The Department of Internal Medicine announced awards for the top research papers published in 2020 during Grand Rounds on May 6. The 15 papers were selected on the basis of their originality and their scientific and clinical impact and span the spectrum of basic, clinical, and healthcare delivery science. This year’s awards brought together department members from both Wake Forest Baptist Health and Atrium Health, and provide a clear example that the two departments are “better together.”
The papers represent the creativity, passion and dedication of our faculty and trainees. The papers further demonstrate the department’s commitment to improve the health of the patients we serve by advancing understanding of the mechanisms of disease, by testing novel therapies, and by building and implementing the evidence base for clinical practice. Lastly, the papers represent the Department’s long-term goal of advancing a preeminent Academic Learning Health System.
Please join leaders Gary E. Rosenthal, MD, FACP, David M. Herrington, MD, PhD, MHS, and Scott L. Furney, MD, in congratulating this year’s awardees. These 15 papers represent just the tip of the iceberg of the wonderful research done by so many faculty and trainees in the department.
- Age-Related Decline in Expression of Molecular Chaperones Induces Endoplasmic Reticulum Stress and Chondrocyte Apoptosis in Articular Cartilage
Authors: Li Tan, PhD (WFSM), Raghunatha R. Yammani, PhD (WFSM) - Brain-Specific Repression of AMPKα1 Alleviates Pathophysiology in Alzheimer’s Model Mice
Authors: Helena R. Zimmermann, PhD (WFSM), Tao Ma, PhD (WFSM) - Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans
Author: Swapan K. Das, MSc, PhD (WFSM) - Tumour Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) and Receptors in Type 1, Type 2 and Type 17 Inflammation in Cross-Sectional Asthma Study
Authors: Michelle M. Marks, MD (WFSM), Annette T. Hastie, PhD (WFSM) - Clinical and Genetic Spectra of Autosomal Dominant Tubulointerstitial Kidney Disease Due to Mutations in UMOD and MUC1
Author: Anthony J. Bleyer, Sr., MD, MS (WFSM) - Safety, Efficacy, and Feasibility of Intranasal Insulin for the Treatment of Mild Cognitive Impairment and Alzheimer Disease Dementia: A Randomized Clinical Trial
Author: Suzanne Craft, PhD (WFSM) - Carfilzomib, Dexamethasone, and Daratumumab versus Carfilzomib and Dexamethasone for Patients with Relapsed or Refractory Multiple Myeloma (CANDOR): Results from a Randomised, Multicentre, Open-Label, Phase 3 Study
Author: Saad Z. Usmani, MD, MBA, FACP (Atrium Health) - Association of Reduced-Intensity Conditioning Regimens with Overall Survival Among Patients with Non-Hodgkin Lymphoma Undergoing Allogeneic Transplant
Author: Nilanjan Ghosh, MD, PhD (Atrium Health) - Association between Systolic Ejection Time and Outcomes in Heart Failure by Ejection Fraction
Author: Priyesh A. Patel, MD (Atrium Health) - Effect of Intensive Glycemic and Blood Pressure Control on QT Prolongation in Diabetes: The ACCORD Trial
Authors: Matthew J. Singleton, MD, MBE, MHS, MSc (WFSM), Joseph Yeboah, MD, MS (WFSM) - Screening of Potential Cardiac Involvement in Competitive Athletes Recovering from COVID-19: An Expert Consensus Statement
Author: Dermot M. Phelan, MD, PhD, FASE, FACC (Atrium Health) - New ACC Global Heart Attack Treatment Initiative: Improving STEMI Care Worldwide
Author: B. Hadley Wilson, MD, FACC (Atrium Health) - Effects of Intensive Systolic Blood Pressure Control on All-Cause Hospitalizations
Author: Michael V. Rocco, MD, MSCE (WFSM) - Security and Privacy Risks Associated With Adult Patient Portal Accounts in US Hospitals
Author: David P. Miller, Jr., MD, MS, FACP (WFSM) - Insights from Rapid Deployment of a “Virtual Hospital” as Standard Care During the COVID-19 Pandemic
Authors: Kranthi Sitammagari, MD, FACP, CHCQM-PHYADV (Atrium Health), Andrew McWilliams, MD, MPH (Atrium Health)