Human glioblastoma cells transfected with a lentivirus containing red fluorescent protein and luciferase preparing for intracranial animal implantation.
Neuro-Oncology Research
Brain Tumor Cell Biology Lab: Hsu Lab
- The role of brachyury in chordoma and gliomas
Brain Tumor Research: Debinski Lab (Department of Cancer Biology)
- NIH P30 Grant for the Neuro-Oncology Program – Brain Tumor Center of Excellence
- NIH Program Project Grant P01 (with VA Tech School of Biomedical Engineering)
- “Maximizing Local Access to Therapeutic Deliveries in Glioblastoma”
- R01 High-Grade Astrocytoma-Specific Molecular Targeting
- Understanding the role of checkpoint inhibitors in GBM
Brain Metastases Research Group: Drs. Mike Chan, Ko Watabe, Chris Whitlow, Hui-Wen Lo
- Brain met velocity to inform patient care paradigms: Dr. Mike Chan
- Biomarkers predictive of metastatic histology and radiographic correlates
- tGLI1 in brain metastases
- NIH R01 Role of inflammation and microRNA network in brain metastasis of breast cancer
- NIH R01 Roles of long-non-coding RNA, XIST, in brain metastases of breast cancer
Functional Neurosurgery Research
Development of a human memory prosthesis: Hampson Lab
- DARPA (Defense Advanced Research Projects Agency) Grant
Neurochemical Encoding: Kishida Lab
- NIH R01 Real- time neurochemical encoding of reward
- NIH R01 Neuro-computational approach to determine a neurochemical basis of mood and depression
- NIH R01 Dopaminergic encoding of counterfactual information in the human striatum
Laser Interstitial Thermal Therapy for Mesial Temporal Love Epilepsy: Drs. Couture and Laxton
Spine Neurosurgery Research
Technology development and innovation: Dr. Branch in collaboration with Wake Innovations
- Spinal implants, retractors, imaging technology, outcomes research with QOD
Spine Biomechanics Lab: Drs. Branch, JL Wilson, Brown
- Cadaver studies using kuka robotic repetitive motion to investigate adjacent level disease and fusion construct integrity
Modeling and Treatment for Acute Spinal Cord Injury: Atala Lab
- NIH T32 Studies in Translational Regenerative Medicine
- Duraplasty with Stem Cell Injection in rabbit model of paralysis
- NIH P41 Bioprinting Patterning for Cell-Laden Constructs
Vascular Neurosurgery Research
Cerebrovascular Disease Modeling: Wolfe Lab
- KRAS mutations in sporadic AVMs
- NREF Medical Student Summer Research Grant
- Genomic mutations in human cerebral aneurysms
- CTSI grant: Immune phenotypes following ICH in a hypertensive mREN model
- NREF Medical Student Summer Research Grant 2019
- NREF Medical Student Summer Research Grant 2020
Stroke model of brain organoids under hypoxic/ischemic conditions: Atala lab
Pediatric Neurosurgery Research
TBI/Concussion in Football using accelerometer outfitted helmets with Bioengineering/Radiology
- NIH R01 Neurophysiology of Working Memory Maturation in Adolescence
Park-Reeves Syringomyelia Research Consortium: Dr. Couture
Trauma Research
Rabbit model of spinal cord injury and recovery using autologous stem cell grafting: Marrotte lab
TBI/Concussion in Football using accelerometer outfitted helmets with Bioengineering/Radiology
- NIH P30 iTAKL: Imaging Telemetry and Kinematic modeling in youth football-High School
Clinical Outcomes Neurosurgery Research
- N2QOD
- JA Wilson: Carotid disease, cerebrovascular, patient centered outcomes
- Fargen: IIH, stroke outcomes, endovascular techniques, physician/resident/staff burnout
- JL Wilson: Minimally invasive spine techniques, spine quality outcomes
- Couture: epilepsy outcomes after LITT
- Laxton: Radiosurgery, Neuro-oncology and epilepsy outcomes after LITT
- Tatter: Radiosurgery, Neuro-oncology
- Wolfe: StrokeNET, ICH medical and minimally invasive intervention trials, stroke intervention, endovascular techniques