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  • Wake Forest University School of Medicine
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  • Martha A. Alexander-Miller, PhD
Martha A. Alexander-Miller, PhD
  • Professor, Microbiology and Immunology
Martha A. Alexander-Miller, PhD

Martha A. Alexander-Miller, PhD

  • Professor, Microbiology and Immunology

Research Interests

  • Lymphocyte Activation
  • Dendritic Cells
  • Influenza Virus
  • Vaccines
  • B-Lymphocytes
  • T-Lymphocytes
  • Martha.Alexander-Miller@wakehealth.edu

Research Lab

Alexander Miller Lab - Exploring the regulation of adaptive immunity.

Education Program Involvement

Microbiology and Immunology PhD
Program Research Interest: Immunology, Virology, Bacteriology

Molecular Genetics and Genomics PhD
Program Research Interest: Identification of genetic variants that contribute to complex disease, Gene-environment interactions, Epigenetics, Genetic epidemiology, Bioinformatics

Molecular Medicine and Translational Science PhD
Program Research Interest: Analytical approaches to molecular and cellular synthesis, structure and function, Genetics and gene regulation, Cell communications, Organ systems, Pathophysiology

Education
BS, Butler University, 1988
PhD, Washington University in St. Louis (Wash U), 1993
Fellowship
National Institutes of Health, 1997
Memberships
American Association of Immunologists
Positions
Director, Center for Vaccines at the Extremes of Aging
Dolores G. Evans, PhD Chair in Microbiology and Immunology
Professor, Microbiology and Immunology
Professor, Pediatrics
Departments and Affiliations
Center for Vaccines at the Extremes of Aging
Microbiology and Immunology
Pediatrics
Comprehensive Cancer Center
Center on Diabetes, Obesity, and Metabolism

Research

  • Publications
  • An Analysis of Linker-Dependent Effects on the APC Activation and In Vivo Immunogenicity of an R848-Conjugated Influenza Vaccine. Crofts KF, Page CL, Swedik SM, Holbrook BC, Meyers AK, Zhu X, Parsonage D, Westcott MM, Alexander-Miller MA. Vaccines (Basel). 2023 Jul; 11(7)
  • Maternal influenza vaccination preferentially boosts hemagglutinin stem-specific antibody resulting in efficient transplacental transfer of stem-specific IgG. Zuber MJ, Stamilio DM, Holbrook BC, Snively BM, Jensen ET, Alexander-Miller MA. Int J Gynaecol Obstet. 2023 Jul; 162(1):163-168.
  • Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults. Semelka CT, DeWitt ME, Blevins MW, Holbrook BC, Sanders JW, Alexander-Miller MA. Immun Ageing. 2023 Jan; 20(1):4.
  • Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response. Stirling ER, Terabe M, Wilson AS, Kooshki M, Yamaleyeva LM, Alexander-Miller MA, Zhang W, Miller LD, Triozzi PL, Soto-Pantoja DR. J Immunother Cancer. 2022 Nov; 10(11)
  • TLR agonists induce sustained IgG to hemagglutinin stem and modulate T cells following newborn vaccination. Clemens EA, Holbrook BC, McNeilly B, Kanekiyo M, Graham BS, Alexander-Miller MA. NPJ Vaccines. 2022 Aug; 7(1):102.
View More Publications

Research Interests

  • B-Lymphocytes
  • Dendritic Cells
  • Influenza Virus
  • Lymphocyte Activation
  • Neonatal Immunity
  • T-Lymphocytes
  • Vaccines
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