“Stress and negative emotional states are often cited as one of the major factors in initiating a substance use disorder. These same feelings can drive cravings and relapse in recovering individuals, highlighting the gripping relationship between addiction and negative affect.”
Dr. Centanni is an assistant professor in the Department of Physiology and Pharmacology at Wake Forest University School of Medicine.
His research focuses on the brain circuits regulating affective behavior and how dysfunction in these circuits drives relapse. The overall aim of the Centanni Lab is to address these questions by taking an innovative, unbiased approach to delineate the complex neuronal control networks governing negative affect associated with stress and alcohol use disorder (AUD). The Centanni Lab uses a variety of techniques, including light sheet microscopy, in vivo and ex vivo electrophysiology and mouse models of stress and alcohol use disorder.
Dr. Centanni received his Doctor of Philosophy at the Medical University of South Carolina.