About Me
My research explores how biomarkers influence cardiovascular outcomes, focusing on their pathways and mechanisms in disease progression and risk stratification. Currently, I am investigating the complex interplay between ketone bodies and cardiovascular outcomes to better understand their role in disease modulation. This work seeks to identify potential diagnostic and therapeutic applications to improve cardiovascular care and prevention.
1. Chevli PA, Schaich CL, Wood AC, Tk LA, Mehta A, Jain V, Connelly M, Craft S, Shemesh E, Luchsinger JA, Hayden KM, Sachs BC, Hughes TM, Shapiro MD. Association of circulating ketone bodies with cognitive performance and dementia in the Multi-Ethnic Study of Atherosclerosis (MESA). Alzheimers Dement (Amst). Oct-Dec 2024;16(4):e70039. doi:10.1002/dad2.70039. https://pubmed.ncbi.nlm.nih.gov/39583649/
2. Kazibwe R, Muhammad AI, Singleton MJ, Evans JK, Chevli PA, Namutebi JH, Kazibwe J, Epiu I, German C, Soliman EZ, Shapiro MD, Yeboah J. Self-rated health and risk of incident cardiovascular events among individuals with hypertension. J Hypertens. Sep 1 2024;42(9):1573-1580. doi:10.1097/HJH.0000000000003762. https://pubmed.ncbi.nlm.nih.gov/39088765/
3. Mirzai S, Persits I, Kazibwe R, Gabani M, Seals A, Singleton MJ, Rikhi R, Chevli PA, Carbone S, Tang WHW, Yeboah J, Williamson JD, Kitzman DW, Herrington DM, Shapiro MD. Relationship Between Sarcopenia and Intensive Blood Pressure Control Efficacy and Safety: A Secondary Analysis of SPRINT. Hypertension. Aug 2024;81(8):e77-e87. doi:10.1161/HYPERTENSIONAHA.124.23011. https://pubmed.ncbi.nlm.nih.gov/38881460/
4. Kazibwe R, Schaich CL, Muhammad AI, Epiu I, Namutebi JH, Chevli PA, Kazibwe J, Hughes T, Rikhi RR, Shapiro MD, Yeboah J. Effect of vigorous-intensity physical activity on incident cognitive impairment in high-risk hypertension. Alzheimers Dement. Jul 2024;20(7):4602-4612. doi:10.1002/alz.13887. https://pubmed.ncbi.nlm.nih.gov/38842100/
5. Rikhi R, Schaich CL, Hafzalla GW, Patel NA, Tannenbaum JE, German CA, Polonsky T, Tsai MY, Ahmad MI, Islam T, Chevli PA, Shapiro MD. Small dense low-density lipoprotein cholesterol and coronary artery calcification in the Multi-Ethnic Study of Atherosclerosis. Eur J Prev Cardiol. Jun 3 2024;31(8):1048-1054. doi:10.1093/eurjpc/zwae049. https://pubmed.ncbi.nlm.nih.gov/38323698/
6. Scott DA, Ponir C, Shapiro MD, Chevli PA. Associations between insulin resistance indices and subclinical atherosclerosis: A contemporary review. Am J Prev Cardiol. Jun 2024;18:100676. doi:10.1016/j.ajpc.2024.100676
7. Shemesh E, Chevli PA, Islam T, German CA, Otvos J, Yeboah J, Rodriguez F, deFilippi C, Lima JAC, Blaha M, Pandey A, Vaduganathan M, Shapiro MD. Circulating ketone bodies and cardiovascular outcomes: the MESA study. Eur Heart J. May 7 2023;44(18):1636-1646. doi:10.1093/eurheartj/ehad087
8. Rikhi R, Bhatia HS, Schaich CL, Ashburn N, Tsai MY, Michos ED, Chevli PA, Herrington DM, Tsimikas S, Shapiro MD. Association of Lp(a) (Lipoprotein[a]) and Hypertension in Primary Prevention of Cardiovascular Disease: The MESA. Hypertension. Feb 2023;80(2):352-360. doi:10.1161/HYPERTENSIONAHA.122.20189
9. Mirzai S, Chevli PA, Rikhi R, Shapiro MD. Familial Hypercholesterolemia: From Clinical Suspicion to Novel Treatments. Rev Cardiovasc Med. Nov 2023;24(11):311. doi:10.31083/j.rcm2411311
10. Kiradoh SA, Craven TE, Rangel MO, Nosow LM, Zarrinkhoo E, Menon S, Chevli PA, Islam TM, Thazhatuveetil-Kunhahamed LA. Predicting short-term adverse outcomes in the geriatric population presenting with syncope: a comparison of existing syncope rules and beyond. J Geriatr Cardiol. Jan 28 2023;20(1):11-22. doi:10.26599/1671-5411.2023.01.008
11. Kazibwe R, Singleton MJ, Chevli PA, Kaze AD, Namutebi JH, Shapiro MD, Yeboah J. Association between physical activity and clinical outcomes in high-risk hypertension: Post-hoc analysis of SPRINT. Am J Prev Cardiol. Dec 2023;16:100524. doi:10.1016/j.ajpc.2023.100524
12. Kazibwe R, Singleton MJ, Ahmad MI, Kaze AD, Chevli PA, Namutebi JH, Kasozi RN, Asiimwe DD, Kazibwe J, Shapiro MD, Yeboah J. Association between weight variability, weight change and clinical outcomes in hypertension. Am J Prev Cardiol. Dec 2023;16:100610. doi:10.1016/j.ajpc.2023.100610
13. Kazibwe R, Chevli PA, Evans JK, Allison M, Michos ED, Wood AC, Ding J, Shapiro MD, Mongraw-Chaffin M. Association Between Alcohol Consumption and Ectopic Fat in the Multi-Ethnic Study of Atherosclerosis. J Am Heart Assoc. Sep 19 2023;12(18):e030470. doi:10.1161/JAHA.123.030470
14. Chong B, Jayabaskaran J, Ruban J, Goh R, Chin YH, Kong G, Ng CH, Lin C, Loong S, Muthiah MD, Khoo CM, Shariff E, Chan MY, Lajeunesse-Trempe F, Tchernof A, Chevli P, Mehta A, Mamas MA, Dimitriadis GK, Chew NWS. Epicardial Adipose Tissue Assessed by Computed Tomography and Echocardiography Are Associated With Adverse Cardiovascular Outcomes: A Systematic Review and Meta-Analysis. Circ Cardiovasc Imaging. May 2023;16(5):e015159. doi:10.1161/CIRCIMAGING.122.015159
15. Broni EK, Ogunmoroti O, Osibogun O, Echouffo-Tcheugui JB, Chevli PA, Shapiro MD, Ndumele CE, Michos ED. Ideal Cardiovascular Health and Adipokine Levels: The Multi-Ethnic Study of Atherosclerosis. Endocr Pract. Jun 2023;29(6):456-464. doi:10.1016/j.eprac.2023.03.276
16. Rikhi R, Hammoud A, Ashburn N, Snavely AC, Michos ED, Chevli P, Tsai MY, Herrington D, Shapiro MD. Relationship of low-density lipoprotein-cholesterol and lipoprotein(a) to cardiovascular risk: The Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. Dec 2022;363:102-108. doi:10.1016/j.atherosclerosis.2022.10.004
17. Chevli PA, Mehta A, Allison M, Ding J, Nasir K, Blaha MJ, Blankstein R, Talegawkar SA, Kanaya AM, Shapiro MD, Mongraw-Chaffin M. Relationship of American Heart Association's Life Simple 7, Ectopic Fat, and Insulin Resistance in 5 Racial/Ethnic Groups. J Clin Endocrinol Metab. May 17 2022;107(6):e2394-e2404. doi:10.1210/clinem/dgac102
18. Chevli PA, Islam T, Pokharel Y, Rodriguez F, Virani SS, Blaha MJ, Bertoni AG, Budoff M, Otvos JD, Shapiro MD. Association between remnant lipoprotein cholesterol, high-sensitivity C-reactive protein, and risk of atherosclerotic cardiovascular disease events in the Multi-Ethnic Study of Atherosclerosis (MESA). J Clin Lipidol. Nov-Dec 2022;16(6):870-877. doi:10.1016/j.jacl.2022.09.005
19. Al-Seykal I, Bose A, Chevli PA, Hashmath Z, Sharma N, Mishra AK, Laidlaw D. Role of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in cryoballoon ablation outcomes for paroxysmal atrial fibrillation. World J Cardiol. Oct 26 2022;14(10):537-545. doi:10.4330/wjc.v14.i10.537
20. Chevli PA, Freedman BI, Hsu FC, Xu J, Rudock ME, Ma L, Parks JS, Palmer ND, Shapiro MD. Plasma metabolomic profiling in subclinical atherosclerosis: the Diabetes Heart Study. Cardiovasc Diabetol. Dec 7 2021;20(1):231. doi:10.1186/s12933-021-01419-y
21. Bose A, Hashmath Z, Akella P, Altabaqchali S, Chevli PA, Goyal SB. Idiopathic late coronary sinus lead dislodgement presenting with pulmonary embolism. J Interv Card Electrophysiol. Nov 2021;62(2):441-442. doi:10.1007/s10840-021-01024-9
22. Bose A, Chevli PA, Berberian G, Januszkiewicz J, Ahmad G, Hashmath Z, Mishra AK, Laidlaw D. Presence of a left common pulmonary vein and pulmonary vein anatomical characteristics as predictors of outcome following cryoballoon ablation for paroxysmal atrial fibrillation. J Interv Card Electrophysiol. Nov 2021;62(2):409-417. doi:10.1007/s10840-020-00916-6
23. Aladin AI, Chevli PA, Ahmad MI, Rasool SH, Herrington DM. Alcohol Consumption and Systemic Hypertension (from the Third National Health and Nutrition Examination Survey). Am J Cardiol. Dec 1 2021;160:60-66. doi:10.1016/j.amjcard.2021.08.033
24. Sunkara PR, Islam T, Bose A, Rosenthal GE, Chevli P, Jogu H, Tk LA, Huang CC, Chaudhary D, Beekman D, Dutta A, Menon S, Speiser JL. Impact of structured interdisciplinary bedside rounding on patient outcomes at a large academic health centre. BMJ Qual Saf. Jul 2020;29(7):569-575. doi:10.1136/bmjqs-2019-009936
25. Chevli PA, Hari KJ, Kanaya AM, Talegawkar SA, Needham BL, Herrington D. Association of Alcohol Consumption and Ideal Cardiovascular Health Among South Asians: The Mediators of Atherosclerosis in South Asians Living in America (MASALA) Study. Alcohol Clin Exp Res. Sep 2020;44(9):1825-1833. doi:10.1111/acer.14422
26. Chevli PA, Aladin AI, Kanaya AM, Kandula NR, Malaver D, Herrington DM. Alcohol consumption and subclinical atherosclerosis among South Asians: Findings from the Mediators of Atherosclerosis in South Asians Living in America (MASALA) study. Nutr Metab Cardiovasc Dis. Jan 3 2020;30(1):123-131. doi:10.1016/j.numecd.2019.07.021
27. Chevli PA, Ahmad MI, Hari K, Anees MA, Soliman EZ. Impact of low fasting plasma glucose on mortality in the general population. Diab Vasc Dis Res. May-Jun 2020;17(3):1479164120930599. doi:10.1177/1479164120930599
28. Jogu HR, Arora S, Vaduganathan M, Qamar A, Pandey A, Chevli PA, Pansuriya TH, Ahmad MI, Dutta A, Sunkara PR, Qureshi W, Vasu S, Upadhya B, Bhatt DL, Januzzi JL, Jr., Herrington D. Wake Forest University long-term follow-up of type 2 myocardial infarction: The Wake-Up T2MI Registry. Clin Cardiol. Jun 2019;42(6):592-604. doi:10.1002/clc.23182
29. Anees MA, Ahmad MI, Chevli PA, Li Y, Soliman EZ. Association of vitamin D deficiency with electrocardiographic markers of left atrial abnormalities. Ann Noninvasive Electrocardiol. May 2019;24(3):e12626. doi:10.1111/anec.12626
30. Ahmad MI, Chevli PA, Barot H, Soliman EZ. Interrelationships Between American Heart Association's Life's Simple 7, ECG Silent Myocardial Infarction, and Cardiovascular Mortality. J Am Heart Assoc. Mar 19 2019;8(6):e011648. doi:10.1161/JAHA.118.011648
31. Chevli PA, Ahmad MI, Jogu HR, Dutta A, Anees MA, Sunkara PR, Aladin AI. Electrocardiographic subclinical myocardial injury and alcohol consumption: a cross-sectional analysis of data from the Third National Health and Nutrition Examination Survey. Am J Cardiovasc Dis. 2018;8(5):58-65.
32. Ahmad MI, Chevli PA, Li Y, Soliman EZ. Vitamin D deficiency and electrocardiographic subclinical myocardial injury: Results from National Health and Nutrition Examination Survey-III. Clin Cardiol. Nov 2018;41(11):1468-1473. doi:10.1002/clc.23078
33. Gonzalez-Ibarra F, Chevli P, Schachter L, Kaur M, Eivaz-Mohammadi S, Tashtoush B, Matta J, Syed AK, Marian V. Strongyloidiasis and diffuse alveolar hemorrhage in a patient with systemic lupus erythematosus. Case Rep Med. 2014;2014:278390. doi:10.1155/2014/278390
34. Chevli P, Kelash F, Gadhvi P, Grandhi S, Syed A. Spontaneous coronary artery dissection causing acute coronary syndrome in a young patient without risk factors. J Community Hosp Intern Med Perspect. 2014;4(4)doi:10.3402/jchimp.v4.25104