Wei Zhang, PhD

About Me

Research Laboratory

Wei Zhang Lab - Providing research in cancer genomics and precision oncology.

Education Program Involvement

Cancer Biology PhD
Program Research Interest: Cellular defense and metabolism, Aberrant signaling pathways in tumor cells, Cell growth and survival, Molecular cancer epidemiology, Gene-environment interactions, Cancer control

Biomedical Engineering PhD
Program Research Interest: Biomaterials, Biomechanics, Biomedical Imaging, Cardiovascular Engineering, Nanomedicine and Nanobioengineering, Neuroengineering, Tissue Engineering, Translational Cancer Research

Research

Publications

Association of MUC16 Mutation With Tumor Mutation Load and Outcomes in Patients With Gastric Cancer. Li X, Pasche B, Zhang W, Chen K. JAMA Oncol. 2018 12; 4(12):1691-1698.
miR-30 disrupts senescence and promotes cancer by targeting both p16INK4A and DNA damage pathways. Su W, Hong L, Xu X, Huang S, Herpai D, Li L, Xu Y, Truong L, Hu WY, Wu X, Xiao C, Zhang W, Han J, Debinski W, Xiang R, Sun P. Oncogene. 2018 10; 37(42):5618-5632.
Nuclear ß-catenin localization and mutation of the CTNNB1 gene: a context-dependent association. Kim G, Kurnit KC, Djordjevic B, Singh C, Munsell MF, Wang WL, Lazar AJ, Zhang W, Broaddus R. Mod. Pathol. 2018 10; 31(10):1553-1559.
Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1. Liu L, Ruiz J, O'Neill SS, Grant SC, Petty WJ, Yang M, Chen K, Topaloglu U, Pasche B, Zhang W. Mol. Cancer. 2018 04; 17(1):81.
Pathogenic Germline Variants in 10,389 Adult Cancers. Huang KL, Mashl RJ, Wu Y, Ritter DI, Wang J, Oh C, Paczkowska M, Reynolds S, Wyczalkowski MA, Oak N, Scott AD, Krassowski M, Cherniack AD, Houlahan KE, Jayasinghe R, Wang LB, Zhou DC, Liu D, Cao S, Kim YW, Koire A, McMichael JF, Hucthagowder V, Kim TB, Hahn A, Wang C, McLellan MD, Al-Mulla F, Johnson KJ, Lichtarge O, Boutros PC, Raphael B, Lazar AJ, Zhang W, Wendl MC, Govindan R, Jain S, Wheeler D, Kulkarni S, Dipersio JF, Reimand J, Meric-Bernstam F, Chen K, Shmulevich I, Plon SE, Chen F, Ding L. Cell. 2018 04; 173(2):355-370.e14.

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Research Focus Areas

Translation to Care

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Wei Zhang, PhD

About Me

Research Laboratory

Education Program Involvement