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  • Wake Forest University School of Medicine
  • Faculty Search
  • Martha A. Alexander-Miller, PhD
Martha A. Alexander-Miller, PhD
  • Professor, Microbiology and Immunology (Winston-Salem)
Martha A. Alexander-Miller, PhD

Martha A. Alexander-Miller, PhD

  • Professor, Microbiology and Immunology (Winston-Salem)

Research Interests

  • Lymphocyte Activation
  • Dendritic Cells
  • Influenza Virus
  • Vaccines
  • B-Lymphocytes
  • T-Lymphocytes
  • Martha.Alexander-Miller@wakehealth.edu

Research Lab

Alexander Miller Lab - Exploring the regulation of adaptive immunity.

Education Program Involvement

Microbiology and Immunology PhD
Program Research Interest: Immunology, Virology, Bacteriology

Molecular Genetics and Genomics PhD
Program Research Interest: Identification of genetic variants that contribute to complex disease, Gene-environment interactions, Epigenetics, Genetic epidemiology, Bioinformatics

Molecular Medicine and Translational Science PhD
Program Research Interest: Analytical approaches to molecular and cellular synthesis, structure and function, Genetics and gene regulation, Cell communications, Organ systems, Pathophysiology

Education
BS, Butler University, 1988
PhD, Washington University in St. Louis (Wash U), 1993
Fellowship
National Institutes of Health, 1997
Memberships
American Association of Immunologists
Positions
Director, Center for Vaccines at the Extremes of Aging
Dolores G. Evans, PhD Chair in Microbiology and Immunology
Professor, Microbiology and Immunology (Winston-Salem)
Professor, Pediatrics (Winston-Salem)
Departments and Affiliations
Center for Vaccines at the Extremes of Aging
Microbiology and Immunology (Winston-Salem)
Pediatrics (Winston-Salem)
Comprehensive Cancer Center
Center for Diabetes, Obesity, and Metabolism (CDOM)

Research

  • Publications
  • Antibody function predicts viral control in newborn monkeys immunised with an influenza virus HA stem nanoparticle. Crofts KF, Holbrook BC, Page CL, Gillespie RA, D'Agostino RB, Sangesland M, Ornelles DA, Kanekiyo M, Alexander-Miller MA. Nat Commun. 2025 Apr; 16(1):3785.
  • Sex-Dependent Effects on Influenza-Specific Antibody Quantity and Neutralizing Activity following Vaccination of Newborn Non-Human Primates Is Determined by Adjuvants. Holbrook BC, Clemens EA, Alexander-Miller MA. Vaccines (Basel). 2024 Apr; 12(4)
  • An Analysis of Linker-Dependent Effects on the APC Activation and In Vivo Immunogenicity of an R848-Conjugated Influenza Vaccine. Crofts KF, Page CL, Swedik SM, Holbrook BC, Meyers AK, Zhu X, Parsonage D, Westcott MM, Alexander-Miller MA. Vaccines (Basel). 2023 Jul; 11(7)
  • Maternal influenza vaccination preferentially boosts hemagglutinin stem-specific antibody resulting in efficient transplacental transfer of stem-specific IgG. Zuber MJ, Stamilio DM, Holbrook BC, Snively BM, Jensen ET, Alexander-Miller MA. Int J Gynaecol Obstet. 2023 Jul; 162(1):163-168.
  • Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults. Semelka CT, DeWitt ME, Blevins MW, Holbrook BC, Sanders JW, Alexander-Miller MA. Immun Ageing. 2023 Jan; 20(1):4.
View More Publications

Research Interests

  • B-Lymphocytes
  • Dendritic Cells
  • Influenza Virus
  • Lymphocyte Activation
  • Neonatal Immunity
  • T-Lymphocytes
  • Vaccines
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