The Metabolic Phenotyping Shared Resource (MPSR) provides advanced indirect calorimetry services, technologies and scientific consultation.
We collaborate with researchers to characterize metabolic phenotypes of rodent models with obesity, aging, diabetes, cardiovascular disease, Alzheimer's disease, and cancer.
Key CC, Bishop AC, Wang X, Zhao Q, Chen GY, Quinn MA, Zhu X, Zhang Q, Parks JS. Human GDPD3 overexpression promotes liver steatosis by increasing lysophosphatidic acid production and fatty acid uptake. J Lipid Res. 2020 Jul;61(7):1075-1086. doi: 10.1194/jlr.RA120000760. Epub 2020 May 19. PMID: 32430316; PMCID: PMC7328041.
Wang S, Ahmadi S, Nagpal R, Jain S, Mishra SP, Kavanagh K, Zhu X, Wang Z, McClain DA, Kritchevsky SB, Kitzman DW, Yadav H. Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice. Geroscience. 2020 Feb;42(1):333-352. doi: 10.1007/s11357-019-00137-4. Epub 2019 Dec 8. PMID: 31814084; PMCID: PMC7031475.