I am a human molecular geneticist and have experience in monogenic and complex genetic disease research. My research is focused on identifying genetically and epigenetically regulated cellular and molecular mechanisms of insulin resistance, obesity and type 2 diabetes. Determining molecular mechanisms underlying ethnic disparities in these common metabolic diseases is a key area of my research projects funded by the National Institutes of Health and the American Diabetes Association.
As a Principal Investigator of a multidisciplinary research team, I lead studies in human participants and cell culture models and have implemented integrative genomic and systems biology approaches to define genetic and epigenetic regulators of insulin sensitivity in African-Americans and individuals of European ancestry. Knowledge gained through my research projects will help the future development of novel precision medicine approaches to both prevent and treat type 2 diabetes.