The research interests of the faculty are focused in four inter-related areas that address fundamentally important biological questions:
- Signal transduction in cancer and inflammation
- Nucleic acid metabolism in cancer and inflammation
- Redox biology
- Metabolic diseases such as diabetes and atherosclerosis
The Department features research and training in four key technologies that form the core of modern Biochemistry:
- Structural Biology
- Molecular Biology
Research in the Department of Biochemistry is highly collaborative. Faculty members and students participate in the activities of a variety of research centers whose missions include promoting research collaborations. These include:
- T32-GM095440 “Structural and Computational Biophysics Training Program”
- T32-HL091797 “Integrative Lipid Metabolism, Inflammation, and Chronic Diseases”
- T32-AI007401 “Training Program in Immunology and Pathogenesis”
- T32- CA079448 “Training Program in Cancer Biology”
Laboratories for macromolecular X-ray crystallography as well as rapid reaction kinetics, time-resolved fluorescence spectroscopy, circular dichroism spectroscopy, phosphorimaging, dynamic light scattering, cellular imaging, and analytical ultracentrifugation have been established to meet the needs of investigators.
The professionally staffed Biomolecular Resource Core Facilities are also available for protein and DNA sequence analysis, peptide and oligonucleotide synthesis, GC- and tandem mass spectrometry.