David R. Soto Pantoja, PhD

Associate Professor, Cancer Biology

Research Interests

Cancer Immunotherapy
Immunometabolism
Cardio-Oncology

About Me

Educational Program Involvement

Cancer Biology PhD
Program Research Interest: Cellular defense and metabolism, Aberrant signaling pathways in tumor cells, Cell growth and survival, Molecular cancer epidemiology, Gene-environment interactions, Cancer control

Integrative Physiology and Pharmacology PhD
Program Research Interest: Drug and Alcohol Abuse, Cardiovascular Physiology and Hypertension, Regenerative Medicine, Neuro- and Behavioral Pharmacology, Cancer Therapeutics Endocrinology, Diabetes, and Metabolism Lifespan Physiology.

Education: PhD, Wake Forest University, 2008
Fellowship: Cardiovascular Disease, Wake Forest University School of Medicine, 2004; Oncology/Pathology, National Institutes of Health, 2015
Positions: Associate Professor, Cancer Biology; Associate Professor, Hypertension
Departments and Affiliations: Cancer Biology; Hypertension; Comprehensive Cancer Center; Hypertension and Vascular Research Center; Center for Redox Biology and Medicine; Maya Angelou Center for Health Equity; Cardiovascular Sciences Center

Research

Publications

Omega-3 polyunsaturated fatty acid supplementation shifts the gut and breast microbiome to influence inflammation. Cancer Res. Katherine L. Cook; Adam S Wilson; David R Soto-Pantoja; Bruce F. Kimler; Shahid Umar; Carol J. Fabian. . 2022 Feb; 15; 82(4_Suppl):P1-09-03.
In Vitro Cell Impedance Assay to Examine Antigen-Specific T-Cell-Mediated Melanoma Cell Killing to Support Cancer Immunotherapy Drug Discovery. In: Deep, G. (eds) Cancer Biomarkers. Methods in Molecular Biology, vol 2413. Humana, New York, NY. Stirling, E.R., Soto-Pantoja, D.R. . 2022 Jan; 19;
BSCI-17. Targeting SIRPa as a therapeutic strategy for the treatment of breast cancer brain metastasis. Neurooncol Adv. Stirling ER, Bronson SM, Crowe WN, Wilson A, Kooshki M, Zhao D, Triozzi PL, Lesser GJ, Soto-Pantoja DR. . 2021 Aug; 9; v.3(Suppl_3):iii4. doi: 10.1093/noajnl/vdab.
AACR; Cancer Res. Qianqian Song, Elizabeth Forbes, Lance D. Miller, Pierre L. Triozzi, Liang Liu, Wei Zhang and David R. Soto-Pantoja. Single-cell liquid biopsy reveals circulating heterogeneity and converging subpopulations in relation to immunotherapy response in melanoma. 2020 Nov; 1; 80(21_Suppl):Abstract nr PO-127.
AACR;Cancer Res. David R.Soto-Pantoja, Kenysha Y.J. Clear, Adam S. Wilson, Greg Kucera, Edward Levine, Akiko Chiba, Katherine L. Cook. Entero-mammary microbiota signaling axis regulates dietary influences on breast cancer risk. 2020 Apr; 1; 80(8 Suppl):31: PR11.

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Technology Transfer and Commercialization

Research Focus Areas

Translation to Care

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