Thomas D. DuBose, MD

About Me

Education: MD, University of Alabama School of Medicine, 1970
Residency: University of Alabama Hospitals, 1971; Dallas County Hospital District Parkland Memorial Hospital, 1973
Fellowship: Dallas County Hospital District Parkland Memorial Hospital, 1977
Board Certifications: American Board of Internal Medicine, Internal Medicine; American Board of Internal Medicine, Nephrology
Positions: Professor Emeritus, General Internal Medicine
Departments and Affiliations: General Internal Medicine

The GPCR OGR1 (GPR68) mediates diverse signalling and contraction of airway smooth muscle in response to small reductions in extracellular pH.. Saxena H, Deshpande DA, Tiegs BC, Yan H, Battafarano RJ, Burrows WM, Damera G, Panettieri RA, Dubose TD, An SS, Penn RB. Br. J. Pharmacol. 2012 Jun; 166(3):981-90.
pH-dependent regulation of the a-subunit of H+-K+-ATPase (HKa2).. Codina J, Opyd TS, Powell ZB, Furdui CM, Petrovic S, Penn RB, DuBose TD. Am. J. Physiol. Renal Physiol. 2011 Sep; 301(3):F536-43.
Phosphorylation of S955 at the protein kinase A consensus promotes maturation of the alpha subunit of the colonic H+,K+ -ATPase.. Codina J, Liu J, Bleyer AJ, Penn RB, DuBose TD. J. Am. Soc. Nephrol. 2006 Jul; 17(7):1833-40.
CD63 interacts with the carboxy terminus of the colonic H+-K+-ATPase to decrease [corrected] plasma membrane localization and 86Rb+ uptake.. Codina J, Li J, Dubose TD. Am. J. Physiol., Cell Physiol. 2005 Jun; 288(6):C1279-86.
A carboxy-terminus motif of HKalpha2 is necessary for assembly and function.. Codina J, Li J, Dubose TD. Kidney Int. 2004 Dec; 66(6):2283-92.

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