Message from the Co-Chairs of Research
Hospital Medicine’s research mission is to conduct and initiate clinical research that contributes to the field of hospital medicine and health care learning systems. The Hospital Medicine Research Committee aids our hospital medicine providers in all phases of a research project from start to finish:
- Help formulate a research question
- Assist with the Institutional Review Board approval process
- Help with data collection
- Formulate a statistical plan
- Perform the statistical analysis
- Assist with manuscript writing
Our research in hospital medicine is focused in several areas, including (but not limited to):
- Cardiovascular research
- Obesity and metabolism
- Learning health care systems
- Implementation and evaluation of several pilot interventions in hospital medicine settings
- High-value care
We are also involved in collaborative research within and outside the Wake Forest Baptist Health system. Our section is comprised of outstanding hospital medicine providers with innovative and creative minds, who are always thriving in the field of evidence-based medicine. Overall, our scholarly activity has increased by more than 2.5 times since our last academic year, and our hospital medicine providers continue to present their work at local, regional, national and international conferences as well as having it published in peer-reviewed journals. Our goal moving forward is to continue to increase the quantity and improve the quality of our scholarly work as well as to receive grant funding for our section.
Parag Chevli, MBBS
Assistant Professor of Internal Medicine
Co-Chair of Hospital Medicine Research
Luqman TK, MD
Assistant Professor of Internal Medicine
Co-Chair of Hospital Medicine Research
Journal Club
Under the leadership of former co-chair Dr. Tareq Islam, the Section of Hospital Medicine started its own Journal Club in January 2019. Each month, we dissect important and clinically relevant research papers and focus on their research methodology and data analysis. The goal is to stay up-to-date on any new advancements or guidelines in hospital medicine (and other fields) as well as to promote scholarly activities within our section.
Scholarly Activity, July 2018 to Present
2021
- Rangecroft A, Prabhu SS, Huang CC. Pickles and warfarin interaction: a case-based review. Clin Rheumatol. 2021 April
- Sunkara PR, Lippert WC, Rosenthal GE, Hiestand BC, Blalock J, Huang CC. Implementing a second-level observation unit at a large academic medical center. South Med J. 2021 May; 114:322-325
- Isa SO, Buhari O, Adeniran-Isa M, Khan M, Khan H, Konda R, Changezi H, Afonso L. In-hospital outcomes after percutaneous coronary interventions in cardiac allograft recipients. SAGE Open Medicine. 2021 Feb 10; 9: 2050312121993290
- Isa SO, Adegbala O, Buhari O, Khan M, Adekolujo O, Adekolujo O, Munir A, Hassan M. Impact of obstructive sleep apnea on in-hospital outcomes of patients with non-st elevation myocardial infarction. Hearts. 2021; 2(1), 119-126
2020
- Sharma S, Barot HV, Schwartzman AD, Ganatra S, Shah SP, Venesy DM, Patten RD. Risk and predictors of dyssynchrony cardiomyopathy in left bundle branch block with preserved left ventricular ejection fraction. Clin Cardiol. 2020 December;43(12):1494-1500
- Kumar P, Follen M, Huang CC, Cathey A. Using Laddering Interviews and Hierarchical Value Mapping to Gain Insights Into Improving Patient Experience in the Hospital: A Systematic Literature Review. Journal of patient experience. 2020 December;7(6):1740-1747
- Bose A, Chevli PA, Berberian G, Januszkiewicz J, Ahmad G, Hashmath Z, Mishra AK, Laidlaw D. Presence of a left common pulmonary vein and pulmonary vein anatomical characteristics as predictors of outcome following cryoballoon ablation for paroxysmal atrial fibrillation. Journal of Interventional Cardiac Electrophysiology. 2020 Nov 18. Online ahead of print
- Dutta A, Tayal B, Kragholm KH, Masmoudi Y, Azizian J, McDonald L, Goyal A, Sogaard P, Qureshi WT. Characteristics and outcomes of cardiac arrest survivors with acute pulmonary embolism. Resuscitation. 2020 October;155:6-12
- Chevli PA, Hari KJ, Kanaya AM, Talegawkar SA, Needham BL, Herrington D. Association of Alcohol Consumption and Ideal Cardiovascular Health Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. Alcoholism-Clinical and Experimental Research. 2020 Sep;44(9):1825-1833
- Kovalic AJ, Majeed CN, Samji NS, Thuluvath PJ, Satapathy SK. Systematic review with meta-analysis: abnormalities in the international normalised ratio do not correlate with periprocedural bleeding events among patients with cirrhosis. Alimentary pharmacology & therapeutics. 2020 September;52(8):1298-1310
- Jogu HR, Arora S, Strassle PD, Patel C, Patil N, Venkatesh S, Alkhaimy H, Ramm CJ, Qamar A, Kim SM, Yeung M, Vavalle JP. Impact of age and comorbidities on the effect of transcatheter versus surgical mitral valve repair on inpatient outcomes. 2020 May;95(6):1195-1201
- Chevli PA, Aladin AI, Kanaya AM, Kandula NR, Malaver D, Herrington DM. Alcohol Consumption and Subclinical Atherosclerosis Among South Asians: Findings From The Mediators Of Atherosclerosis In South Asians Living In America (Masala) Study. Nutr Metab Cardiovasc Dis. 2020 Jan 3;30(1):123-131
2019
- Sunkara PR, Islam T, Bose A, Rosenthal GE, Chevli P, Jogu H, Luqman TK, Huang CC, Chaudhary D, Beekman D, Dutta A, Menon S, Speiser JL. Impact of structured interdisciplinary bedside rounding on patient outcomes at a large academic health centre. BMJ Qual Saf. Published online: 2019 Dec 6.
- Ryan D, Lippert WC, Fenwick AJ, Bhatt M, Jones CR. Central Nervous System Blastomycosis With Multiple Brain Abscesses Presenting as Right Upper Extremity Weakness. Neurohospitalist. 2019 Oct;9(4):230-234
- Dutta A, Hari K, Qureshi W. Risk of Mortality associated with use of mechanical support devices among comatose cardiac arrest patients. European Heart Journal. 2019 Oct 21;40(1): ehz748.0465
- Ahmad MI, Singleton MJ, Bhave PD, Kamel H, Soliman EZ. Atrial Cardiopathy and stroke mortality in the general Population. Int J Stroke. 2019 Sep 17:1 747493019876543
- Ahmad MI, Majeed CN, Chadhary D, Dutta A, Jogu HR, Soliman EZ. Relation of Marital Status and QT interval Prolongation (from the Third National Health and Nutrition Examination Survey). Am J Cardiol. 2019 Jul 15;124(2):211-215
- Kowal J, Ahmad MI, Li Y, Soliman EZ. Prognostic significance of electrocardiographic right ventricular hypertrophy in general population. J Electrocardiol. 2019 May – Jun; 54:49-53
- Anees MA, Ahmad MI, Chevli PA, Li Y, Soliman EZ. Association of vitamin D deficiency with electrocardiographic markers of left atrial abnormalities. Ann Noninvasive Electrocardol. 2019 May;24(3):e12626
- Fraz MA, Warraich FH, Warraich SU, Tariq MJ, Warraich Z, Khan AY, Usman M, Ijaz A, Tenneti P, Mushtaq A, Akbar F, Shahid Z, Ali Z, Fazeel HM, Rodriguez C, Nasar A, McBride A, Anwer F. Special considerations for the treatment of multiple myeloma according to advanced age, comorbidities, frailty and organ dysfunction. Crit Rev Oncol Hematol. 2019 May;137:18-26
- Lippert WC, Chadha R, Sweigart JR. Things We Do for No Reason: The Use of Thickened Liquids in Treating Hospitalized Adult Patients with Dysphagia. J Hosp Med. 2019 May;14(5):315-317
- Lippert WC, Lee EY, Mirrakhimov AE. A woman, age 35, with new-onset ascites. Cleve Clin J Med. 2019 Apr;86(4):257-262
- Ahmad MI, Chevli PA, Barot H, Soliman EZ. Interrelationships Between American Heart Association's Life's Simple 7, ECG Silent Myocardial Infarction, and Cardiovascular Mortality. J Am Heart Assoc. 2019 Mar 19;8(6):e011648
- Ahmad MI, Dutta A, Anees MA, Soliman EZ. Interrelations between Serum Uric Acid, Silent Myocardial Infarction and Mortality in the General Population. American Journal of Cardiology. Am J Cardiol. 2019 Mar 15;123(6):882-888
- Vasim I, Ahmad MI, Mongraw-Chaffin M, Soliman EZ. Association of Obesity Phenotypes with Electrocardiographic Subclinical Myocardial Injury in the General Population." Clin Cardiol. 2019 Mar;42(3):373-378
- Treska K, Thomas S, Mills T, Hermann T, Ellis M, Huang C, Finkel N. Thirty Day Readmission Rates and Seven Day Follow Up among High Risk Patients: Interrupted Time Series Design. Journal of Science & Medicine. 2019 Spring; 4(1): 77-84
- Yeboah P, Hsu FC, Bertoni AG, Yeboah J. Body Mass Index, Change in Weight, Body Weight Variability and Outcomes in Type 2 Diabetes Mellitus (from the ACCORD Trial). Am J Cardiol. 2019 Feb 15;123(4):576-581
- Arena AL, Cao X, Hamilton BJ, Chaudhary D. Reversible cerebral vasoconstriction syndrome (RCVS) in the context of aseptic meningitis in a twenty-eight-year-old postpartum female. Case Reports in Internal Medicine. 2019 Jan 30;6(1):16-21
2018
- Chevli PA, Ahmad MI, Jogu HR, Dutta A, Anees MA, Sunkara PR, Aladin AI. Electrocardiographic subclinical myocardial injury and alcohol consumption: a cross-sectional analysis of data from the Third National Health and Nutrition Examination Survey. Am J Cardiovasc Dis. 2018 Dec 15;8(5):58-65
- Sunkara PR, Huang C, Menon S, Kumar P. Using advanced data analytics to improve Healthcare Supply Chain. Healthcare Tech Outlook Magazine. 2018 December. 40-41
- Inayat F, O’Neill SS, Zafar F, Marupudi S, Vasim I. Idiopathic hypereosinophilic syndrome with cutaneous involvement: a comparative review of 32 cases. BMJ Case Rep. 2018 Dec;11(1):bcr-2018-227137
- Ahmad MI, Li Y, Soliman EZ. Association of Obesity Phenotypes with Electrocardiographic Left Ventricular Hypertrophy in the General Population. J Electrocardiol. 2018 Nov – Dec;51(6):1125-1130
- Amjad A, Pisani B, Dutta A. Delayed Drive Line Site Soft Tissue Infection after Ventricular Assist Device Inactivation: A Case Report. Journal of Cardiac Failure. 2018 August;24(8):S85
- Berdy AE, Patel NJ, German CA, Dutta A, Pisani BA. Chylothorax as a Post-Operative Complication of Orthotopic Heart Transplantation. Journal of Cardiac Failure. 2018 August;24(8):S84
- Gaglani B, Dahdouh M, Shah K. Septic arthritis of native hip joint by Staphylococcus lugdunensis: a case report. Rev Soc Bras Med Trop. 2018 Jul-Aug;51(4):554-556.
- Vestal RA. Preoperative Evaluation of the Ophthalmology Patient. J Perioper Med. 2018;1(2): 106
2021
- Aortic stenosis but not mitral regurgitation increases mortality in cardiac amyloidosis patients. Presented at: American College of Cardiology's 70th Annual Scientific Session, May 15-17, 2021
- Igg4 related disease: A rare cause of recurrent pericardial effusion and constrictive pericarditis. Presented at: American College of Cardiology's 70th Annual Scientific Session, May 15-17, 2021
- Outcome of spontaneous coronary artery dissection in congestive heart failure patients. Presented at: American College of Cardiology's 70th Annual Scientific Session, May 15-17, 2021
- Targeted Plasma Metabolomic Profiling and Subclinical Atherosclerosis: Findings from the Diabetes Heart Study (DHS). Presented at: American College of Cardiology's 70th Annual Scientific Session, May 15-17, 2021
- The role of smoking on cryoballoon ablation outcomes for paroxysmal atrial fibrillation. Presented at: American College of Cardiology's 70th Annual Scientific Session, May 15-17, 2021
- The role of smoking on cryoballoon ablation outcomes for paroxysmal atrial fibrillation. American College of Cardiology's 70th Annual Scientific Session. Virtual May 15-17, 2021
- You can spell DRESS without the “E.” Society of Hospital Medicine Annual Conference, May 3-7, 2021
- Drug Reaction with Eosinophilia and Systemic Symptoms - A Misnomer for Making the Diagnosis. Presented at: 2021 Society of General Internal Medicine Annual Meeting, April 20-23, 2021
- Acyclovir Induced DILI: A Rare Side Effect Of A Common Medication Presented at: North Carolina ACP Conference, February 19-20, 2021
- Don’t look “PAST”eurella. Presented at: North Carolina ACP Conference, February 19-20, 2021
- Viral Pneumonia with Vesicular Rash in the Time of COVID-19. Presented at: North Carolina ACP Conference, February 19-20, 2021
- You can spell DRESS without the “E.” Presented at: North Carolina ACP Conference, February 19-20, 2021
- Prognostic Value of Troponin Levels in Cardiac Arrest Survivors. Presented at: 50th Critical Care Congress Virtual Event, January 31 - February 12, 2021
2020
- Angiotensin Converting Enzyme Inhibitors/ Angiotensin Receptor Blockers Decrease Short-term Mortality In Myocardial Injury After Noncardiac Surgery. Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- Antiplatelets Agents Decreases 30-days Mortality In Myocardial Injury After Noncardiac Surgery. Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- Can Understanding of National Search Engine Queries Inform Heart Failure Prevention? National Internet Search Engine Queries Correlates With CHF Prevalence but Not Outcomes. Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- Do Post-operative Nitrates Increase Mortality In Non-Cardiac Surgery Patients With Perioperative Myocardial Injury? Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- The Relationship Between the American Heart Association’s Life Simple 7, Ectopic Fat and Insulin Resistance Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- The Role of Obstructive Sleep Apnea in Hospitalization in Heart Failure With Preserved Ejection Fraction and Diabetes Mellitus. Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- The Role of Body Mass Index in Cryoballoon Ablation Outcomes for Paroxysmal Atrial Fibrillation. Presented at: American Heart Association Virtual Scientific Session, November 14-16, 2020
- Stuck Between the Aorta and a Hard Place: Managing SMA Syndrome in Long-Term ICU Patients. Presented at: American College of Gastroenterology Annual Meeting, October 23-28, 2020
2019
- Alcohol Consumption and Subclinical Atherosclerosis Among South Asians: Findings From The Mediators Of Atherosclerosis In South Asians Living In America (Masala) Study. Presented at: AHA Scientific Sessions 2019. November 16-18, 2019; Philadelphia, PA, USA
- APP Burnout. Presented at: 2019 Society of General Internal Medicine Meeting. May 8-11 2019; Washington, D.C., USA
- Don’t always blame CREST syndrome for the heart problems. Presented at: 2019 American College of Physicians Internal Medicine Meeting. April 11-13, 2019; Philadelphia, PA, USA
- Current trend in Obesity (1999-2016): Modifiable factors influencing current trend and possible contribution of healthcare system. Presented at: EuroSciCon Conference. April 11-12, 2019; Paris, France
- Healthcare Utilization among Obese Population: Role of Hospital Medicine. Presented at: EuroSciCon Conference. April 11-12, 2019; Paris, France
- Thyrotoxic periodic paralysis: an unusual presentation of subtle hyperthyroidism. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Teach the Teacher Model: An Innovative Method for Implementing a Point of Care Ultrasound Curriculum within a Large Academic Institution. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Right treatment - but wrong sequence: case of schmidt syndrome. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Point of Care Ultrasound Defuses a Ticking Time Bomb: Early Bedside Evaluation of Infective Endocarditis. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Patient-centered approach to health (path): outcome analysis of interdisciplinary bedside rounding. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Lightning huddle: an innovative method for improving patient throughput. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Healthcare Utilization among Obese Population: Role of Hospital Medicine. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019. National Harbor, MD, USA
- Handling hand hygiene: factors implicated in non-adherence at an academic medical center. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Current trend in Obesity (1999-2016): Modifiable factors influencing current trend and possible contribution of healthcare system. Presented at: 2019 Society of Hospital Medicine Annual Conference. March 24-27, 2019; National Harbor, MD, USA
- Impact of Subclinical Hypoglycemia on Mortality: Findings From the Third National Health and Nutrition Examination Survey. Presented at: EPI|LIFESTYLE Scientific Sessions 2019. March 5-8, 2019; Houston, TX, USA
- Stepping into the “Lymelight.” Presented at: North Carolina ACP Conference. February 22-23, 2019; Raleigh, NC, USA
- Point of Care Ultrasound Defuses a Ticking Time Bomb: Early Bedside Evaluation of Infective Endocarditis. Presented at: North Carolina ACP Conference. February 22-23, 2019; Raleigh, NC, USA
- I Refuse to Accept the Diagnosis of AKI. Presented at: North Carolina ACP Conference. February 22-23, 2019; Raleigh, NC, USA
- Impact of postoperative angiotensin-converting enzyme inhibitors/angiotensin receptor blockers on mortality and morbidity in patients with asymptomatic troponin elevation in the perioperative period. Presented at: 14th Annual Perioperative Medicine Summit. February 13-16, 2019; Orlando, FL, USA
- Billing project abstract and oral presentation at Epic Presented at: North Carolina EPIC UGM 2019. January 22-23, 2019; Greensboro, NC, USA
2018
- Hospitalist Paging Standardization: Lean Six Sigma Project to Improve Patient Safety, Interdisciplinary Communication and Satisfaction. Presented at: 30th Annual National Forum on Quality Improvement in Health Care. December 9-12, 2018; Orlando, FL, USA
- Vitamin D Deficiency and Electrocardiographic Subclinical Myocardial Injury: Results from National Health and Nutrition Examination Survey-III. Presented at: AHA Scientific Sessions 2018. November 10-14, 2018; Chicago, IL, USA
- Association between Obesity Phenotypes and Electrocardiographic Markers of Poor Outcomes. Presented at: AHA Scientific Sessions 2018. November 10-14, 2018; Chicago, IL, USA
- Association of Obesity Phenotypes with Subclinical Myocardial Injury in the General Population. Presented at: AHA Scientific Sessions 2018. November 10-14, 2018; Chicago, IL, USA
- Hypoglycemia and mortality. Presented at: AHA Scientific Sessions 2018. November 10-14, 2018; Chicago, IL, USA
- Uric acid, silent MI and mortality. Presented at: AHA Scientific Sessions 2018. November 10-14, 2018; Chicago, IL, USA
- Minor ECG abnormalities and mortality. Presented at: AHA Scientific Sessions 2018. November 10-14, 2018; Chicago, IL, USA
- Current trend in Obesity (1999-2016): Modifiable factors influencing current trend and possible contribution of healthcare system. Presented at: Obesity Medicine Association. April 4-8, 2018; San Diego, CA, USA
- Healthcare Utilization among Obese Population: Role of Hospital Medicine. Presented at: Obesity Medicine Association. April 4-8, 2018; San Diego, CA, USA
- DTNPV1 and Stroke Mortality. Presented at: ACC 2018. March 10-12, 2018; Orlando, FL, USA
- Kherlopian A, Barot H, Alsindi F, Huang C. Atrial Fibrillation. Texto de Medicina Interna by Hernando Vargas Uricoechea. Popayán. University of the Cauca. 2021
- Huang, C, Lippert, WC, Payne, B, Pariyadath, M, & Sunkara, PR. Wave, surge, or tsunami- Different COVID-19 models and predicting inpatient bed capacity. The Hospitalist. 2020, July 14
- Luqman Arafath TK, Jubbal S, Gireesh E, Margapuri J, Jogu HR, Patni H, Thompson T, Patel A, Abdulla A, Menon S, Penupolu S. Risk of Transmission of infection to Healthcare Workers delivering Supportive Care for Coronavirus Pneumonia; A Rapid GRADE Review. MedRxiv; 2020
- Jogu, HR. Myocardial Injury: An Umbrella Diagnosis of Confusion. Short Communication. Open Access Journal Of Cardiology. ISSN: 2578-4633. Volume 4 Issue 1. Feb 14, 2020
Obesity Management Collaboration
Hospital Medicine team lead is partnering with our obesity medicine colleagues at Wake Forest Baptist Health (Drs. Jamy Ard and Jessica Bartfield) on the management of obesity. This novel approach will emphasize on identifying obesity as a disease and initiating intervention while the patient is in house. It will be a multidisciplinary approach following guidelines provided by the Obesity Medicine Association. The goal is for our providers to acknowledge obesity as a disease and to recognize when to initiate a consult with obesity medicine, as well as for our patients to have a better understanding of obesity and different ways of treating it. To achieve this goal, part of the project will focus on:
- Hospitalist education on principals of management of obesity
- Appropriate patient selection
- Patient-centered early intervention with follow up
Attending Rounding Study
Dr. William Lippert and other Wake Forest Baptist general internal medicine colleagues are participating in a multi-institutional study with the University of Kentucky and University of Michigan on comparing attending rounding strategy with their resident teaching evaluations. The goal is to gain meaningful insight into resident rounding preference.
Grants
- Hospital at Home (H@H) - Duke Endowment Grant
Description: Realizing Equitable and Accessible Care through Hospital at Home Implementation and Testing (REACH-IT)
Raghava Nagaraj and Padageshwar Sunkara will be serving as Project and Research lead
- Hypertensive Disorders of Pregnancy (HDP) - Duke Endowment Grant
Description: A randomized control trial comparing remote Blood Pressure Monitoring (BPM) intervention to usual care for postpartum women
Padageshwar Sunkara will be serving as a Physician Lead in Informatics and data analytics
Awards
Parag Chevli, MBBS, won the best oral case presentation on his abstract entitled "Impact of post-operative ACEi/ARBs on mortality and morbidity in patients with asymptomatic troponin elevation in the perioperative period" at the 2019 Perioperative Medicine Summit in Orlando, Florida.
Padageshwar Sunkara, MBBS, had a publication in BMJ Quality & Safety entitled “Impact of Structured Interdisciplinary Bedside Rounding on Patient Outcomes at a Large Academic Health Centre” that was recognized as a “Top 10 Paper Published in 2019” by the Wake Forest School of Medicine’s Department of Internal Medicine.