Xiaoyan Iris Leng, MD, PhD
- Associate Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)

Xiaoyan Iris Leng, MD, PhD
- Associate Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)
Research Interests
- Gene Expression
- Aging
- Women's Health
- Biostatistics
- Cognition and Dementia
- Education
- MD, Peking University Health Science Center (PUHSC) (Beijing Medical University), 1995
- MS, Peking University Health Science Center (PUHSC) (Beijing Medical University), 1998
- MS, University of California, Davis (UC Davis), 2001
- PhD, University of California, Davis (UC Davis), 2004
- Memberships
- Institute of Mathematical Statistics
- American Statistical Association
- Positions
- Associate Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)
- Departments and Affiliations
- Biostatistics and Data Science, Public Health Sciences (Winston-Salem)
- Sticht Center for Healthy Aging and Alzheimer’s Prevention (CHAAP)
Research
- Authors' reply to comment on: Effect of protein supplementation on hip bone mineral density, cortical thickness, and bone strength in older adult participants during a caloric restriction and aerobic exercise weight loss intervention: a randomized controlled trial. Stapleton J, Greene KA, Leng X, Lenchik L, Lyles MF, Nicklas BJ, Baker AM, Helgason B, Devane K, Shapses SA, Houston DK, Weaver AA. Osteoporos Int. 2026 Mar;
- Effect of protein supplementation on hip bone mineral density, cortical thickness, and bone strength in older adult participants during a caloric restriction and aerobic exercise weight loss intervention: a randomized controlled trial. Weaver AA, Greene KA, Leng X, Lenchik L, Lyles MF, Nicklas BJ, Baker AM, Helgason B, Stapleton J, Devane K, Shapses SA, Houston DK. Osteoporos Int. 2026 Feb; 37(2):361-372.
- Long-term change in body composition following intentional weight loss and its effect on physical function. Chae K, Leng X, Neiberg RH, Bray GA, Johnson KC, Hill JO, Jakicic JM, Chao AM, Beavers KM, Pownall HJ, Kritchevsky SB, Houston DK. Int J Obes (Lond). 2025 Dec;
- Clonal hematopoiesis of indeterminate potential and the risk of cognitive impairment in the Women's Health Initiative Memory Study. Jakubek YA, Smith AP, Leng XI, Hall ME, Ezzat D, Pershad Y, Collins JM, Uddin MM, Fardo DW, Natarajan P, Bick AG, Kitzman JO, Honigberg MC, Hayden KM, Manson JE, Jaiswal S, Whitsel EA, Reiner AP. Alzheimers Dement. 2025 Oct; 21(10):e70737.
- Multi-site video-based assessment with the NACC UDS-Version 3 battery: Design and participant experience in the V-Cog study. Sachs BC, Latham LA, Isom S, Clark LR, Craft S, Duff K, Espeland MA, Farias ST, Gaussoin SA, Goldstein FC, Hampstead BM, Jayadev S, Jicha GA, Kukull WA, Leng XI, Mechanic-Hamilton D, Neugroschl J, Papp KV, Saykin AJ, Sewell MC, Rapp SR. Alzheimers Dement. 2025 Oct; 21(10):e70842.