William Thomas Harrison, MD

Assistant Professor, Pathology (Winston-Salem)

Research Interests

Alzheimer's Disease
Neurodegenerative Disorders
Seizure Disorders
TDP-43 Encephalopathy
Child Abuse
Creutzfeldt-Jakob Syndrome

Education: MD, Wake Forest University Baptist Medical Center, 2014
Residency: Anatomic and Clinical Pathology, Duke University Medical Center, 2017
Fellowship: Neuropathology, Duke University Medical Center, 2019; Forensic Pathology, Wake Forest University School of Medicine, 2020
Board Certifications: American Board of Pathology, Pathology-Anatomic; American Board of Pathology, Pathology-Forensic; American Board of Pathology, Neuropathology
Positions: Assistant Professor, Pathology (Winston-Salem); Assistant Professor, Gerontology and Geriatrics, Internal Medicine (Winston-Salem); Assistant Professor, Neurology (Winston-Salem)
Departments and Affiliations: Pathology (Winston-Salem); Gerontology and Geriatrics, Internal Medicine (Winston-Salem); Neurology (Winston-Salem); Sticht Center for Healthy Aging and Alzheimer’s Prevention (CHAAP); TrEVR (Translational Eye and Vision Research Center)

Research

Publications

Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers. Fischer DL, Grinberg LT, Ahrendsen JT, Beach TG, Bieniek KF, Castellani RJ, Chkheidze R, Cobos I, Cohen M, Crary JF, Dickson DW, Dugger BN, Dunlop SR, Farrell K, Ghetti B, Haeri M, Harrison W, Head E, Hiniker A, Huang EJ, Huttner A, Jamshidi P, Kapasi A, Keene CD, Kofler J, Latimer CS, McKee AC, Mente K, Miller MB, Montine TJ, Morris M, Murray ME, Nelson PT, Newell KL, Perrin RJ, Ramani B, Reichard RR, Roy S, Schlachetzki JCM, Seeley WW, Serrano GE, Spina S, Teich AF, Wang SJ, Wisniewski T, Lee EB. Alzheimers Dement. 2025 Oct; 21(10):e70734.
Convolutional neural network-derived neurofibrillary tangle classifiers: Investigative tools to identify maturation levels and explore post-translational modifications using laser capture microdissection coupled mass spectrometry. Jimenez Jaramillo C, Nedderman D, Ahat E, McElwee JL, Soper M, Ballard D, Zhang L, Credille KM, Heady G, Hsi ED, Hodsdon ME, Holzer TR, Gruver AM, Harrison WT. J Neuropathol Exp Neurol. 2025 Sep;
MicroRNA cargo in neuron-derived vesicles as peripheral biomarkers of brain insulin dysregulation. Cleary JA, Kumar A, Su Y, Singh S, Hsu FC, Craft S, Harrison W, Keene CD, Howard M, Hayden KM, Espeland MA, Ding J, Deep G. Alzheimers Dement. 2025 Sep; 21(9):e70597.
Alzheimer disease-like neuropathologic changes in a geriatric baboon (Papio hamadryas). Harrison WT, Cline JM, Caudell DL, Huber HF, Shively CA, Register TC, Craft S, Struthers JD. J Vet Sci. 2024 Aug;
Dementia With Lewy Bodies Phenocopy in a Case of RT-QuIC-Negative Creutzfeldt-Jakob Disease: Implications of Functional Anatomy. Wiggins MK, Pharr EP, Wood JL, Craft S, Harrison WT, Bateman JR. J Neuropsychiatry Clin Neurosci. 2024 Jul; :appineuropsych20230205.

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Technology Transfer and Commercialization

Research Focus Areas

Translation to Care

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William Thomas Harrison, MD

Research Interests