J., Leng, X., & Hurley, R. W. (2020). A Pain eHealth Platform for Engaging Obese, Older Adults with Chronic Low Back Pain in Nonpharmacological Pain Treatments: Protocol for a Pilot Feasibility Study. JMIR Research Protocols, 9(1), e14525. https://doi.org/10.2196/14525

Brower, H. H., Nicklas, B. J., Nader, M. A., Trost, L. M., & Miller, D. P. (2020). Creating effective academic research teams: Two tools borrowed from business practice. Journal of Clinical and Translational Science, 5(1), e74. https://doi.org/10.1017/cts.2020.553

Chen, J., Sadasivam, R., Blok, A. C., Ritchie, C. S., Nagawa, C., Orvek, E., Patel, K., & Houston, T. K. (2020). The Association Between Patient-reported Clinical Factors and 30-day Acute Care Utilization in Chronic Heart Failure. Medical Care, 58(4), 336–343. https://journals.lww.com/lww-medicalcare/fulltext/2020/04000/the_association_between_patient_reported_clinical.7.aspx

Denizard-Thompson, N. M., Miller, D. P., Snavely, A. C., Spangler, J. G., Case, L. D., & Weaver, K. E. (2020). Effect of a Digital Health Intervention on Decreasing Barriers and Increasing Facilitators for Colorectal Cancer Screening in Vulnerable Patients. Cancer Epidemiology, Biomarkers & Prevention: A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 29(8), 1564–1569. https://aacrjournals.org/cebp/article/29/8/1564/72434/Effect-of-a-Digital-Health-Intervention-on

Dharod, A., Bundy, R., Russell, G. B., Rice, W. Y., Golightly, C. E., Rosenthal, G. E., & Freedman, B. I. (2020). Primary care referrals to nephrology in patients with advanced kidney disease. The American Journal of Managed Care, 26(11), 468–474. https://doi.org/10.37765/ajmc.2020.88526

Etingen, B., Amante, D. J., Martinez, R. N., Smith, B. M., Shimada, S. L., Richardson, L., Patterson, A., Houston, T. K., Frisbee, K. L., & Hogan, T. P. (2020). Supporting the Implementation of Connected Care Technologies in the Veterans Health Administration: Cross-Sectional Survey Findings from the Veterans Engagement with Technology Collaborative (VET-C) Cohort. Journal of Participatory Medicine, 12(3), e21214. https://doi.org/10.2196/21214

Faro, J. M., Arem, H., Heston, A.-H., Hohman, K. H., Hodge, H., Wang, B., Lemon, S. C., Houston, T. K., & Sadasivam, R. S. (2020). A longitudinal implementation evaluation of a physical activity program for cancer survivors: LIVESTRONG® at the YMCA. Implementation Science Communications, 1, 63. https://doi.org/10.1186/s43058-020-00051-3

Faro, J. M., Nagawa, C. S., Allison, J. A., Lemon, S. C., Mazor, K. M., Houston, T. K., & Sadasivam, R. S. (2020). Comparison of a Collective Intelligence Tailored Messaging System on Smoking Cessation Between African American and White People Who Smoke: Quasi-Experimental Design. JMIR MHealth and UHealth, 8(4), e18064. https://doi.org/10.2196/18064

Foley, K. L., Miller, D. P., Weaver, K., Sutfin, E. L., Petty, W. J., Bellinger, C., Spangler, J., Stone, R. J., Lawler, D., Davis, W., Dressler, E., Lesser, G., & Chiles, C. (2020). The OaSiS trial: A hybrid type II, national cluster randomized trial to implement smoking cessation during CT screening for lung cancer. Contemporary Clinical Trials, 91, 105963. https://doi.org/10.1016/j.cct.2020.105963

Foley, K. L., Song, E. Y., Pockey, J., Jones, C., Spangler, J. G., Miller, D. P., Davis, W. D., & Sutfin, E. L. (2020). A pilot study to implement and sustain the US PHS clinical practice guidelines for treating tobacco use and dependence in free clinics, a safety net care setting for the uninsured. Journal of Smoking Cessation, 15(1), 14–22. https://doi.org/10.1017/jsc.2019.21

Gabbard, J., Pajewski, N., Callahan, K., Dharod, A., Foley, K., Ferris, K., Moses, A., & Williamson, J. (2020). Integrated Multidisciplinary Approach to Advance Care Planning for Vulnerable Older Adult within an Accountable Care Organization. Journal of the American Geriatric Society, 68, S5.

Jogu, H. R., Chevli, P. A., Islam, T., Dutta, A., Sunkara, P., Nadella, G. S., Barot, H., Thazhathuveetil-Kunhahamed, L.-A., & Huang, C.-C. (2020). Abstract 17039: Angiotensin Converting Enzyme Inhibitors/ Angiotensin Receptor Blockers Decrease Short-Term Mortality in Myocardial Injury After Noncardiac Surgery. Circulation, 142(Suppl_3), A17039–A17039. https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.17039

Jogu, H. R., Chevli, P. A., Nadella, G. S., Islam, T. S., Dutta, A., Sunkara, P., Barot, H., Thazhatuveetil-Kunhahamed, L.-A., Huang, C.-C., & Beekman, D. (2020). Abstract 17389: Antiplatelets Agents Decreases 30-days Mortality in Myocardial Injury After Noncardiac Surgery. Circulation, 142(Suppl_3), A17389–A17389. https://www.ahajournals.org/doi/10.1161/circ.142.suppl_3.17389

Latulipe, C., Mazumder, S. F., Wilson, R. K. W., Talton, J. W., Bertoni, A. G., Quandt, S. A., Arcury, T. A., & Miller, D. P., Jr. (2020). Security and Privacy Risks Associated With Adult Patient Portal Accounts in US Hospitals. JAMA Internal Medicine, 180(6), 845–849. https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2764648

Moore, J. B., Dilley, J. R., Singletary, C. R., Skelton, J. A., Miller, D. P., Heboyan, V., De Leo, G., Turner-McGrievy, G., McGrievy, M., & Ip, E. H. (2020). A Clinical Trial to Increase Self-Monitoring of Physical Activity and Eating Behaviors Among Adolescents: Protocol for the ImPACT Feasibility Study. JMIR Research Protocols, 9(6), e18098. https://doi.org/10.2196/18098

Moses, A., Dharod, A., Williamson, J., Pajewski, N. M., Tuerff, D., Guo, J., & Gabbard, J. (2020). Considerations for Integrating Advance Care Planning Into the Electronic Health Record: A Primer for Clinicians. The American Journal of Hospice & Palliative Care, 37(12), 1004–1008. https://doi.org/10.1177/1049909120909303

Nagawa, C. S., Emidio, O. M., Lapane, K. L., Houston, T. K., Barton, B. A., Faro, J. M., Blok, A. C., Orvek, E. A., Cutrona, S. L., Smith, B. M., Allison, J. J., & Sadasivam, R. S. (2020). Teamwork for smoking cessation: Which smoker was willing to engage their partner? Results from a cross-sectional study. BMC Research Notes, 13(1), 344. https://doi.org/10.1186/s13104-020-05183-2

Nasim, J., Ohl, C., Hernandez, S., Williamson, J., Beardsley, J., Johnson, J., Bischoff, W., Stone, T., & Luther, V. (2020). A Self-Reflection Stewardship Workshop Improves Resident Physician Understanding of Ambulatory Antibiotic Stewardship. Infection Control & Hospital Epidemiology, 41(S1), s103–s103. https://doi.org/10.1017/ice.2020.605

Palakshappa, D., Miller, D. P., & Rosenthal, G. E. (2020). Advancing the learning health system by incorporating social determinants. The American Journal of Managed Care, 26(1), e4–e6. https://doi.org/10.37765/ajmc.2020.42146

Patel, N., Miller, D. P., Snavely, A. C., Bellinger, C., Foley, K. L., Case, D., McDonald, M. L., Masmoudi, Y. R., & Dharod, A. (2020). A Comparison of Smoking History in the Electronic Health Record With Self-Report. American Journal of Preventive Medicine, 58(4), 591–595. https://doi.org/10.1016/j.amepre.2019.10.020

Shimada, S. L., Zocchi, M. S., Hogan, T. P., Kertesz, S. G., Rotondi, A. J., Butler, J. M., Knight, S. J., DeLaughter, K., Kleinberg, F., Nicklas, J., Nazi, K. M., & Houston, T. K. (2020). Impact of Patient-Clinical Team Secure Messaging on Communication Patterns and Patient Experience: Randomized Encouragement Design Trial. Journal of Medical Internet Research, 22(11), e22307. https://doi.org/10.2196/22307

Sunkara, P., Lippert, F., & Morris, C. (2020). Doing things right vs. Doing the right things A framework for a COVID-19 Person Under Investigation unit. https://www.the-hospitalist.org/hospitalist/article/220661/infectious-diseases/doing-things-right-vs-doing-right-things

Sunkara, P. R., Islam, T., Bose, A., Rosenthal, G. E., Chevli, P., Jogu, H., Tk, L. A., Huang, C.-C., Chaudhary, D., Beekman, D., Dutta, A., Menon, S., & Speiser, J. L. (2020). Impact of structured interdisciplinary bedside rounding on patient outcomes at a large academic health centre. BMJ Quality & Safety, 29(7), 569–575. https://doi.org/10.1136/bmjqs-2019-009936

Zgodic, A., Zahnd, W. E., Miller, D. P., Studts, J. L., & Eberth, J. M. (2020). Predictors of Lung Cancer Screening Utilization in a Population-Based Survey. Journal of the American College of Radiology: JACR, 17(12), 1591–1601. https://doi.org/10.1016/j.jacr.2020.06.015

2019

Bellinger, C., Pinsky, P., Foley, K., Case, D., Dharod, A., & Miller, D. (2019a). Lung Cancer Screening Benefits and Harms Stratified by Patient Risk: Information to Improve Patient Decision Aids. Annals of the American Thoracic Society, 16(4), 512–514. https://doi.org/10.1513/AnnalsATS.201810-690RL

Bensinger, A., Wilson, F., Green, P., Bloomfeld, R., & Dharod, A. (2019). Sustained Improvement in Inflammatory Bowel Disease Quality Measures Using an Electronic Health Record Intervention. Applied Clinical Informatics, 10(5), 918–926. https://doi.org/10.1055/s-0039-3400293

Blok, A. C., Sadasivam, R. S., Amante, D. J., Kamberi, A., Flahive, J., Morley, J., Conigliaro, J., & Houston, T. K. (2019). Gamification to Motivate the Unmotivated Smoker: The “Take a Break” Digital Health Intervention. Games for Health Journal, 8(4), 275–284. https://doi.org/10.1089/g4h.2018.0076

Blok, A. C., Sadasivam, R. S., Hogan, T. P., Patterson, A., Day, N., & Houston, T. K. (2019). Nurse-Driven mHealth Implementation Using the Technology Inpatient Program for Smokers (TIPS): Mixed Methods Study. JMIR MHealth and UHealth, 7(10), e14331. https://doi.org/10.2196/14331

Chevli, P. A., Jogu, H. R., Islam, T., Dutta, A., Sunkara, P., Ameen, R. B., & Huang, C.-C. (2019). Abstract 11511: Impact of Post-discharge Angiotensin-converting Enzyme Inhibitors/Angiotensin Receptor Blockers on Mortality in Patients With Asymptomatic Troponin Elevation in the Perioperative Period. Circulation, 140(Suppl_1), A11511–A11511. https://www.ahajournals.org/doi/abs/10.1161/circ.140.suppl_1.11511

Dharod, A., Atkinson, H., & Rosenthal, G. (2019). The CSI (Clinical Scholars in Informatics): A Novel Internal Medicine (IM) Resident-Driven Applied Informatics Pathway. Journal of General Internal Medicine, 34(2 Suppl), S852.

Dharod, A., Bellinger, C., Foley, K., Case, L. D., & Miller, D. (2019). The Reach and Feasibility of an Interactive Lung Cancer Screening Decision Aid Delivered by Patient Portal. Applied Clinical Informatics, 10(1), 19–27. https://doi.org/10.1055/s-0038-1676807

Dharod, A., Wells, B. J., Lenoir, K., Willeford, W. G., Milks, M. W., & Atkinson, H. H. (2019). Holiday Discharges Are Associated with Higher 30-Day General Internal Medicine Hospital Readmissions at an Academic Medical Center. Southern Medical Journal, 112(6), 338–343. https://doi.org/10.14423/SMJ.0000000000000989

Faro, J. M., Orvek, E. A., Blok, A. C., Nagawa, C. S., McDonald, A. J., Seward, G., Houston, T. K., Kamberi, A., Allison, J. J., Person, S. D., Smith, B. M., Brady, K., Grosowsky, T., Jacobsen, L. L., Paine, J., Welch, J. M., & Sadasivam, R. S. (2019). Dissemination and Effectiveness of the Peer Marketing and Messaging of a Web-Assisted Tobacco Intervention: Protocol for a Hybrid Effectiveness Trial. JMIR Research Protocols, 8(7), e14814. https://doi.org/10.2196/14814

Gabbard, J., Pajewski, N. M., Callahan, K. E., Dharod, A., Foley, K., Ferris, K., Moses, A., Grey, C., & Williamson, J. (2019). Advance care planning for vulnerable older adults within an Accountable Care Organization: Study protocol for the IMPACT randomised controlled trial. BMJ Open, 9(12), e032732. https://doi.org/10.1136/bmjopen-2019-032732

Ha, D. A., Tran, O. M., Nguyen, H. L., Nguyen, H. T., Dao, A. M., Nguyen, H. V., Vu, N. C., Chiriboga, G., Goldberg, R. J., Houston, T. K., & Allison, J. J. (2019). Stakeholder Engagement in Late-Stage Translation Phase 4 Research for Noncommunicable Diseases in Low- and Middle-Income Countries: What Works and Why-The Vietnam Experience (UMMS-Vietnam Team). Global Heart, 14(2), 143–147. https://doi.org/10.1016/j.gheart.2019.05.003

Houston, T. K., Richardson, L. M., & Cotten, S. R. (2019). Patient-directed Digital Health Technologies: Is Implementation Outpacing Evidence? Medical Care, 57(2), 95–97. https://journals.lww.com/lww-medicalcare/fulltext/2019/02000/patient_directed_digital_health_technologies__is.1.aspx

Jogu, H. R., Arora, S., Vaduganathan, M., Qamar, A., Pandey, A., Chevli, P. A., Pansuriya, T. H., Ahmad, M. I., Dutta, A., Sunkara, P. R., Qureshi, W., Vasu, S., Upadhya, B., Bhatt, D. L., Januzzi, J. L., & Herrington, D. (2019). Wake Forest University long-term follow-up of type 2 myocardial infarction: The Wake-Up T2MI Registry. Clinical Cardiology, 42(6), 592–604. https://doi.org/10.1002/clc.23182

Kuhlman, P. D., Miller, D. P., Feiereisel, K. B., Denizard-Thompson, N., & Dharod, A. (2019). A Personalized Sequential Intervention Reduces the No-Show Rate in an Academic Internal Medicine Clinic. Wake Forest Journal of Science and Medicine, 4(1), 51–55.

Shenouda, S., Dutta, A., Jogu, H., Brock, J., Ahmad, I., Chevli, P. A., Sunkara, P., Islam, T., & Huang, C.-C. (2019). Abstract 15000: Survival Effect of Beta-Blockers in Patients with Asymptomatic Perioperative Troponin Elevation. Circulation, 140(Suppl_1), A15000–A15000. https://www.ahajournals.org/doi/abs/10.1161/circ.140.suppl_1.15000

Stephens, S. E., Foley, K. L., Miller, D. P., & Bellinger, C. R. (2019). The Effects of Health Disparities on Perceptions About Lung Cancer Screening (LCS): Survey Results of a Patient Sample. Lung, 197(6), 735–740. https://doi.org/10.1007/s00408-019-00281-w

Yakovchenko, V., Hogan, T. P., Houston, T. K., Richardson, L., Lipschitz, J., Petrakis, B. A., Gillespie, C., & McInnes, D. K. (2019). Automated Text Messaging With Patients in Department of Veterans Affairs Specialty Clinics: Cluster Randomized Trial. Journal of Medical Internet Research, 21(8), e14750. https://doi.org/10.2196/14750

2018

Abel, E. A., Shimada, S. L., Wang, K., Ramsey, C., Skanderson, M., Erdos, J., Godleski, L., Houston, T. K., & Brandt, C. A. (2018). Dual Use of a Patient Portal and Clinical Video Telehealth by Veterans with Mental Health Diagnoses: Retrospective, Cross-Sectional Analysis. Journal of Medical Internet Research, 20(11), e11350. https://doi.org/10.2196/11350

Bonnecaze, A. K., Wilson, M. W., Dharod, A., Fletcher, A., & Miller, P. J. (2018). Acute kidney injury is common with intravenous abuse of extended-release oral oxymorphone and delayed renal recovery rates are associated with increased KDIGO staging. Nephrology (Carlton, Vic.), 23(10), 921–926. https://doi.org/10.1111/nep.13153

Chen, J., Druhl, E., Polepalli Ramesh, B., Houston, T. K., Brandt, C. A., Zulman, D. M., Vimalananda, V. G., Malkani, S., & Yu, H. (2018). A Natural Language Processing System That Links Medical Terms in Electronic Health Record Notes to Lay Definitions: System Development Using Physician Reviews. Journal of Medical Internet Research, 20(1), e26. https://doi.org/10.2196/jmir.8669

Chevli, P. A., Ahmad, M. I., Jogu, H. R., Dutta, A., Anees, M. A., Sunkara, P. R., & Aladin, A. I. (2018). Electrocardiographic subclinical myocardial injury and alcohol consumption: A cross-sectional analysis of data from the Third National Health and Nutrition Examination Survey. American Journal of Cardiovascular Disease, 8(5), 58–65.

Goodwin, B. C., Ford, D. E., Hsiung, R. C., Houston, T. K., Fogel, J., & Van Voorhees, B. W. (2018). First, Do No Harm: Referring Primary Care Patients with Depression to an Internet Support Group. Telemedicine Journal and E-Health: The Official Journal of the American Telemedicine Association, 24(1), 37–44. https://doi.org/10.1089/tmj.2017.0004

Hafeez, Z., Ohar, J., Ahmad, M. I., Zeeshan, A., Sunkara, P. R., Marupudi, S., Usman, S., & Malik, A. (2018). Ochrobactrum Anthropi Pneumonia: A Rare Cause of Acute Respiratory Distress Syndrome (ARDS). In C54. CRITICAL CARE CASE REPORTS: CAUSES AND COMPLICATIONS OF ACUTE RESPIRATORY FAILURE (Vol. 1–308, pp. A5332–A5332). American Thoracic Society. https://www.atsjournals.org/doi/abs/10.1164/ajrccm-conference.2018.197.1_MeetingAbstracts.A5332

Hogan, T. P., Luger, T. M., Volkman, J. E., Rocheleau, M., Mueller, N., Barker, A. M., Nazi, K. M., Houston, T. K., & Bokhour, B. G. (2018). Patient Centeredness in Electronic Communication: Evaluation of Patient-to-Health Care Team Secure Messaging. Journal of Medical Internet Research, 20(3), e82. https://doi.org/10.2196/jmir.8801

Latulipe, C., Quandt, S. A., Melius, K. A., Bertoni, A., Miller, D. P., Smith, D., & Arcury, T. A. (2018). Insights into Older Adult Patient Concerns Around the Caregiver Proxy Portal Use: Qualitative Interview Study. Journal of Medical Internet Research, 20(11), e10524. https://doi.org/10.2196/10524

McDonald, M. L., Masmoudi, Y., Patel, N., Taxter, A., Frenkel, M., Miller, D. P., & Dharod, A. (2018). A WHIRL-wind innovation: Revolutionizing inpatient rounding with the WHIRL. Journal of General Internal Medicine, 33(2 Suppl), S757.

Miller, D. P., Denizard-Thompson, N., Weaver, K. E., Case, L. D., Troyer, J. L., Spangler, J. G., Lawler, D., & Pignone, M. P. (2018). Effect of a Digital Health Intervention on Receipt of Colorectal Cancer Screening in Vulnerable Patients: A Randomized Controlled Trial. Annals of Internal Medicine, 168(8), 550–557. https://doi.org/10.7326/M17-2315

Paudel, I., Hernandez, S. M., Portalatin, G. M., Chambers, T. P., & Chambers, J. W. (2018). Sab concentrations indicate chemotherapeutic susceptibility in ovarian cancer cell lines. The Biochemical Journal, 475(21), 3471–3492. https://portlandpress.com/biochemj/article-abstract/475/21/3471/49929/Sab-concentrations-indicate-chemotherapeutic?redirectedFrom=fulltext

Pinsky, P. F., Bellinger, C. R., & Miller, D. P. (2018). False-positive screens and lung cancer risk in the National Lung Screening Trial: Implications for shared decision-making. Journal of Medical Screening, 25(2), 110–112. https://doi.org/10.1177/0969141317727771

Williams, J. H., DeLaughter, K., Volkman, J. E., Sadasivam, R. S., Ray, M. N., Gilbert, G. H., Houston, T. K., & QUIT-PRIMO and National Dental PBRN Collaborative Groups. (2018). Exploring Online Asynchronous Counseling With Tobacco Treatment Specialists in the QUIT-PRIMO and National Dental PBRN HI-QUIT Studies: Who Uses It and What Do They Say? American Journal of Health Promotion: AJHP, 32(5), 1170–1177. https://doi.org/10.1177/0890117116670972

2017

Arcury, T. A., Quandt, S. A., Sandberg, J. C., Miller, D. P., Latulipe, C., Leng, X., Talton, J. W., Melius, K. P., Smith, A., & Bertoni, A. G. (2017). Patient Portal Utilization Among Ethnically perse Low-Income Older Adults: Observational Study. JMIR Medical Informatics, 5(4), e47. https://doi.org/10.2196/medinform.8026

Blok, A. C., May, C. N., Sadasivam, R. S., & Houston, T. K. (2017). Virtual Patient Technology: Engaging Primary Care in Quality Improvement Innovations. JMIR Medical Education, 3(1), e3. https://doi.org/10.2196/mededu.7042

Cutrona, S. L., Fouayzi, H., Burns, L., Sadasivam, R. S., Mazor, K. M., Gurwitz, J. H., Garber, L., Sundaresan, D., Houston, T. K., & Field, T. S. (2017). Primary Care Providers’ Opening of Time-Sensitive Alerts Sent to Commercial Electronic Health Record InBaskets. Journal of General Internal Medicine, 32(11), 1210–1219. https://doi.org/10.1007/s11606-017-4146-3

Fitch, D. N., Dharod, A., Campos, C. L., & Núñez, M. (2017). Use of electronic health record clinical decision support tool for HCV birth cohort screening. Journal of Viral Hepatitis, 24(11), 1076. https://doi.org/10.1111/jvh.12729

Greene, M., Johnson, J. A., Seale, J. P., Tindol, A., Le, K. B., Clemow, D. D., Barham, A. H., & Miller, D. P. (2017). The prevalence of binge drinking among primary care residents. Substance Abuse, 38(3), 292–296. https://doi.org/10.1080/08897077.2016.1212778

Houston, T. K., Fix, G. M., Shimada, S. L., Long, J. A., Gordon, H. S., Pope, C., Volkman, J., Allison, J. J., DeLaughter, K., Orner, M., & Bokhour, B. G. (2017). African American Veterans Storytelling: A Multisite Randomized Trial to Improve Hypertension. Medical Care, 55 Suppl 9 Suppl 2, S50–S58. https://journals.lww.com/lww-medicalcare/fulltext/2017/09001/african_american_veterans_storytelling__a.11.aspx

Jogu, H. R., Chevli, P. A., Bose, A., Vasireddy, A., Sompalli, S., Gopireddy, G. A. R., Dutta, A., Maludum, O., Yarra, P., Amjad, A., Menon, S., Sunkara, P. R., & Qureshi, W. T. (2017). Abstract 451: Beta Blocker Use in Asymptomatic Patients with Sepsis and Elevated Troponin is Associated with Lower Risk of Mortality. Circulation Research, 121(suppl_1), A451–A451. https://www.ahajournals.org/doi/10.1161/res.121.suppl_1.451

Lycan, T., Hansen, K., & Miller, D. P. (2017). Impact of Curriculum Content on Resident Attitudes Towards Cancer Care. Journal of Cancer Education: The Official Journal of the American Association for Cancer Education, 32(2), 280–282. https://doi.org/10.1007/s13187-015-0908-y

McInnes, D. K., Shimada, S. L., Midboe, A. M., Nazi, K. M., Zhao, S., Wu, J., Garvey, C. M., & Houston, T. K. (2017). Patient Use of Electronic Prescription Refill and Secure Messaging and Its Association with Undetectable HIV Viral Load: A Retrospective Cohort Study. Journal of Medical Internet Research, 19(2), e34. https://doi.org/10.2196/jmir.6932

Miller, D. P., Weaver, K. E., Case, L. D., Babcock, D., Lawler, D., Denizard-Thompson, N., Pignone, M. P., & Spangler, J. G. (2017). Usability of a Novel Mobile Health iPad App by Vulnerable Populations. JMIR MHealth and UHealth, 5(4), e43. https://doi.org/10.2196/mhealth.7268

Wilson, F., Bloomfeld, R., Green, P., & Dharod, A. (2017). Quality Measures in Outpatient Inflammatory Bowel Disease Care: Are We Documenting Compliance? [Published abstract]. Inflammatory Bowl Diseases, 23, S50–S51.

Wilson, M. W., Bonnecaze, A. K., Dharod, A., & Miller, P. J. (2017). Analysis of Intensive Care Unit Admission and Sequelae in Patients Intravenously Abusing Extended-Release Oral Oxymorphone. Southern Medical Journal, 110(3), 217–222. https://doi.org/10.14423/SMJ.0000000000000624

Woods, S. S., Forsberg, C. W., Schwartz, E. C., Nazi, K. M., Hibbard, J. H., Houston, T. K., & Gerrity, M. (2017). The Association of Patient Factors, Digital Access, and Online Behavior on Sustained Patient Portal Use: A Prospective Cohort of Enrolled Users. Journal of Medical Internet Research, 19(10), e345. https://doi.org/10.2196/jmir.7895

July 2021 – June 2022
Wake Forest Clinical and Translational Science Institute
Principal Investigator: Sarah Birken
Collaborator: Richa Bundy

CTSI Microscopic Hematuria Study

Our study aims to thoroughly understand low-value care in microscopic hematuria patients by quantifying its prevalence and assess determinants. Develop evidence-based strategies using advanced implementation mapping methods to reduce unnecessary CT scans for low- and intermediate-risk patients, promoting high-value care. Evaluate strategy feasibility, acceptability, and appropriateness through targeted user interviews with primary care and urology clinicians, administrators, and stakeholders.

2021
WFBMI Pilot Funding
Co-Investigator: Ajay Dharod
Collaborators: Richa Bundy, Lauren Witek

Evaluating racial disparities in continued prostate cancer screening in older men with very low serum prostate specific antigen levels

The objective of the work is to characterize current prostate cancer screening patterns in men over age 70 at Atrium Health and Atrium Health Wake Forest within the OMOP Common Data Model. This project will provide a methodologic example for integrations of Atrium Health and Atrium Health Wake Forest clinical data for research leveraging the OMOP CDM while providing preliminary data for future grant applications focused on interventions to decrease prostate cancer screening in elderly men with low serum PSA throughout the Atrium Health and Atrium Health Wake Forest enterprise.

May 2020 – May 2021
Wake Forest Center for Precision Medicine
Principal Investigator: Sean Hernandez
Collaborators: Ajay Dharod, Adam Moses and Richa Bundy

Use of Whole Genome Sequencing in Familial Colorectal Cancers

This pilot grant seeks to specifically further evaluate the results from current targeted sequencing that is performed in patients referred to Genetic Counseling after being identified as high risk for familial colorectal cancer and test the hypothesis that whole genome sequencing can replicate the results of targeted genetic testing panels in patients with known pathogenic variants consistent with colorectal cancer.

March 2016 – February 2017
Wake Forest Clinical and Translational Sciences Institute/Wake Forest Comprehensive Cancer Center (Joint Award)
Principal Investigator: Dave Miller
Co-Investigator: Ajay Dharod

Development and Pilot Testing of a Clinical Informatics Lung Cancer Screening Intervention

This pilot study developed and tested a novel population health intervention for lung cancer screening. The intervention was delivered via Wake Forest Baptist Health’s patient portal, determines patient’s eligibility for lung cancer screening, and includes a personalized screening decision aid. I created and validated the EHR query, determined patient portal messaging workflows, analyzed data and disseminated results.

September 2023 – August 2028
Agency for Healthcare Research and Quality
Co-investigator: Dave Miller

This project will develop and implement a digital clinical decision support tool to assist rural paramedics at the point-of-care with evidence-based STEMI care.

August 2023 – July 2028
National Cancer Institute
Site Principal Investigator: Dave Miller
Co-investigator: Ajay Dharod

Evaluating a Remotely Delivered, Digital Health CRC Screening Intervention among Racially Diverse Patients of a Community Health Center

This project will determine the effectiveness and optimal way to implement the mPATH-Cloud digital health platform as fully remote and culturally responsive strategy for increasing CRC screening among low-income, rural and racially diverse patients.

July 2023 – December 2024
PCORI Health Systems Implementation Initiative
Principal Investigators: Kristie Foley and Kevin High
Collaborators: Lauren Witek, Ajay Dharod, Richa Bundy, Adam Moses

To increase infrastructure, skills, and capacity for implementation practice and program evaluation in preparation for the PCORI Health Systems Implementation Initiative evidence-based practice projects.

July 2023 – June 2024
American Medical Association (AMA) EHR Use Grant
Co-investigator: Ajay Dharod & Corey Obermiller
Collaborators: Lauren Witek, Richa Bundy, Adam Moses

Exploring Primary Care Physician Time Spent in EHR During Time Away from Work

This research will ascertain administrative paid time off (PTO) data for full-time and part-time primary care clinicians and quantify total time spent in the EHR (including time spent in documentation and time spent in in-basket activities) in the days leading up to, during, and following PTO dates. Furthermore, we will describe PTO EHR use by provider attributes such as specialty, academic versus community, sex, age, and panel complexity.

April 2023 – March 2026
National Cancer Institute
Site Principal Investigator: Anna Snavely
Collaborators: Richa Bundy

A cloud-based digital health navigation program for colorectal cancer screening

This STTR project will establish the feasibility, effectiveness, and value of a cloud-based digital health navigation program (mPATH™) that helps patients get screened for colorectal cancer, the second leading cause of cancer death in the United States.

July 2022 – June 2023
American Medical Association (AMA) EHR Use Grant
Coinvestigators: Ajay Dharod & Richa Bundy
Collaborators: Adam Moses, Paschal Stewart, Elisabeth Stambaugh, Gary Rosenthal

Exploring physician time in the EHR inbox and tools aimed at optimizing inbox efficiency.

This study involved developing and validating a normalized measure of provider time in the inbox using EHR user action log and provider schedule data. This research also sought to identify inbox related activities that contribute to the most burden in terms of time and volume of messages. Finally, this study explored the association between clinic staffing resources and provider use of EHR efficiency tools and provider inbox time. 

September 2022 – August 2027
National Cancer Institute
Principal Investigator: Tom Houston
Collaborators: Corey Obermiller

Using Rural Community Paramedicine to Engage Lower-Motivated Smokers: Spreading an Effective mHealth-Assisted Intervention to Motivate Cessation

We will conduct a multi-level "hybrid type 2" study (i.e.: implementation and effectiveness outcomes) to test 1) a novel implementation program in rural counties and 2) a mHealth (mobile health)-assisted brief abstinence experience (Take a Break, TAB) for rural adults who smoke and are not-yet-ready to quit. In our network of rural counties, the implementation trial will use a novel, multi-strategy implementation program centered on county employees engaged in `community paramedicine.' In this field, most trials have focused only on those already ready-to-quit. Thus, the proposed trial addresses an important knowledge gap critical to advance tobacco control in rural areas.

September 2021 – January 2022
National Cancer Institute
Co-Investigator: Dave Miller

ATLAS: Alleviating Lung Cancer Disparities through Cancer Control (Cancer Center Support Grant Supplement)

The overarching goal of ATLAS is to reduce disparities in lung cancer through robust planning for a P01 application. The planning grant will provide dedicated resources for pilot data collection, strategic planning meetings, and project coordination.

July 2021 – August 2027
Duke Endowment Health Services Grant
Principal Investigator: Tom Houston
Collaborator: Corey Obermiller

Specially Trained Staff to facilitate Virtual Care for Vulnerable Patients and Family Caregivers: A real-world implementation and evaluation across North and South Carolina

The goal of this grant is to implement a “Super-Supporter” program among at-risk patients in 100 primary care, geriatrics, and specialty clinics across Western North Carolina and the greater Charlotte area. We hypothesize that, among at-risk patients, the Super-Supporter program will result in 1) higher rates of successful video visits, and 2) improved patient experience, compared with a control condition.

July 2021 – June 2024
Duke Endowment Grant
Informatics and Analytics: Dr. Padageshwar Sunkara

Hypertensive Disorders of Pregnancy (HDP)

This initiative will span from July 2021– June 2024 and will be co-led by Drs. Elizabeth Jensen and Emily Bunce with the help of a large multidisciplinary team. The project will be designed as a randomized control trial comparing remote Blood Pressure Monitoring (BPM) intervention to usual care for postpartum women, with the objective of informing postpartum care management and mitigating the risk of serious adverse, pregnancy-associated hypertensive events.

June 2021 – August 2024
National Institute on Aging
Principal Investigator: Jessica Palakshappa
Collaborator: Lauren Witek

Development and Validation of a Prediction Model for Cognitive Impairment in Older Adults Following Critical Illness

The overall objectives of this study are (1) to describe the prevalence of post-ICU cognitive impairment across a large academic health system to estimate the burden of illness, and (2) develop and validate a prediction model using electronic health record data to determine which adults may be at highest risk for post-ICU cognitive impairment. 

March 2021 – February 2022
National Institute on Aging (NIA) IMPACT Collaboratory
Co-Investigator: Dr. Ajay Dharod
Collaborators: Adam Moses and Richa Bundy

Using Telemedicine to Improve Engagement in Advance Care Planning in Patients with Cognitive Impairment or Unrecognized Dementia

This pilot study will inform and strengthen the design of a large-scale, multicenter embedded pragmatic trial. Telemedicine has the potential to overcome ACP barriers related to timing and travel restraints. It also provides patients and their caregivers with an opportunity to discuss their goals, values and priorities for healthcare within their home setting, thereby prioritizing “aging in place”. Engaging patients in ACP and obtaining appropriate reimbursement allows primary care providers to sustainably deliver high-quality, patient-centered care.

January 2021 – December 2024
National Cancer Institute
Principal Investigator: Dave Miller

A Personalized Digital Outreach Intervention for Lung Cancer Screening

This project will use a pragmatic randomized controlled trial and mixed methods to determine the impact of a digital health intervention (mPATH-Lung) on patient shared decision making and receipt of lung cancer screening.

July 2020 – June 2024
The Duke Endowment
Co-Investigator: Dr. Ajay Dharod
Collaborators: Richa Bundy and Adam Moses

WFIT Program for Recovery After Critical Illness

This trial aims to implement and evaluate a systematic approach to critical illness recovery.

July 2020 – June 2024
National Institute of Nursing Research (NINR)
Principal Investigator: Dennis Ang
Co-investigator: Ajay Dharod
Collaborator: Adam Moses and Richa Bundy

Pain Response Evaluation of a Combined Intervention to Cope Effectively (PRECICE)

The objective of this application is to conduct a 24-week randomized clinical trial of primary care patients. In the UH3 trial, 280 participants will be randomized to one of three treatments: (1) combination treatment [duloxetine + web-based CBT] with nurse support, (2) combination treatment without nurse support, and (3) duloxetine monotherapy. This project could optimize pain-related treatment outcomes by combining duloxetine and web-based CBT at the primary care level where most pain patients are managed. Importantly, the use of nurse clinician providing adherence-focused guidance to maintain long term use or practice of pain coping skills (web-based CBT) increases the likelihood that our proposed intervention is scalable.

June 2020 – May 2021
National Cancer Institute
Principal Investigator: Dave Miller
Co-Investigator: Ajay Dharod

Administrative Supplement to Effectiveness and Implementation of mPATH-CRC: a Mobile Health System for Colorectal Cancer Screening

The activities of this Administrative Supplement will translate the mPATH colorectal cancer screening iPad app to scalable and robust software infrastructure using interoperable industry standards (SMART on FHIR) and cloud computing.

April 2020 – March 2025
National Institute of Health
Co-Investigator: Tom Houston

Adapt2Quit – A Machine-Learning, Adaptive Motivational System: RCT for Socio-Economically Disadvantaged smokers

We propose testing Adapt2Quit — an innovative motivational texting “recommender system.” Adapt2Quit enhances tailored motivational messaging systems using machine-learning algorithms to learn from, and adapt to, user feedback (prior and daily message ratings), thereby increasing message personal relevance. Our study will test Adapt2Quit motivational messaging texting with socioeconomically disadvantaged (SED) smokers.

September 2019 – August 2024
National Cancer Institute
Principal Investigator: David Miller
Co-Investigator: Ajay Dharod

A Personalized Digital Outreach Intervention for Lung Cancer Screening

This project will use a pragmatic randomized controlled trial and mixed methods to determine the impact of a digital health intervention (mPATH-Lung) on patient shared decision making and receipt of lung cancer screening.

September 2019 – August 2024
National Cancer Institute
Principal Investigator: Tom Houston
Co-Investigator: Dave Miller

iDAPT – Implementation and Informatics Developing Adaptable Processes and Technologies for Cancer Control

The goal of this Developing Center grant is to advance the field of implementation science by using technologies to support rapid cycle and real time deployment and testing of implementation processes and adaptations within cancer control.

August 2019 – July 2021
National Institute of Diabetes and Digestive and Kidney Diseases
Co-Investigator: Dave Miller

IMPACT: Increased Monitoring of Physical Activity and Calories with Technology

This pilot study will determine the acceptability, feasibility, and economic costs of a tailored, mobile (mHealth) program for use in an evidence-based pediatric weight management program (Brenner FIT).

July 2019 – June 2024
National Institute of Health/National Center for Advancing Translational Sciences
Co-Investigator: Dave Miller
Faculty: Ajay Dharod

Wake Forest Clinical and Translational Science Award

This application establishes a Clinical and Translational Science Award based in the Wake Forest Translational Science Institute.

July 2019 – June 2020
Cancer Prevention and Control – Office of Cancer Health Equity
Co-Investigator: Dave Miller

Engaging stakeholders to inform the adaptation of a personalized electronic care planning tool for colorectal cancer survivors

This research will adapt an electronic tool developed for stroke care planning (COMPASS-CP) to CRC survivorship care planning. We will follow a user-centered design process to adapt COMPASS-CP CRC and include mixed-methods assessments of stakeholder feedback to plan for an implementation study.

April 2019 – March 2021
Agency for Healthcare Research and Quality
Co-Investigator: Dave Miller

Health Information Technology (IT) to Improve Health Care Quality and Outcomes

The purpose of this project is to develop and evaluate a novel direct-to-patient alert for hemoglobin A1c (HbA1c) screening. We will send text messages to patients at a high risk for elevated blood sugar as determined by a previously published HbA1c risk calculator applied to the electronic health record. The project will estimate the probability of a patient undergoing screening and explore factors that influenced patients’ screening decisions, setting the stage for a future clinical trial.

March 2019 – March 2026
AstraZeneca Pharmaceuticals LP
Principal Investigator: Barry Freedman
Collaborator: Richa Bundy and Lauren Witek

AstraZeneca APOL1 and Chronic Kidney Disease

Establish an electronic medical record (EMR)-derived database at Wake Forest Baptist Health (WFBH) consisting of all African American patients with data on kidney function to assess the rates of development and progression of chronic kidney disease (CKD) and proteinuria.

December 2018 – September 2020
Patient-Centered Outcomes Research Insitution
Co-Investigator: Tom Houston

Mid-South Clinical Data Research Network (CDRN)

The Mid-South CDRN will continue work initiated through PCORnet to develop a multi-institutional data network to support pragmatic trials and observational studies to compere the effectiveness of widely used treatments and delivery strategies and to engage patients, clinicians, and other stakeholders.

April 2018 – March 2023
National Cancer Institute
Principal Investigator: Dave Miller
Co-Investigator: Ajay Dharod

Effectiveness and Implementation of mPATH-CRC: a Mobile Health System for Colorectal Cancer Screening

This hybrid effectiveness-implementation project will: 1) evaluate the ability of an innovative iPad program (mPATH-CRC) to increase use of colorectal cancer screening, and 2) determine the optimal way to implement the program in community-based practices. This project will improve public health by increasing the use of life-saving screening tests and by identifying the key factors that inhibit or encourage the sustained use of technology-based programs in medical care.

September 2018 – August 2019
US Food and Drug Administration
Co-Investigator: Ajay Dharod

Expanding HL7 FHIR to support post-marketing research and surveillance within multi-source, chronic disease registries

Explore methods to use the HL7 FHIR standard to address information exchange needs of clinical research and post-market research and surveillance. The focus is on the development of technology for enabling utilization of Real World Data (RWD).

February 2018 – February 2020
Arthritis Foundation – Dartmouth Institute
Co-Investigator: Ajay Dharod

Rheumatology Learning Health System Pilot Site Testing

Wake Forest was one of three pediatric sites chosen to co-design, develop, and test “coproduction dashboards” for use by patients and parents and their clinicians and care teams to make informed, collaborative treatment decisions and care plans by capturing patient-reported outcomes and clinical data.

January 2018 – June 2021
The Duke Endowment
Co-Investigator: Ajay Dharod

An Integrated Approach to Patient and Family Engagement for Advance Care Planning in an Accountable Care Organization (ACO)

The goal of this project was to determine whether a nurse navigator-led ACP pathway combined with a health care professional-facing EHR interface improves the occurrence of ACP discussions and their documentation within the EHR.

August 2017 – March 2022
National Institute of Health
Co-Investigator: Tom Houston

mHealth Messaging to Motivate Quitline Use and Quitting (M2Q2): RCT in rural Vietnam

The mHealth Messaging to Motivate Quitline Use and Quitting (M2Q2) is a collaborative research project for a mobile health intervention among men and women smokers in Vietnam’s Red River Delta region. The goal of M2Q2 is to increase use of the Bach Mai quit line, increasing access to counseling services and nicotine replacement therapy, and motivate smokers with tailored messages, with the goal of promoting cessation among current tobacco users in Vietnam.

March 2017 – March 2021
Patient-Centered Outcomes Research Institute
Co-Investigator: Tom Houston

Smoker-to-Smoker Peer Marketing and Messaging to Disseminate Tobacco Intervention

Using a  2×2 factorial design, S2S will test two smoker-driven, social marketing innovations to recruit and engage smokers in Decide2Quit.org (Decide2Quit), an evidence-based, effective “Digital Intervention for Smoking Cessation” (DISC).

September 2016 – August 2021
National Cancer Institute
Co-Investigator: Dave Miller 

Implementation of Smoking Cessation Services within NCI NCORP Community Sites with Organized Lung Cancer Screening Programs

The purpose of this efficacy-implementation study is to evaluate the efficacy of a multi-faceted intervention to promote smoking cessation, to assess implementation of evidence-based tobacco cessation strategies, and to develop an implementation toolkit for non-academic, community-based LDCT lung cancer screening programs.