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      • Cardiovascular Sciences Center
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      • Wake Forest Institute for Regenerative Medicine (WFIRM)
      • View all Institutes and Centers
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      • Center for Artificial Intelligence Research
      • Center for Healthcare Innovation
      • Maya Angelou Research Center for Healthy Communities (MARCH)
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      • Center for Precision Medicine
      • Public Health Sciences
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      • Wake Forest Clinical and Translational Science Institute
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  • Wake Forest University School of Medicine
  • Faculty Search
  • Nicholas M. Pajewski, PhD
Nicholas M. Pajewski, PhD
  • Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)
Nicholas M. Pajewski, PhD

Nicholas M. Pajewski, PhD

  • Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)

Research Interests

  • Health Status
  • Antihypertensive Agents
  • Hypertension
  • Cognition
  • Electronic Health Records
  • Frailty
  • Email
Education
BS, Loyola University Chicago, 2002
PhD, Medical College of Wisconsin (MCW), 2008
Memberships
Gerontological Association of America
American Geriatrics Society
Positions
Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)
Departments and Affiliations
Biostatistics and Data Science, Public Health Sciences (Winston-Salem)
Center for Healthcare Innovations (CHI)
Sticht Center for Healthy Aging and Alzheimer’s Prevention (CHAAP)

Research

  • Publications
  • The long-term effectiveness of the anti-obesity medication phentermine (LEAP) trial: Rationale, design, and baseline characteristics. Young CB, Rives E, Gudzune KA, Jaeger BC, Simmons CG, White BN, Hooker SA, Horn DB, Young DR, Vesely J, Velazquez A, Price C, Cook SD, Martin-Fernandez K, Inzhakova G, Pajewski NM, Ard JD, Lewis KH. Contemp Clin Trials. 2026 Feb; 161:108219.
  • Effect of Intensive Systolic Blood Pressure Control on Markers of Cerebral Small Vessel Disease by Age. Pruzin JJ, Yau WW, Bress AP, Bardaran H, Chhatwal JP, Tariot PN, Cushman WC, Gupta A, Wright CB, Williamson J, Reboussin DM, Pajewski NM, Nasrallah IM, Kern KC. Hypertension. 2025 Dec; 82(12):2150-2161.
  • Application of the Lancet Commission Criteria for the Diagnosis of Obesity to a Clinical Trials Population: The LEAP Trial. Heeren FAN, Ruddiman KR, Simmons C, White BN, Jaeger BC, Pajewski NM, Hooker SA, Horn DB, Martin-Fernandez K, Gudzune KA, Young CB, Ard J, Lewis KH. Obesity (Silver Spring). 2026 Jan; 34(1):58-64.
  • Frailty and Intensive Blood Pressure Control in ESPRIT: Risk, Benefit, and the Persistent Question of Generalizability. Pajewski NM, Callahan KE, Orkaby AR. J Am Coll Cardiol. 2025 Oct;
  • The Association of Frailty With Post-Hospital Discharge Location and Health Outcomes. Semelka CT, White BN, Callahan KE, Pajewski NM. J Am Geriatr Soc. 2025 Nov; 73(11):3512-3518.
View More Publications

Research Interests

  • Antihypertensive Agents
  • Blood Pressure
  • Cognition
  • Electronic Health Records
  • Frailty
  • Health Status
  • Hypertension
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