The BioImaging Resource Core (BIRC), part of Wake Forest School of Medicine’s Claude Pepper Older Americans Independence Center (OAIC), provides leadership, scientific expertise and instrumental support in quantitative imaging techniques, including MRI, CT, DXA and PET.

Core Capabilities

The BIRC leads the development and implementation of imaging techniques and protocols to quantify and characterize body composition, particularly skeletal muscle and total, regional and organ-specific adipose tissue, as well as to obtain non-invasive measures of vascular and neuromuscular function.

The core also supports a large image repository to facilitate cross-study comparisons and exploratory analyses of established imaging outcomes as well as the rapid development and validation of new imaging phenotypes. 

Highlighted Core Supported Research

Research Education Component (REC)

  • Kristen Beavers, PhD, “A Pilot Study of the Effects of Exercise Modality During Weight Loss on Bone Mineral Density, Strength and Turnover in Overweight and Obese, Older Adults (CLIP II Bone)”

Pilot/Exploratory Studies (PESC)

  • Paul Laurienti, MD, “Using Baseline Brain Imaging to Predict Success in Weight Loss Interventions in Older Adults”
  • Christina Hugenschmidt, PhD, “Assessing the Relationship of Neurocognitive Dysfunction to Physical Disability and its Improvement with Caloric Restriction and Exercise Training in Older Patients with Heart Failure and Preserved Ejection Fraction (HFpEF)”