The Tumor Tissue and Pathology Shared Resource (TTPSR) at Wake Forest Baptist Comprehensive Cancer Center (WFBCCC) consists of three well-integrated laboratories, all equipped with state-of-the-art instrumentation and overseen by certified pathologists and trained staff:


The mission of the TTPSR is to facilitate translational cancer research by:

  • Collecting and supplying high-quality, well-characterized human and animal tissues (neoplastic and normal)
  • Providing various pathology services to WFBCCC investigators

The TTPSR carries out this mission by:

  • Maintaining a repository of patient-derived tumors and matched normal tissues in addition to tissues from other species that are accompanied by pertinent clinical information
  • Facilitating investigators’ access to available tumor and normal tissues, serum, plasma, and white blood cell data via the institutional Data Warehouse and i2b2, as well as the Shared Resource’s web-based biospecimen management tool, in a regulatory-compliant manner.
  • Providing scientific and pathology expertise to support the development of clinical protocols, grant applications, and manuscripts

The TTPSR also assists investigators with the customized collection of fresh human and animal tissue samples for prospective translational research projects.

Examples of Science Supported

  • Brain metastasis working group
  • Appendiceal cancer research group
  • Ovarian cancer
  • Papillary thyroid cancer
  • Prostate cancer
  • Breast cancer
  • Radiation research
  • Colon cancer
  • HIV research
  • Vaccine development