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Wake Forest University School of Medicine
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  • Wake Forest University School of Medicine
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  • Kimberly J. Nelson, PhD

Kimberly J. Nelson, PhD

  • Instructor, Biochemistry
Kimberly J. Nelson, PhD

Kimberly J. Nelson, PhD

  • Instructor, Biochemistry

Research Interests

  • Peroxiredoxins
  • Cysteine
  • Sulfenic Acids
  • Protein Processing, Post-Translational
  • Hydrogen Peroxide
  • Redox Signaling
  • kinelson@wakehealth.edu
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Education
BS, Furman University, 1997
PhD, Duke University, 2003
Fellowship
Molecular Biology, Wake Forest University School of Medicine, 2008
Memberships
Society for Free Radical Biology and Medicine
American Instit of Chemists
Phi Beta Kappa
Positions
Instructor, Biochemistry
Departments and Affiliations
Biochemistry
Center for Redox Biology and Medicine

Research

  • Publications
  • Differential peroxiredoxin hyperoxidation regulates MAP kinase signaling in human articular chondrocytes. Collins JA, Wood ST, Bolduc JA, Nurmalasari NPD, Chubinskaya S, Poole LB, Furdui CM, Nelson KJ, Loeser RF. Free Radic. Biol. Med. 2019 04; 134:139-152.
  • Peroxiredoxins in Cancer and Response to Radiation Therapies. Forshaw TE, Holmila R, Nelson KJ, Lewis JE, Kemp ML, Tsang AW, Poole LB, Lowther WT, Furdui CM. Antioxidants (Basel). 2019 Jan; 8(1)
  • H2O2 oxidation of cysteine residues in c-Jun N-terminal kinase 2 (JNK2) contributes to redox regulation in human articular chondrocytes. Nelson KJ, Bolduc JA, Wu H, Collins JA, Burke EA, Reisz JA, Klomsiri C, Wood ST, Yammani RR, Poole LB, Furdui CM, Loeser RF. J Biol Chem. 2018 10; 293(42):16376-16389.
  • Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins. Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT. J Biol Chem. 2018 07; 293(30):11901-11912.
  • Endogenous, regulatory cysteine sulfenylation of ERK kinases in response to proliferative signals. Keyes JD, Parsonage D, Yammani RD, Rogers LC, Kesty C, Furdui CM, Nelson KJ, Poole LB. Free Radic. Biol. Med. 2017 11; 112:534-543.
View More Publications

Research Interests

  • Antioxidant Proteins
  • Cysteine
  • Hydrogen Peroxide
  • Peroxiredoxins
  • Protein Processing, Post-Translational
  • Redox Signaling
  • Sulfenic Acids

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