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  • Glenn J. Lesser, MD

Glenn J. Lesser, MD

  • Professor, Hematology and Oncology
Glenn J. Lesser, MD

Glenn J. Lesser, MD

  • Professor, Hematology and Oncology

Research Interests

  • Glioma
  • Glioblastoma
  • Low-Grade Glioma
  • Clinical Trials
  • Neuro-Oncology
  • Brain Tumors
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Education
BA, Duke University, 1983
MD, Pennsylvania State University College of Medicine, 1987
Residency
Wake Forest Baptist Medical Center, 1988
Wake Forest Baptist Medical Center, 1990
Fellowship
Johns Hopkins Hospital, 1994
Board Certifications
American Board of Internal Medicine, Medical Oncology
Memberships
American Society of Clinical Oncology
American Medical Association
Southern Medical Association
American College of Physicians Fellow
Society of Neuro-Oncology
Southern Association For Oncology
North Carolina Medical Association
Positions
Louise McMichael Miracle Professorship in Oncology
Professor, Hematology and Oncology
Professor, Neurosurgery
Professor, Public Health Sciences
Professor, Anesthesiology
Departments and Affiliations
Hematology and Oncology
Neurosurgery
Public Health Sciences
Anesthesiology
Comprehensive Cancer Center
Hypertension and Vascular Research Center
Cardiovascular Sciences Center

Research

  • Publications
  • Clinical Trials
  • A Randomized Double-Blind Placebo-Controlled Phase II Trial of Dendritic Cell Vaccine ICT-107 in Newly Diagnosed Patients with Glioblastoma. Wen PY, Reardon DA, Armstrong TS, Phuphanich S, Aiken RD, Landolfi JC, Curry WT, Zhu JJ, Glantz M, Peereboom DM, Markert JM, LaRocca R, O'Rourke DM, Fink K, Kim L, Gruber M, Lesser GJ, Pan E, Kesari S, Muzikansky A, Pinilla C, Santos RG, Yu JS. Clin Cancer Res. 2019 10; 25(19):5799-5807.
  • Genome-wide enriched pathway analysis of acute post-radiotherapy pain in breast cancer patients: a prospective cohort study. Lee E, Takita C, Wright JL, Slifer SH, Martin ER, Urbanic JJ, Langefeld CD, Lesser GJ, Shaw EG, Hu JJ. Hum. Genomics. 2019 06; 13(1):28.
  • Treatment of Radiation-Induced Cognitive Decline in Adult Brain Tumor Patients. Cramer CK, Cummings TL, Andrews RN, Strowd R, Rapp SR, Shaw EG, Chan MD, Lesser GJ. Curr Treat Options Oncol. 2019 04; 20(5):42.
  • Safety of pioglitazone during and after radiation therapy in patients with brain tumors: a phase I clinical trial. Cramer CK, Alphonse-Sullivan N, Isom S, Metheny-Barlow LJ, Cummings TL, Page BR, Brown DR, Blackstock AW, Peiffer AM, Strowd RE, Rapp S, Lesser GJ, Shaw EG, Chan MD. J. Cancer Res. Clin. Oncol. 2019 Feb; 145(2):337-344.
  • Mild cognitive impairment in long-term brain tumor survivors following brain irradiation. Cramer CK, McKee N, Case LD, Chan MD, Cummings TL, Lesser GJ, Shaw EG, Rapp SR. J. Neurooncol. 2019 01; 141(1):235-244.
View More Publications
  • A study on the effectiveness of four drugs (Vismodegib, GSK2256098, capivasertib, abemaciclib) against meningioma tumors
  • A study of the drugs Vemurafenib and Cobimetinib in Treating Patients with BRAF Positive V600E Mutation Brain Tumor
  • A study to identify therapies that improve overall survival for patients with Glioblastomas (GBM)

Research Interests

  • Brain Tumors
  • Clinical Trials
  • Ependymoma
  • Glioblastoma
  • Glioma
  • Low-Grade Glioma
  • Metastatic Brain Tumor
  • Neoplastic Meningitis
  • Neuro-Oncology
  • Primary CNS Lymphoma

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