The CRBM has an annual open call for proposals to support pilot projects in the area of redox biology and medicine. The Request for Applications is issued once a year, with the Letter of Intent due mid-September and full applications due mid-October. Specific criteria include:
- Building new collaborations between members and with researchers from other centers
- Fostering clinical connections with research in the area of redox biology and medicine
- Providing a high potential to inspire new multi-investigator extramural grants (P01s, R01s, U01s, etc)
2024 Request for Pilot Grant Applications
Previously Funded Projects
2020 Project Highlights
W. Todd Lowther, PhD (Biochemistry), Inhibition of Peroxiredoxin 3 with Novel Compounds for Cancer Redox Therapy (co-funded with CCC)
Kiran Kumar Solingapuram Sai, PhD (Radiology), Evaluation of [18F]KS1, A Novel Ascorbate-Based PET Imaging Agent in Non-Human Primate Tumor Model of Radiation (co-funded with CCC)
John Lukesh, PhD (Chemistry) and Leslie B. Poole, PhD (Biochemistry), The Development of New Chemical Tools to Further Probe the Beneficial Effects of Reactive Sulfur Species on Cardiovascular Health and Protection (co-funded with WFU Center for Molecular Signaling).
- David Caudell, DVM/PhD (Pathology – Comparative Med), Radiation-Induced Oxidative Injury During Megakaryocyte Differentiation
- Thomas Hollis, PhD (Biochemistry), Redox Regulation of Deoxynucleotide Metabolism and Cell Cycle Regulation
- David Soto-Pantoja, PhD (Hypertension), TSP1/CD47 blockade prevents chemotherapy related cardiotoxicity
- Xuewei Zhu, PhD (Mol Medicine), Pyruvate Oxidation Regulates Canonical and Non-canonical NLRP3 Inflammasome by Targeting Redox Pathways
- Gagan Deep, PhD (Cancer Biology), Exosomes secretion promote survival of African American prostate cancer cells under hypoxia through alleviating intracellular oxidative stress
- Reto Asmis, PhD (Mol Medicine), Redox Regulation of Pyruvate Kinase M2 and Macrophage Polarization
- Hariom Yadav, PhD (Mol Medicine) and Dany Kim-Shapiro, PhD (WFU Physics), Development of Nitrate-Reducing and Nitric Oxide Producing Probiotics
- Yuanyuan Zhang, MD/PhD (WFIRM) , Patient-derived Urinary Stem Cells as a Novel Biomarker for Diabetic Nephropathy
- Pierre-Alexandre Vidi, PhD (Cancer Biol) and Keith Bonin, PhD (WFU Physics), Mechanosignaling in the maintenance of genomic integrity
- Allen Tsang, PhD (Mol Medicine and Heather Brown-Harding, PhD (WFU Biology), Exploring the Therapeutic Potential of Spilanthol in Chlamydia Infection
- Liliya M. Yamaleyeva, MD (Surgery/Hypertension and Vascular Research), Redox Imbalance as a Modifier of Cardiometabolic Risk in African Americans Women: The Multi-Ethnic Study of Atherosclerosis
- Thomas Hollis, PhD (Biochem) and Neveen Said, MD/PhD (Cancer Biol), Nucleotide Metabolism and Regulation of Cell Cycle Progression
- Leslie Poole, PhD (Biochem) and JasminaVaragic, MD/PhD (Surgery/Hypertension and VascularResearch), Mechanisms of Protection Against Doxorubicin Cardiotoxicity by Dietary Nitrates
- Katherine Schafer, MD (Infectious Disease) and Allen Tsang, PhD (Mol Medicine), A Translational Approach to Dissect the Impact of Reactive Oxygen Species in HIV/Aging Associated Cancers
- Raghunatha Yammani, PhD (Mol Medicine), Redox Regulation of Unfolded Protein Response (UPR) Signaling Pathway and Its Role in Osteoarthritis
- Vidula Vachharajani, MD (Anesthesiology) and Dany Kim-Shapiro, PhD (WFU Physics), Red Blood CellMediated Nitrite Signaling in Diabetes
- Rebecca Alexander, PhD (WFU Chemistry), Intramolecular and Intracellular Signaling by a tRNA Base Modifying Enzyme