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  • Wake Forest University School of Medicine
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  • Glenn J. Lesser, MD
Glenn J. Lesser, MD
  • Professor, Hematology and Oncology
Glenn J. Lesser, MD

Glenn J. Lesser, MD

  • Professor, Hematology and Oncology

Research Interests

  • Glioma
  • Glioblastoma
  • Low-Grade Glioma
  • Clinical Trials
  • Neuro-Oncology
  • Brain Tumors
View Patient Care Profile
Education
MD, Pennsylvania State University College of Medicine, 1987
Residency
Wake Forest Baptist Medical Center, 1988
Wake Forest Baptist Medical Center, 1990
Fellowship
Johns Hopkins Hospital, 1994
Board Certifications
American Board of Internal Medicine, Medical Oncology
Memberships
American Society of Clinical Oncology
American Medical Association
Southern Medical Association
American College of Physicians Fellow
Society of Neuro-Oncology
Southern Association For Oncology
North Carolina Medical Association
Positions
Louise McMichael Miracle Professorship in Oncology
Professor, Hematology and Oncology
Professor, Neurosurgery
Professor, Public Health Sciences
Professor, Anesthesiology
Departments and Affiliations
Hematology and Oncology
Neurosurgery
Public Health Sciences
Anesthesiology
Comprehensive Cancer Center
Cardiovascular Sciences Center
Hypertension and Vascular Research Center

Research

  • Publications
  • Clinical Trials
  • The Head and Neck Survivorship Tool (HN-STAR) Trial (WF-1805CD): A protocol for a cluster-randomized, hybrid effectiveness-implementation, pragmatic trial to improve the follow-up care of head and neck cancer survivors. Salz T, Ostroff JS, Nightingale CL, Atkinson TM, Davidson EC, Jinna SR, Kriplani A, Lesser GJ, Lynch KA, Mayer DK, Oeffinger KC, Patil S, Salner AL, Weaver KE. Contemp Clin Trials. 2021 May; 107:106448.
  • Real-Time Positron Emission Tomography Evaluation of Topotecan Brain Kinetics after Ultrasound-Mediated Blood-Brain Barrier Permeability. Molotkov A, Carberry P, Dolan MA, Joseph S, Idumonyi S, Oya S, Castrillon J, Konofagou EE, Doubrovin M, Lesser GJ, Zanderigo F, Mintz A. Pharmaceutics. 2021 Mar; 13(3)
  • A Phase II and Pharmacodynamic Trial of RO4929097 for Patients With Recurrent/Progressive Glioblastoma. Peereboom DM, Ye X, Mikkelsen T, Lesser GJ, Lieberman FS, Robins HI, Ahluwalia MS, Sloan AE, Grossman SA. Neurosurgery. 2021 01; 88(2):246-251.
  • Genomic Profiling of Circulating Tumor DNA From Cerebrospinal Fluid to Guide Clinical Decision Making for Patients With Primary and Metastatic Brain Tumors. Ramkissoon LA, Pegram W, Haberberger J, Danziger N, Lesser G, Strowd R, Dahiya S, Cummings TJ, Bi WL, Abedalthagafi M, Sathyan P, McGregor K, Reddy P, Severson E, Williams E, Lin D, Edgerly C, Huang RSP, Hemmerich A, Creeden J, Brown C, Venstrom J, Hegde P, Ross JS, Alexander BM, Elvin J, Ramkissoon SH. Front Neurol. 2020; 11:544680.
  • Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor. Renfrow JJ, Soike MH, West JL, Ramkissoon SH, Metheny-Barlow L, Mott RT, Kittel CA, D'Agostino RB, Tatter SB, Laxton AW, Frenkel MB, Hawkins GA, Herpai D, Sanders S, Sarkaria JN, Lesser GJ, Debinski W, Strowd RE. Sci Rep. 2020 09; 10(1):15195.
View More Publications
  • A study on the Effectiveness of Four Drugs (Vismodegib, GSK2256098, capivasertib, abemaciclib) Against Meningioma Tumors
  • Finding Therapies that Improve Survival for Patients with Glioblastomas
  • Learning More About Treating Glioma with the Study Drug OKN-007

Research Interests

  • Brain Tumors
  • Clinical Trials
  • Ependymoma
  • Glioblastoma
  • Glioma
  • Low-Grade Glioma
  • Metastatic Brain Tumor
  • Neoplastic Meningitis
  • Neuro-Oncology
  • Primary CNS Lymphoma
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