Alzheimer’s Disease Core Center – Research and Resources

The Wake Forest School of Medicine’s Alzheimer’s Disease Core Center (ADCC) is committed to conducting wide-ranging research on the causes of Alzheimer’s disease, as well as potential methods for treatment and prevention.

We also work to support other researchers who are investigating the disease, providing access to specialized resources that encourage research into the role of metabolic and vascular factors in the causes of Alzheimer’s disease, as well as the development of novel interventions.

Current Research Cores

Clinical Core

Increase knowledge about the role of metabolic and vascular risk factors in promoting the transition from normal aging to mild cognitive impairment, and then to Alzheimer’s or other forms of pathological brain aging such as vascular cognitive impairment (VCI).

Multi-ethnic Study of Atherosclerosis (MESA) Core

Goals of this core resource are to:

  • Study early cardiovascular disease (CVD)
  • Characterize subclinical CVD and progression to clinical CVD
  • Find treatments to disrupt natural history of CVD
  • Improve health

Neuropathology Core

Develop and manage a repository of brain tissue, cerebrospinal fluid, DNA, and blood from Clinical and MESA Core participants of the Wake Forest ADCC using state-of-the-art methods.

Data Management and Data Analytics Core

Goals of this core resource are to:

  • Provide and maintain state-of-the-art resources for data management.
  • Study management and reporting to ensure the highest data quality and study integrity.
  • Increase the efficiency and impact of ADCC research.

Outreach & Recruitment Core/Research Education Component

Goals of this core resource are to:

  • Recruit a diverse group of research participants for ADCC-supported studies.
  • Work with community leaders and organizations to encourage participation of underserved communities in ADCC research and educational activities.
  • Provide education and training for community healthcare professionals and the public about early detection, prevention and treatment of Alzheimer’s Disease.

How to Request Resources from ADCC

Begin the process by selecting a type of resource:

After submitting the form, you’ll receive a confirmation email in one to two business days.

If you have any questions, please contact our administrator Nora Shively.