I have devoted my research career to understanding how environmental factors (particularly social stressors) influence female health, mostly through studies of nonhuman primates (NHPs), with a focus on chronic diseases of aging. This has involved the development of multiple NHP models of human health. We are currently investigating whether consumption of a Mediterranean diet attenuates physiological stress responses, and the deleterious effects of social stress on health that are observed in human and nonhuman primates consuming a Western diet. In recent years my lab, developed a female NHP model of aging and physical function. Using this model, we are investigating the impact of Mediterranean versus Western diets on physical function and metabolic perturbations consistent with a pre-diabetic condition that increases risk for chronic disease of aging. Currently we are assessing the effects of diet and stress on neuropathological characteristics associated with Alzheimer’s disease. My research program is inherently collaborative, multidisciplinary, and translational, as is evident from cross-appointments in Translational Medicine, and Physiology and Pharmacology, and membership in several interdisciplinary intramural research centers.
Carol A Shively Lab - Women's Health, Primate Behavioral Biology, Social Stress and Depression: Opportunities for research are in the general area of the role of social stress in disease susceptibility in nonhuman primates.
Education Program InvolvementIntegrative Physiology and Pharmacology PhD Program Research Interest: Drug and Alcohol Abuse, Cardiovascular Physiology and Hypertension, Regenerative Medicine, Neuro- and Behavioral Pharmacology, Cancer Therapeutics Endocrinology, Diabetes, and Metabolism Lifespan Physiology.
Graduate Programs in Neuroscience
Program Research Interest: Addiction and Substance Abuse, Behavioral and Systems Neurobiology, Development and Plasticity, Molecular Neurobiology, Neurological Disease and Aging, Neuropharmacology, Sensory Neurobiology
Program Research Interest: Analytical approaches to molecular and cellular synthesis, structure and function, Genetics and gene regulation, Cell communications, Organ systems, Pathophysiology