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  • Wake Forest University School of Medicine
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  • Rebecca M. Sappington, PhD
Rebecca M. Sappington, PhD
  • Associate Professor, Biochemistry
Rebecca M. Sappington, PhD

Rebecca M. Sappington, PhD

  • Associate Professor, Biochemistry

Research Interests

  • Impact of Neuroinflammation on Development, Aging and Neurodegeneration of the Retina
  • Mechanisms of Neuroinflammation and Their Potential for Therapeutic Targeting
  • Neuron-glia Interactions and Their Roles in CNS Function
  • Development of Nanotechnology for Neuroscience Applications
  • rsapping@wakehealth.edu
Education
BS, Washington College, 2000
MS, University of Rochester School of Medicine and Dentistry, 2023
PhD, University of Rochester School of Medicine and Dentistry, 2024
Fellowship
Vanderbilt University Medical School, 2009
Positions
Associate Professor, Biochemistry
Associate Professor, Ophthalmology
Departments and Affiliations
Biochemistry
Ophthalmology
TrEVR (Translational Eye and Vision Research Center)
Sticht Center for Healthy Aging and Alzheimer’s Prevention

Research

  • Publications
  • Impairment of Membrane Repolarization Accompanies Axon Transport Deficits in Glaucoma. Fischer RA, Risner ML, Roux AL, Wareham LK, Sappington RM. . 2019; 13:1139.
  • Pressure-dependent modulation of inward-rectifying K+ channels: implications for cation homeostasis and K+ dynamics in glaucoma. Fischer RA, Roux AL, Wareham LK, Sappington RM. Am. J. Physiol., Cell Physiol. 2019 08; 317(2):C375-C389.
  • Phenotypes of primary retinal macroglia: Implications for purification and culture conditions. Backstrom JR, Sheng J, Fischer RA, Sappington RM, Rex TS. Exp. Eye Res. 2019 05; 182:85-92.
  • The relationship between the Young's modulus and dry etching rate of polydimethylsiloxane (PDMS). Fitzgerald ML, Tsai S, Bellan LM, Sappington R, Xu Y, Li D. Biomed Microdevices. 2019 03; 21(1):26.
  • Ccl5 Mediates Proper Wiring of Feedforward and Lateral Inhibition Pathways in the Inner Retina. Duncan DS, Weiner RL, Weitlauf C, Risner ML, Roux AL, Sanford ER, Formichella CR, Sappington RM. . 2018; 12:702.
View More Publications

Research Interests

  • Development of Nanotechnology for Neuroscience Applications
  • Impact of Neuroinflammation on Development, Aging and Neurodegeneration of the Retina
  • Mechanisms of Neuroinflammation and Their Potential for Therapeutic Targeting
  • Neuron-glia Interactions and Their Roles in CNS Function
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