Department of Pathology Research

Frye BM, Negrey JD, Johnson CSC, Kim J, Barcus RA, Lockhart SN, Whitlow CT, Chiou KL, Snyder-Mackler N, Montine TJ, Craft S, Shively CA, Register TC. Mediterranean diet protects against a neuroinflammatory cortical transcriptome: Associations with brain volumetrics, peripheral inflammation, social isolation, and anxiety in nonhuman primates (Macaca fascicularis). Brain Behav Immun. 2024 Jul;119:681-692. doi: 10.1016/j.bbi.2024.04.016. Epub 2024 Apr 16. PMID: 38636565.

Burks M, Warren CS, Lightfoot T, Fadeyi EA. Anti-E alloimmunization from a platelet apheresis transfusion in a 22-month-old male with acute myeloid leukemia. Lab Med. 2024 Feb 12:lmae 002. doi: 10.1093/labmed/lmae002. Epub ahead of print. PMID: 38346103.

Cox LA, Puppala S, Chan J, Zimmerman KD, Hamid Z, Ampong I, Huber HF, Li G, Jadhav AYL, Wang B, Li C, Baxter MG, Shively C, Clarke GD, Register TC, Nathanielsz PW, Olivier M. Integrated multi-omics analysis of brain aging in female nonhuman primates reveals altered signaling pathways relevant to age-related disorders. Neurobiology Aging. 2023 Dec;132:109-119. doi: 10.1016/j.neurobiolaging.2023.08.009. Epub 2023 Aug 29. PMID: 37797463; PMCID: PMC10841409.

Huber HF, Li C, Xie D, Gerow KG, Register TC, Shively CA, Cox LA, Nathanielsz PW. Female baboon adrenal zona fasciculata and zona reticularis regulatory and functional proteins decrease across the life course. Geroscience. 2024 Feb 5. doi: 10.1007/s11357-024-01080-9. Epub ahead of print. PMID: 38311700.

Scarberry SR, Prutchi H, Frye BM, Herr J, Scott C, Long CM, Jorgensen MJ, Shively CA, Kavanagh K. Development and assessment of a stair ascension challenge as a measure of aging and physical function in non-human primates. Am J Primatol. 2024 Feb;86(2):e23582. doi: 10.1002/ajp.23582. Epub 2023 Dec 5. PMID: 38050788; PMCID: PMC10843660.

Zbieranski N, Insuasti-Beltran G. Analytical Validation of an Automated Semiconductor-Based Next-Generation Sequencing Assay for Detection of DNA and RNA Alterations in Myeloid Neoplasms. J Mol Di-agn. 2024 Jan;26(1):29-36. doi:10.1016/j.jmoldx. 2023.09.011. Epub 2023 Oct 23. PMID: 37879438.

Berson E, Gajera CR, Phongpreecha T, Perna A, Bukhari SA, Becker M, Chang AL, De Francesco D, Espinosa C, Ravindra NG, Postupna N, Latimer CS, Shively CA, Register TC, Craft S, Montine KS, Fox EJ, Keene CD, Bendall SC, Aghaeepour N, Montine TJ. Cross-species comparative analysis of single presynapses. Scientific reports. 2023;13(1):13849. PMID: 37620363

Bhoopal B, Gollapelli KK, Damuka N, Miller M, Krizan I, Bansode A, Register T, Frye BM, Kim J, Mintz A, Orr M, Craft S, Whitlow C, Lockhart SN, Shively CA and Solingapuram Sai KK. Preliminary PET Imaging of Microtubule-Based PET Radioligand [(11)C]MPC-6827 in a Nonhuman Primate Model of Alzheimer's Dis-ease. ACS chemical neuroscience. 2023;14:3745-3751. PMID:37724996

Chino Y, Olson JD, Schaaf GW, Cline JM, Johnson TE. Longitudinal analysis of leukocyte total and differ-ential count of rhesus macaques (Macaca mulatta) after total body irradiation. Radiation Research. 2023 Aug 8. doi: 10.1667/RADE-23-00072.1. Epub ahead of print. PMID: 37590486.

Cox LA, Puppala S, Chan J, Zimmerman KD, Hamid Z, Ampong I, Huber HF, Li G, Jadhav AYL, Wang B, Li C, Baxter MG, Shively C, Clarke GD, Register TC, Nathanielsz PW and Olivier M. Integrated multi-omics analysis of brain aging in female nonhuman primates reveals altered signaling pathways relevant to age-related disorders. Neurobiology of aging. 2023;132:109-119. PMID:37797463

Foucar K, Bagg A, Bueso-Ramos CE, George T, Hasserjian RP, Hsi ED, Orazi A, Tam W, Wang SA, Weinberg OK, Arber DA Guide to the Diagnosis of Myeloid Neoplasms: A Bone Marrow Pathology Group Ap-proach. Am J Clin Pathol. 2023 Oct 3;160(4):365-393. doi: 10.1093/ajcp/aqad069. PMID: 3739117

Frye BM, Register TC, Appt SE, Vitolins MZ, Uberseder B, Chen H and Shively CA. Differential effects of western versus mediterranean diets and psychosocial stress on ovarian function in female monkeys (Macaca fascicularis). Psychoneuroendocrinology. 2023;153:106107. PMID: 37060654

Johnson BJ, Barcus RA, Olson JD, Lipford ME, Andrews RN, Dugan GO, Tooze JA, Kim J, Deycmar S, Whitlow CT, Cline JM. Total-body irradiation alters white matter volume and microstructural integrity in rhesus macaques. Int J Radiat Oncol Biol Phys. 2023 Nov 14:S0360-3016(23)08138-5. doi: 10.1016/j.ijrobp.2023.11.014. PMID: 37972714.

Mishra S, Kumar A, Kim S, Su Y, Singh S, Sharma M, Almousa S, Rather HA, Jain H, Lee J, Furdui CM, Ahmad S, Ferrario CM, Punzi HA, Chuang CC, Wabitsch M, Kritchevsky SB, Register TC and Deep G. A Liquid Biopsy-Based Approach to Isolate and Characterize Adipose Tissue-Derived Extracellular Vesicles from Blood. ACS Nano. 2023;17:10252-10268. PMID: 37224410

Negrey JD, Frye BM, Craft S, Register TC, Baxter MG, Jorgensen MJ and Shively CA. Executive function mediates age-related variation in social integration in female vervet monkeys (Chlorocebus sabaeus). GeroSci-ence. 2023. PMID: 37217631

Parameswaran N, Luo L, Zhang L, Chen J, DiFilippo FP, Androjna C, Fox DA, Ondrejka SL, Hsi ED, Jagadeesh D, Lindner DJ, Lin F. CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma. Leukemia. 2023 Oct;37(10):2050-2057. doi: 10.1038/s41375-023-01997-8. Epub 2023 Aug 12. PMID: 37573404

Quillen D, Hughes TM, Craft S, Howard T, Register T, Suerken C, Hawkins GA and Milligan C. Levels of Soluble Interleukin 6 Receptor and Asp358Ala Are Associated With Cognitive Performance and Alzheimer Dis-ease Biomarkers. Neurol Neuroimmunol Neuroinflamm. 2023;10. PMID: 36810164

Schaaf GW, Olson JD, Dugan GO, Pray BA, Cleary JA, Cline JM. Dose-Dependent Testicular Injury and Recovery after Total-Body Irradiation in Rhesus Monkeys. Radiat Res. 2023 Sep 13. doi: 10.1667/RADE-23-00008.1.S1. Epub ahead of print. PMID: 37702414.

Shively CA, Frye BM, Negrey JD, Johnson CSC, Sutphen CL, Molina AJA, Yadav H, Snyder-Mackler N and Register TC. The interactive effects of psychosocial stress and diet composition on health in primates. Neuro-sci Biobehav Rev. 2023;152:105320. PMID: 37453725

Tomasino AM, Olson JD, Schaaf GW, Cox AO, Furdui CM, Cline JM, Cohen EP. A New Method for Estimating Glomerular Filtration Rate in Rhesus Macaques (Macaca mulatta). Radiat Res. 2023 Oct 30. doi: 10.1667/RADE-23-00062.1. Epub ahead of print. PMID: 37902230.

Xu-Monette ZY, Li Y, Snyder T, Yu T, Lu T, Tzankov A, Visco C, Bhagat G, Qian W, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Wang Y, Go H, Ponzoni M, Ferreri AJM, Møller MB, Parsons BM, Fan X, van Krieken JH, Piris MA, Winter JN, Au Q, Kirsch I, Zhang M, Shaughnessy J, Xu B, Young KH. Tumor-Infiltrating Normal B Cells Revealed by Immunoglobulin Repertoire Clonotype Analysis Are Highly Prognostic and Cru-cial for Antitumor Immune Responses in DLBCL. Clin Cancer Res. 2023 Dec 1;29(23):4808-4821. doi: 10.1158/1078-0432.CCR-23-1554. PMID: 3772887

Chino Y, Olson JD, Schaaf GW, Cline JM, Johnson TE. Longitudinal analysis of leukocyte total and differential count of rhesus macaques (Macaca mulatta) after total body irradiation. Radiation Research. 2023 Aug 8. doi: 10.1667/RADE-23-00072.1. Epub ahead of print. PMID: 37590486.

Dotlic S, Gibson SE, Hartmann S, Hsi ED, Klimkowska M, Rodriguez-Pinilla SM, Sabattini E, Tousseyn TA, de Jong D, Dojcinov S. Lymphomas with plasmablastic features: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology. Virchows Arch. 2023 Aug 10. doi: 10.1007/s00428-023-03585-8. Online ahead of print. PMID: 37561194

Gibson SE, Docjinov S, Dotlic S, Hartmann S, Hsi ED, Klimkowska M, Melle F, Pileri SA, Ramsower CA, Rech K, Rimsza LM, Rodriguez-Pinilla SM, Tousseyn TA, de Jong D, Sabattini E. Mediastinal large B cell lymphoma and surrounding gray areas: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology. Virchows Arch. 2023 Aug 2. doi: 10.1007/s00428-023-03550-5. Online ahead of print. PMID: 37530791

Hartmann S, Dojcinov S, Dotlic S, Gibson SE, Hsi ED, Klapper W, Klimkowska M, Pinilla SMR, Richter J, Sabattini E, Tousseyn T, de Jong D. The spectrum of nodular lymphocyte predominant Hodgkin lymphoma: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology. Virchows Arch. 2023 Aug 2. doi: 10.1007/s00428-023-03554-1. Online ahead of print.PMID: 37530790.

Parameswaran N, Luo L, Zhang L, Chen J, DiFilippo FP, Androjna C, Fox DA, Ondrejka SL, Hsi ED, Jagadeesh D, Lindner DJ, Lin F. CD6-targeted antibody-drug conjugate as a new therapeutic agent for T cell lymphoma. Leukemia. 2023 Aug 12. doi: 10.1038/s41375-023-01997-8. Online ahead of print. PMID: 37573404

Rodriguez-Pinilla SM, Docjinov S, Dotlic S, Gibson SE, Hartmann S, Klimkowska M, Sabattini E, Tousseyn TA, de Jong D, Hsi ED. Aggressive B-cell non-Hodgkin lymphomas: a report of the lymphoma workshop of the 20th meeting of the European Association for Haematopathology. Virchows Arch. 2023 Aug 2. doi: 10.1007/s00428-023-03579-6. Online ahead of print.PMID: 37530792

Ruggiero AD, Vemuri R, DeStephanis D, Brock A, Block MR, Chou J, Das SK, Williams AG, Kavanagh K. Visceral adipose microbial and inflammatory signatures in metabolically healthy and unhealthy nonhuman primates. Obesity (Silver Spring). 2023 Aug 24. doi: 10.1002/oby.23870. Epub ahead of print. PMID: 37614163.

Russler-Germain DA, Krysiak K, Ramirez C, Mosior M, Watkins MP, Gomez F, Skidmore ZL, Trani L, Gao F, Geyer S, Cashen AF, Mehta-Shah N, Kahl BS, Bartlett NL, Alderuccio JP, Lossos IS, Ondrejka SL, Hsi ED, Martin P, Leonard JP, Griffith M, Griffith OL, Fehniger TA. Mutations Associated with Progression in Follicular Lymphoma Predict Inferior Outcomes at Diagnosis (Alliance A151303). Blood Adv. 2023 Jul 26:bloodadvances.2023010779. doi: 10.1182/bloodadvances.2023010779. Online ahead of print. PMID: 37493986

Vergara-Lluri M, Kovach AE, Nakashima MO, Bradley KT, Mahe E, Tsao L, Savage NM, Salansky SA, Long T, Perkins SL, Hsi ED, Pozdnyakova O, Bhargava P. Significant Variability in the Identification and Reporting of Band Neutrophils by Participants Enrolled in the College of American Pathologists Proficiency Testing Program: Time for a Change. Arch Pathol Lab Med. 2023 Aug 28. doi: 10.5858/arpa.2023-0015-CP. Online ahead of print. PMID: 37638547

Bansode AH, Damuka N, Bashetti N, Gollapelli KK, Krizan I, Bhoopal B, Miller M, Jv SK, Whitlow CT, McClain D, Ma T, Jorgensen MJ, Solingapuram Sai KK. First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations. J Med Chem. 2023 Jun 14. doi: 10.1021/acs.jmedchem.3c00720. Epub ahead of print. PMID: 37315328.

Fadeyi OA, Keresztes P, Saha AK, Fadeyi EA. Preventing transfusion-associated circulatory overload in acute care settings. Nursing. 2023 Jun 01; 53(6):37-41. PMID: 37212817

Foucar K, Bagg A, Bueso-Ramos CE, George T, Hasserjian RP, Hsi ED, Orazi A, Tam W, Wang SA, Weinberg OK, Arber DA. Guide to the Diagnosis of Myeloid Neoplasms: A Bone Marrow Pathology Group Approach. Am J Clin Pathol. 2023 Jun 30. Online ahead of print. PMID: 37391178

French MJ, Wuerker R, Dugan G, Olson JD, Sanders BR, Tooze JA, Caudell DL, Cline JM, Sempowski GD, Macintyre AN. Long-Term Immunological Consequences of Radiation Exposure in a Diverse Cohort of Rhesus Macaques. Int J Radiat Oncol Biol Phys. 2023 Mar 15;115(4):945-956. doi: 10.1016/j.ijrobp.2022.10.024. Epub 2022 Oct 23. PMID: 36288757; PMCID: PMC9974872.

Frye BM, Register TC, Appt SE, Vitolins MZ, Uberseder B, Chen H, Shively CA. Differential effects of western versus mediterranean diets and psychosocial stress on ovarian function in female monkeys (Macaca fascicularis). Psychoneuroendocrinology. 2023 Jul; 153:106107. doi: 0.1016/j.psyneuen.2023.106107. Epub 2023 Apr 5. PMID: 37060654; PMCID: PMC10225337.

Kirtek T, Chen W, Laczko D, Bagg A, Koduru P, Foucar K, Venable E, Nichols M, Rogers HJ, Tam W, Orazi A, Hsi ED, Hasserjian RP, Wang SA, Arber DA, Weinberg OK. Acute leukemias with complex karyotype show a similarly poor outcome independent of mixed, myeloid or lymphoblastic immunophenotype: A study from the Bone Marrow Pathology Group. Leuk Res. 2023 Jul; 130:107309. PMID: 37210875

Mikhailov A. Systemic lupus erythematosus. PathologyOutlines.com website. https://www.pathologyoutlines.com/topic/kidneysle.html Mishra S, Kumar A, Kim S, Su Y, Singh S, Sharma M, Almousa S, Rather HA, Jain H, Lee J, Furdui CM, Ahmad S, Ferrario CM, Punzi HA, Chuang CC, Wabitsch M, Kritchevsky SB, Register TC, Deep G. A Liquid Biopsy-Based Approach to Isolate and Characterize Adipose Tissue-Derived Extracellular Vesicles from Blood. ACS Nano. 2023 Jun 13;17(11):10252-10268. doi:10.1021/acsnano.3c00422. Epub 2023 May 24. PMID: 37224410.

Negrey JD, Frye BM, Craft S, Register TC, Baxter MG, Jorgensen MJ, Shively CA. Executive function mediates age-related variation in social integration in female vervet monkeys (Chlorocebus sabaeus). Geroscience. 2023 May 23. doi: 10.1007/s11357-023-00820-7. Epub ahead of print. PMID: 37217631

Nichols MM, Ondrejka SL, Patil S, Durkin L, Hill BT, Hsi ED. Ki67 proliferation index in follicular lymphoma is associated with favorable outcome in patients treated with R-CHOP. Leuk Lymphoma. 2023 May 24:1-9. Online ahead of print. PMID: 37226602

Ruggiero AD, Vemuri R, Blawas M, Long M, DeStephanis D, Williams AG, Chen H, Justice JN, Macauley SL, Day SM, Kavanagh K. Long-term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design. Geroscience. 2023 Jun 1. doi:10.1007/s11357-023-00830-5. Epub ahead of print. PMID: 37261678.

Schaaf GW, Justice JN, Quillen EE, Cline JM. Resilience, aging, and response to radiation exposure (RARRE) in nonhuman primates: a resource review. Geroscience. 2023 May 16. doi: 10.1007/s11357-023-00812-7. Epub ahead of print. PMID: 37188889.

Ramia de Cap M, Wu LP, Hirt C, Pihan GA, Patel SS, Tam W, Bueso-Ramos CE, Kanagal-Shamanna R, Raess PW, Siddon A, Narayanan D, Morgan EA, Pinkus GS, Mason EF, Hsi ED, Rogers HJ, Toth L, Foucar K, Hurwitz SN, Bagg A, Rets A, George TI, Orazi A, Arber DA, Hasserjian RP, Weinberg OK; Bone Marrow Pathology Group. Myeloid sarcoma with NPM1 mutation may be clinically and genetically distinct from AML with NPM1 mutation: a study from the Bone Marrow Pathology Group. Leuk Lymphoma. 2023 Mar 24:1-9. PMID: 36960680

EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential. Li Y, Xu-Monette ZY, Abramson J, Sohani AR, Bhagat G, Tzankov A, Visco C, Zhang S, Dybkaer K, Pan Z, Xu M, Tam W, Zu Y, Hsi ED, Hagemeister FB, Go H, van Krieken JH, Winter JN, Ponzoni M, Ferreri AJM, Møller MB, Piris MA, Wang Y, Zhang M, Young KH.Blood Adv. 2023 Apr 11;7(7):1308-1311. PMID: 36399513

Al-Ghamdi YA, Lake J, Bagg A, Thakral B, Wang SA, Bueso-Ramos C, Masarova L, Verstovsek S, Rogers HJ, Hsi ED, Gralewski JH, Chabot-Richards D, George TI, Rets A, Hasserjian RP, Weinberg OK, Parilla M, Arber DA, Padilla O, Orazi A, Tam W. Triple-Negative Primary Myelofibrosis: A Bone Marrow Pathology Group Study. Mod Pathol. 2023 Mar;36(3):100016. doi: 10.1016/j.modpat.2022.100016. PMID: 36788093

Cantu MD, Kanagal-Shamanna R, Wang SA, Kadia T, Bueso-Ramos CE, Patel SS, Geyer JT, Tam W, Madanat Y, Li P, George TI, Nichols MM, Rogers HJ, Liu YC, Aggarwal N, Kurzer JH, Maracaja DLV, Hsi ED, Zaiem F, Babu D, Foucar K, Laczko D, Bagg A, Orazi A, Arber DA, Hasserjian RP, Weinberg OK. Clinicopathologic and Molecular Analysis of Normal Karyotype Therapy-Related and De Novo Acute Myeloid Leukemia: A Multi-Institutional Study by the Bone Marrow Pathology Group. JCO Precis Oncol. 2023 Jan;7:e2200400. doi: 10.1200/PO.22.00400. PMID: 36689697.

Maracaja L, Khanna AK, Murphy SV, Maracaja DLV, Lane MR, Khoury O, Tan J, Damuka N, Crawford FF, Bottoms JA, Miller MD, Kaczka DW, Jordam JE, Sai KKS. Positron Emission Tomography-Computed Tomography Imaging of Selective Lobar Delivery of Stem Cells in Ex Vivo Lung Model of Mechanical Ventilation. J Aerosol Med Pulm Drug Deliv. 2023 Feb;36(1):20-26. doi: 10.1089/jamp.2022.0013. Epub 2022 Dec 30. PMID: 36594924; PMCID: PMC9942179.

Gisriel, S.D., Yuan, J., Braunberger, R.C., Maracaja, D.L.V., Chen, X., Wu, X., McCracken, J., Chen, M., Xie, Y., Brown, L.E., Li, P., Zhou, Y., Sethi, T., McHenry, A., Hauser, R.G., Paulson, N., Tang, H., Hsi, E.D., Wang, E., Zhang, Q.Y., Young, K.H., Xu, M.L., Pan, Z. Human herpesvirus 8-negative effusion-based large B-cell lymphoma: a distinct entity with unique clinicopathologic characteristics. Mod Pathol (2022). https://doi.org/10.1038/s41379-022-01091-x

Fadeyi E, Mamo YT, Saha AK, Wilson E, Pomper G. The Viability of Hematopoietic Progenitor Cell Grafts after Cryopreservation Does Not Predict Delayed Engraftment in Allogeneic Hematopoietic Stem Cell Transplantation. Lab Med. 2022 May 28:lmac042. doi: 10.1093/labmed/lmac042. Epub ahead of print. PMID: 35640044. https://doi.org/10.1093/labmed/lmac042

Kanagal-Shamanna R, Orazi A, Hasserjian RP, Arber DA, Reichard K, Hsi ED, Bagg A, Rogers HJ, Geyer J, Darbaniyan F, Do KA, Devins KM, Pozdnyakova O, George TI, Cin PD, Greipp PT, Routbort MJ, Patel K, Garcia-Manero G, Verstovsek S, Medeiros LJ, Wang SA, Bueso-Ramos C. Myelodysplastic/myeloproliferative neoplasms-unclassifiable with isolated isochromosome 17q represents a distinct clinico-biologic subset: a multi-institutional collaborative study from the Bone Marrow Pathology Group. Mod Pathol. 2022 Apr;35(4):470-479..PMID: 34775472.

 

Immune Escape Mechanisms in Intravascular Large B-Cell Lymphoma: A Molecular Cytogenetic and Immunohistochemical Study.
Patel N, Slack GW, Bodo J, Ben-Neriah S, Villa D, Durkin L, Socha D, Steidl C, Hsi ED. Am J Clin Pathol. 2022 Apr 1;157(4):578-585. PMID: 34724028.

Xu-Monette ZY, Wei L, Fang X, Au Q, Nunns H, Nagy M, Tzankov A, Zhu F, Visco C, Bhagat G, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Sun X, Han X, Go H, Ponzoni M, Ferreri AJM, Møller MB, Parsons BM, van Krieken JH, Piris MA, Winter JN, Li Y, Xu B, Albitar M, You H, Young KH. Genetic Subtyping and Phenotypic Characterization of the Immune Microenvironment and MYC/BCL2 Double Expression Reveal Heterogeneity in Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2022 Mar 1;28(5):972-983. doi: 10.1158/1078-0432.CCR-21-2949. PMID: 34980601.

Vega F, Amador C, Chadburn A, Hsi ED, Slack G, Medeiros LJ, Feldman AL. Genetic profiling and biomarkers in peripheral T-cell lymphomas: current role in the diagnostic work-up. Mod Pathol. 2022 Mar;35(3):306-318. doi: 10.1038/s41379-021-00937-0. Epub 2021 Sep 28. PMID: 34584212.

Baker JA, Sireci AN, Marella N, Cannon HK, Marquart TJ, Holzer TR, Reising LO, Cook JD, Wijayawardana SR, Bodo J, Hsi ED, Schade AE, Oakley GJ. Analytical Accuracy of RET Fusion Detection by Break-Apart Fluorescence In Situ Hybridization. Arch Pathol Lab Med. 2022 Mar 1;146(3):351-359. doi: 10.5858/arpa.2020-0376-OA. PMID: 34232984.

Fadeyi EA, Warren CS, Maracaja DLV, Pomper GJ. The use of low volume RBC units for transfusion. Transfusion. 2022 Mar 1. doi: 10.1111/trf.16843. PMID: 35229898.

Amato R, Gardin JF, Tooze JA, Cline JM. Organ Weights in Relation to Age and Sex in Cynomolgus Monkeys (Macaca fascicularis). Toxicol Pathol. 2022 Apr 6:1926233221088283. doi: 10.1177/01926233221088283. Epub ahead of print. PMID: 35383510.

Albitar M, Zhang H, Goy A, Xu-Monette ZY, Bhagat G, Visco C, Tzankov A, Fang X, Zhu F, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Huh J, Ponzoni M, Ferreri AJM, Møller MB, Parsons BM, van Krieken JH, Piris MA, Winter JN, Li Y, Xu B, Young KH. Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms. Blood Cancer J. 2022 Feb 1;12(2):25. doi: 10.1038/s41408-022-00617-5. PMID: 35105854; PMCID: PMC8807629.

Al Abdi S, Almoushref A, Naal T, Melillo CA, Aulak KS, Ahmed MK, Chatterjee S, Highland KB, Dweik RA, Tonelli AR. Cutaneous iontophoresis of vasoactive medications in patients with scleroderma-associated pulmonary arterial hypertension. Microcirculation. 2021 Nov 6:e12734. doi: 10.1111/micc.12734. Epub ahead of print. PMID: 34741773.

Fadeyi EA, Saha AK, Soltani S, Naal T, Palmer R, Bakht A, Warren CS, Simmons JH, Pomper GJ. A com-parison between liquid group A plasma and thawed group A plasma for massive transfusion activation in trauma patients. Vox Sang. 2021 Nov 2. doi: 10.1111/vox.13210. Epub ahead of print. PMID: 34725834.

Sun FJ, Crim MJ, Leblanc M. Edwardsiella ictaluri in a Colony of Zebrafish (Danio rerio) Used in a Teaching Laboratory. Comp Med. 2021 Aug 1;71(4):318-322. doi: 10.30802/AALAS-CM-21-000034. Epub 2021 Jun 29. PMID: 34187617; PMCID: PMC8384001.

Johnson CS, Shively C, Michalson KT, Lea AJ, DeBo RJ, Howard TD, Hawkins GA, Appt SE, Liu Y, McCall CE, Herrington DM, Ip EH, Register TC, Snyder-Mackler N. Contrasting effects of Western vs Mediterranean diets on monocyte inflammatory gene expression and social behavior in a primate model. Elife. 2021 Aug 2;10:e68293. doi: 10.7554/eLife.68293. PMID: 34338633; PMCID: PMC8423447.

Commentary: Bergey CM. Western diet shifts immune cell balance. Elife. 2021 Sep 13;10:e72787. doi: 10.7554/eLife.72787. PMID: 34515026; PMCID: PMC8437433.

Humphries C, Petty DR, Li W. Complex Fibroadenoma with Pronounced Squamous Metaplasia: A Rare Case Report, Differential Diagnostic Considerations, and Associated Breast Cancer Risk. Int J Surg Pathol. 2021 Sep 13:10668969211035842. doi: 10.1177/10668969211035842. Epub ahead of print. PMID: 34516324.

Tang G, Tam W, Short NJ, Bose P, Wu D, Hurwitz SN, Bagg A, Rogers HJ, Hsi ED, Quesada AE, Wang W, Miranda RN, Bueso-Ramos CE, Medeiros LJ, Nardi V, Hasserjian RP, Arber DA, Orazi A, Foucar K, Wang SA. Myeloid/lymphoid neoplasms with FLT3 rearrangement. Mod Pathol. 2021 Sep;34(9):1673-1685.

4. Hamadeh F, Smith MR, Hsi ED. Crystal-storing histiocytes in ascites leading to a diagnosis of plasma cell myeloma. Diagn Cytopathol. 2021 Sep;49(9):E336-E339.

Harrison, W.T., Lusk, J.B., Liu, B. et al. Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old. Acta Neuropathol (2021).

Gurnari C, Pagliuca S, Durkin L, Terkawi L, Awada H, Kongkiatkamon S, Zawit M, Hsi ED, Carraway HE, Rogers HJ, Visconte V, Maciejewski JP Vacuolization of hematopoietic precursors: an enigma with multiple etiologies. Blood. 2021 Jul 1;137(26):3685-3689.

Duns G, Viganò E, Ennishi D, Sarkozy C, Hung SS, Chavez E, Takata K, Rushton C, Jiang A, Ben-Neriah S, Woolcock BW, Slack GW, Hsi ED, Craig JW, Hilton LK, Shah SP, Farinha P, Mottok A, Gascoyne RD, Morin RD, Savage KJ, Scott DW, Steidl C Characterization of DLBCL with a PMBL gene expression signature. Blood. 2021 Jul 15;138(2):136-148.

Patel BJ, Barot SV, Xie Y, Cook JR, Carraway HE, Hsi ED. Impact of next generation sequencing results on clinical management in patients with hematological disorders Leuk Lymphoma. 2021 Jul;62(7):1702-1710.

You H, Xu-Monette ZY, Wei L, Nunns H, Nagy ML, Bhagat G, Fang X, Zhu F, Visco C, Tzankov A, Dybkaer K, Chiu A, Tam W, Zu Y, Hsi ED, Hagemeister FB, Huh J, Ponzoni M, Ferreri AJM, Møller MB, Parsons BM, Van Krieken JH, Piris MA, Winter JN, Li Y, Au Q, Xu B, Albitar M, Young KH. Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma. Oncoimmunology. 2021 Jul 20;10(1):1928365.

Sun FJ, Crim MJ, Leblanc M. Edwardsiella ictaluri in a Colony of Zebrafish (Danio rerio) Used in a Teaching Laboratory. Comp Med. 2021 Aug 1;71(4):318-322. doi: 10.30802/AALAS-CM-21-000034. Epub 2021 Jun 29. PMID: 34187617; PMCID: PMC8384001.

Azad Bakht, MD, Bettina Turner, MT(ASCP)SBB, Christina S Warren, MT(ASCP)SBB, Julie H Simmons, MPH, MT(ASCP)SBB, Emmanuel A Fadeyi, MD, Anti-S Antibody: A Rare Cause of Fetal Hydrops in a Previously Sensitized Mother, Laboratory Medicine, 2021;, lmab014.

Goodrow A, Wachtman L, Benedic W, Allen-Worthington K, Bakker J, Burns M, Diaz LL, Dick E, Dickerson M, Eliades SJ, Gonzalez O, Graf D, Haroush K, Inoue T, Izzi J, Laudano A, Laune-Colon D, Leblanc M, Ludwig B, Mejia A, Miller C, Sarfaty A, Sosa M, Vallender E, Brown C, Forney L Schultz-Darken N, Colman R, Power M, Capuano S, Ross C, Tardif S. Current practices in nutrition management and disease incidence of common marmosets (Callithrix jacchus). J Med Primatol. 2021 Jun; 50(3):164-175.

Bruehl FK, Azzato E, Durkin L, Farkas DH, Hsi ED, Ondrejka SL. Inflammatory Pseudotumor-Like Follicular/Fibroblastic Dendritic Cell Sarcomas of the Spleen Are EBV-Associated and Lack Other Commonly Identifiable Molecular Alterations. Int J Surg Pathol. 2021 Jun;29(4):443-446.

Palavecino E, Kilic A. Characterization of carbapenem-resistant Pseudomonas aeruginosa in a university hospital, United States. Infect Dis (Lond). 2021 May;53(5):396-398. doi: 10.1080/23744235.2020.1867764.

Norouzi M, Norouzi S, Ruggiero A, Khan MS, Myers S, Kavanagh K, Vemuri R. Type-2 Diabetes as a Risk Factor for Severe COVID-19 Infection Microorganisms 2021, 9(6), 1211;

Bradley LM, McDonald, AG, Lantz PE. Fatal systemic (paradoxical) air embolism diagnosed by postmortem funduscopy J. Forensic Sci. 2021;00:1-6.

Willey JS, Britten RA, Blaber E, Tahimic CGT, Chancellor J, Mortreux M, Sanford LD, Kubik AJ, Delp MD, Mao XW. The individual and combined effects of spaceflight radiation and microgravity on biologic systems and functional outcomes.J Environ Sci Health C Toxicol Carcinog. 2021;39(2):129-179. doi: 10.1080/26896583.2021.1885283.PMID: 33902391

Chan J, Yao W, Howard TD, Hawkins GA, Olivier M, Jorgensen MJ, Cheeseman IH, Cole SA, Cox LA. Efficiency of whole-exome sequencing in old world and new world primates using human capture reagents. J Med Primatol. 2021 Apr 19. doi: 10.1111/jmp.12524. Epub ahead of print. PMID: 33876458.

Nguyen KT, Gates CA, Hassell JE, Foxx CL, Salazar SN, Luthens AK, Arnold AL, Elam BL, Elsayed AI, Leblanc M, Adams SE, Lowry CA, Reuter JD. Evaluation of the effects of altitude on biological signatures of inflammation and anxiety- and depressive-like behavioral responses. Progress in Neuropsychopharmacology & Biological Psychiatry. Apr 2021;110331. doi: 10.1016/j.pnpbp.2021.110331. Online ahead of print.

Gu X, Tohme R, Tomlinson B, Sakre N, Hasipek M, Durkin L, Schuerger C, Grabowski D, Zidan AM, Radivoyevitch T, Hong C, Carraway H, Hamilton B, Sobecks R, Patel B, Jha BK, Hsi ED, Maciejewski J, Saunthararajah Y. Decitabine- and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network. Leukemia. 2021 Apr;35(4):1023-1036

Goyal T, Ondrejka SL, Bodo J, Durkin L, Hsi ED. Lack of activation-induced cytidine deaminase expression in in situ follicular neoplasia. Haematologica. 2021 Apr 1;106(4):1212-1215

Childs DD, Rocha Lima CMSP, Zhou Y. Mucin-Containing Rectal Cancer: A Review of Unique Imaging, Pathology, and Therapeutic Response Features. Semin Roentgenol. 2021 Apr;56(2):186-200. doi: 10.1053/j.ro.2020.07.010. Epub 2020 Jul 30. PMID: 33858645.

Li W, Justice-Clark T, Cohen MB. The utility of ThyroSeq in the management of indeterminate thyroid nodules by fine-needle aspiration. Cytopathology. 021;00:1– 8.

Yu D, Giffen MA Jr., Suicidal iron overdose: A case report and review of literature, J Forensic Sci. 2021 Mar 17. doi: 10.1111/1556-4029.14701. Online ahead of print. PMID: 33729557

Huang Richard S. P., Severson Eric, Haberberger James, Duncan Daniel L., Hemmerich Amanda, Edgerly Claire, Ferguson N. Lynn, Frampton Garrett, Owens Clarence, Williams Erik, Elvin Julia, Vergilio Jo-Anne, Killian Jonathan Keith, Lin Douglas, Morley Samantha, McEwan Deborah, Holmes Oliver, Danziger Natalie, Cohen Michael B., Sathyan Pratheesh, McGregor Kimberly, Reddy Prasanth, Venstrom Jeffrey, Anhorn Rachel, Alexander Brian, Brown Charlotte, Ross Jeffrey S., Ramkissoon Shakti H., Landscape of Biomarkers in Non-small Cell Lung Cancer Using Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry, Pathology and Oncology Research, Volume 27:6, 2021. DOI=10.3389/pore.2021.592997. ISSN=1532-2807.

Invited Editorial Comment and Podcast recording as editorialist: Melendez Giselle C., MR-derived Regional Strain and Radiation-induced Cardiotoxicity: The Importance of Myocardial Inflammation, J Am Coll Cardiol CardioOnc. 2021 Mar, 3 (1) 131–133.

Kavanagh K, Sherrill C, Ruggiero A, Block M, Vemuri R, Davis MA, Olivier A. Biomarkers of Senescence in Non-Human Primate Adipose Depots Relate to Aging. GeroScience 42(6):1649-1661 PMID: 32588342 PMCID: PMC7732933

Ruggiero AD, Davis A, Sherrill C, Westwood B, Chou J, Reeves T, Cox LA, Kavanagh K. Changes in Skeletal Muscle Remodeling and Capillary Density in Metabolic Disease. American Journal of Physiology PMID: 33206559 doi: 10.1152/ajpregu.00240.2020. PMID: 33206559 2020

Ruggiero AD, Key CC, Kavanagh K. Adipose Tissue Macrophage Polarization in Healthy and Unhealthy Obesity. Frontiers in Nutrition 2021 in press doi: 10.3389/fnut.2021.625331

Harrison DE, Strong R, Reifsnyder P, Kumar S, Fernandez E, Flurkey K, Javors MA, Macchiarini F, Nelson JF, Bitto A, Markewych A, Sindlerb AL, Gano LB, Brenner CM, Holloszy JO, Cortopassi G, Kavanagh K, Bucala R, Rosenthal N, Lombard D, Salmon A, Bogue M, Ladiges W, Snyder J, Miller RA. 17-alpha-estradiol late in life extends lifespan in aging HET3 male mice; four other drugs did not affect lifespan in either sex. Aging Cell 2021 in press DOI: 10.1111/acel.13328

Rabina Mainali, Manal Zabalawi, David Long, Nancy Buechler, Ellen Quillen, Chia-Chi Key, Xuewei Zhu, John S. Parks, Cristina Furdui, Peter W. Stacpoole, Jennifer Martinez, Charles E. McCall, Matthew Quinn; Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

Pharmacological profile and ocular hypotensive effects of cromakalim prodrug 1 (CKLP1), a novel ATP-sensitive potassium channel opener, in normotensive dogs and nonhuman primates. Uttio Roy Chowdhury_¹, Rachel A. Kudgus², Bradley H. Holman¹, Tommy A. Rinkoski¹, Cheryl R. Hann¹, Cindy K. Bahler¹, Eric McCloud³, Susan E Appt³, Joel M. Reid², Peter I. Dosa⁴, Michael P. Fautsch¹. In Press Journal of Ocular Pharmacology and Therapeutics.
1 Department of Ophthalmology, Mayo Clinic, Rochester, MN, United States of America, 2 Department of Oncology Research, Mayo Clinic, Rochester, MN, United States of America, 3Department of Pathology, Section of Comparative Medicine, Wake Forest School of Medicine, 4 Department of Medicinal Chemistry, Institute for Therapeutics Discovery and Development, University of Minnesota, Minneapolis, MN, United States of America

Sakshi Gera (Matthew Quinn) et.al. First-in-class humanized FSH blocking antibody targets bone and fat. Proc Natl Acad Sci U S A 2020 Nov 17;117(46):28971-28979. doi: 10.1073/pnas.2014588117. Epub 2020 Oct 30.

Dewi FN, Cline JM. Nonhuman primate model in mammary gland biology and neoplasia research. Lab Anim Res. 2021 Jan 5;37(1):3. doi: 10.1186/s42826-020-00053-1. PMID: 33397518; PMCID: PMC7784333.

Goel E, Erwin M, Cawthon CV, Schaff C, Fedor N, Rayl T, Wilson O, Christians U, Register TC, Geary RL, Saul J, Yazdani SK. Pre-Clinical Investigation of Keratose as an Excipient of Drug Coated Balloons. Molecules. 2020. doi: 10.3390/molecules25071596. PubMed PMID: 32244375; PubMed Central PMCID: PMC7180741.

Frye BM, Craft S, Register TC, Andrews RN, Appt SE, Vitolins MZ, Uberseder B, Silverstein-Metzler MG, Chen H, Whitlow CT, Kim J, Barcus RA, Lockhart SN, Hoscheidt S, Say BM, Corbitt SE, Shively CA. Diet, psychosocial stress, and Alzheimer’s disease-related neuroanatomy in female nonhuman primates. Alzheimers Dement. 2020 Dec 3. doi: 10.1002/alz.12232. Epub ahead of print. PMID: 33270373.

Shively CA, Appt SE, Chen H, Day SM, Frye BM, Shaltout HA, Silverstein-Metzler MG, Snyder-Mackler N, Uberseder B, Vitolins MZ, Register TC. Mediterranean diet, stress resilience, and aging in nonhuman primates. Neurobiol Stress. 2020 Oct 19;13:100254. doi: 10.1016/j.ynstr.2020.100254. PMID: 33344709; PMCID: PMC7739065.

Frye BM, Craft S., Latimer CS, Keene CD, Montine TJ, Register TC, Orr ME, Kavanagh K, Macauley SL, Shively CA. Aging related Alzheimer’s disease-like neuropathology and functional decline in captive vervet monkeys (Chlorocebus aethiops sabaeus). American Journal of Primatology, in press.

Petropoulou PI, Mosialou I, Shikhel S, Hao L, Panitsas K, Bisikirska B, Luo N, Bahna F, Kim J, Carberry P, Zanderigo F, Simpson N, Bakalian M, Kassir S, Shapiro L, Underwood MD, May CM, Soligapuram Sai KK, Jorgensen MJ, Confavreux CB, Shapses S, Laferrère B, Mintz A, Mann JJ, Rubin M, Kousteni S. Lipocalin-2 is an anorexigenic signal in primates. Elife. 2020 Nov 24;9:e58949. doi: 10.7554/eLife.58949. PMID: 33231171; PMCID: PMC7685704.

Plant M, Armstrong C, Ruggiero A, Sherrill C, Uberseder B, Jeffries R, Nevarez J, Jorgensen MJ, Kavanagh K, Quinn MA. Advanced maternal age impacts physiologic adaptations to pregnancy in vervet monkeys. Geroscience. 2020 Dec;42(6):1649-1661. doi: 10.1007/s11357-020-00219-8. Epub 2020 Jun 25. PMID: 32588342; PMCID: PMC7732933.

Kavanagh K, Sherrill C, Ruggiero A, Block M, Vemuri R, Davis MA, Olivier A. Biomarkers of Senescence in Non-Human Primate Adipose Depots Relate to Aging. GeroScience 42(6):1649-1661 PMID: 32588342 PMCID: PMC7732933

Ruggiero AD, Davis A, Sherrill C, Westwood B, Chou J, Reeves T, Cox LA, Kavanagh K. Changes in Skeletal Muscle Remodeling and Capillary Density in Metabolic Disease. American Journal of Physiology PMID: 33206559 doi: 10.1152/ajpregu.00240.2020. PMID: 33206559 2020Ruggiero AD, Key CC, Kavanagh K. Adipose Tissue Macrophage Polarization in Healthy and Unhealthy Obesity. Frontiers in Nutrition 2021 in press doi: 10.3389/fnut.2021.625331

Wajih N, Alipour E, Rigal, F, Zhu, J, Perlegas A, Caudell DL, and Kim-Shapiro D. Effects of Nitrite and Far-red Light on Coagulation, Nitric Oxide, 2021 Feb 107: 11-18. PMID: 33271226

Gmeiner WH, Dominijanni A, Ghirardelli, L, Caudell, DL, D’Agostino Jr. R, Pasche B, Smith TL, Deng Z, Kiren S, Mani C, Palle K, Haber A, Brody JR. The Fluoropyrimidine Polymer CF10 Displays Improved anti-Tumor Activity in pre-Clinical Colorectal Cancer Models thru Distinct Mechanistic and Pharmacological Properties. Mol Cancer Ther, In Press

Mao XW, Nishiyama NC, Byrum SD, Stanbouly S, Jones T, Holley J, Sridharan V, Boerma M, Tackett AJ, Willey JS, Pecaut MJ, Delp MD. Spaceflight induces oxidative damage to blood-brain barrier integrity in a mouse model. FASEB J. Sep 26. doi: 10.1096/fj.202001754R. PMID: 32981077

Jinnah AH, Whitlock P, Willey JS, Danelson K, Kerr AK, Hassan OA, Emory C, Smith TL, Bracey DN. Improved osseointegration using porcine xenograft compared to demineralized bone matrix for the treatment of critical defects in a small animal model. Xenotransplantation. 2020 Nov 26;e12662.; https://doi.org/10.1111/xen.12662 PMID: 33242920

* da Silveira WA, Fazelinia H, Rosenthal SB, Laiakis EC, Kim MS, Meydan C, Kidane Y, Rathi KS, Smith SM, Stear B, Ying Y, Zhang Y, Foox J, Zanello S, Crucian B, Wang D, Nugent A, Costa HA, Zwart SR, Schrepfer S, Elworth RAL, Sapoval N, Treangen T, MacKay M, Gokhale NS, Horner SM, Singh LN, Wallace DC, Willey JS*, Schisler JC*, Meller RM*, McDonald JT*, Fisch KM*, Hardiman G*, Taylor D*, Mason CE*, Costes SV*, Beheshti A*. Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact. Cell. 2020 Nov 25;183(5):1185-1201.e20. doi: 10.1016/j.cell.2020.11.002. PMID: 33242417 Denotes CO-SENIOR Authorship: Media Coverage for our Paper in Cell.

Maracaja DLV, Qiao J, Salazar T, Barry J, LaForce K, Holder K, Olson JD. A Flow Cytometric Study of Reagent Cells to Resolve ABO Typing Discrepancy. Am J Clin Pathol. 2021 Jan 4;155(1):117-123. PMID: 33049048

Maracaja DLV, Puthenpura V, Pels SG, O'Malley DP, Sklar JL, Finberg KE, Xu ML. EBV-Positive Primary Large B-Cell Lymphoma: The Role of Immunohistochemistry and XPO1 in the Diagnosis of Mediastinal Lymphomas. Appl Immunohistochem Mol Morphol. 2020 Nov/Dec;28(10):725-730. PMID: 31789821.

Schuetz AN, Hemarajata P, Mehta N, Campbell S, Mitchell S, Palavecino E, Butler-Wu S, Miller MB.When Should Asymptomatic Persons Be Tested for COVID-19? J Clin Microbiol. 2020 Dec 17;59(1):e02563-20. doi: 10.1128/JCM.02563-20. Print 2020 Dec 17. PMID: 33023910

Socha DS, Zhao X, Bodo J, Durkin L, Hsi ED. Decreased BIM expression in BCL2-negative follicular lymphoma: a potential mechanism for resistance to apoptosis. Hum Pathol. 2021 Jan;107:1-8. PMID: 33039369

Vega F, Amador C, Chadburn A, Feldman AL, Hsi ED, Wang W, Medeiros LJ. American Registry of Pathology Expert Opinions: Recommendations for the diagnostic workup of mature T cell neoplasms. Ann Diagn Pathol. 2020 Dec;49:151623; PMID: 32947231