The Dr. Xuewei Zhu laboratory applies molecular biology and immunology approaches to investigate the molecular link between cellular metabolism and innate immunity.

We study the effect of lipid metabolism, glucose metabolism, and inflammation on the pathogenesis of chronic metabolic diseases such as atherosclerosis, diabetes and obesity; as well as their effect on acute inflammatory diseases such as sepsis. 

To accomplish the goals of our grant projects, we use an interdisciplinary approach that includes:

  • Molecular biology
  • Immunology
  • Cell biology
  • Bioenergetics
  • Omics technology (transcriptomics, metabolomics and others) 
  • Transgenic mouse models of human diseases
  • Cell lines and primary cells from mice

We invite you to explore our lab’s research.