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Wake Forest University School of Medicine
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  • Glenn J. Lesser, MD
Glenn J. Lesser, MD
  • Professor, Hematology and Oncology
Glenn J. Lesser, MD

Glenn J. Lesser, MD

  • Professor, Hematology and Oncology

Research Interests

  • Glioma
  • Glioblastoma
  • Low-Grade Glioma
  • Clinical Trials
  • Neuro-Oncology
  • Brain Tumors
View Patient Care Profile
Education
BA, Duke University, 1983
MD, Pennsylvania State University College of Medicine, 1987
Residency
Wake Forest Baptist Medical Center, 1988
Wake Forest Baptist Medical Center, 1990
Fellowship
Johns Hopkins Hospital, 1994
Board Certifications
American Board of Internal Medicine, Medical Oncology
Memberships
American Society of Clinical Oncology
American Medical Association
Southern Medical Association
American College of Physicians Fellow
Society of Neuro-Oncology
Southern Association For Oncology
North Carolina Medical Association
Positions
Louise McMichael Miracle Professorship in Oncology
Professor, Hematology and Oncology
Professor, Neurosurgery
Professor, Public Health Sciences
Professor, Anesthesiology
Departments and Affiliations
Hematology and Oncology
Neurosurgery
Public Health Sciences
Anesthesiology
Comprehensive Cancer Center
Cardiovascular Sciences Center
Hypertension and Vascular Research Center

Research

  • Publications
  • Clinical Trials
  • Association Between Inflammatory Biomarker C-Reactive Protein and Radiotherapy-Induced Early Adverse Skin Reactions in a Multiracial/Ethnic Breast Cancer Population. Hu JJ, Urbanic JJ, Case LD, Takita C, Wright JL, Brown DR, Langefeld CD, Lively MO, Mitchell SE, Thakrar A, Bryant D, Baglan K, Strasser J, Baez-Diaz L, Lesser GJ, Shaw EG. J. Clin. Oncol. 2018 08; 36(24):2473-2482.
  • Precision Neuro-oncology: the Role of Genomic Testing in the Management of Adult and Pediatric Gliomas. Ramkissoon LA, Britt N, Guevara A, Whitt E, Severson E, Sathyan P, Gay L, Elvin J, Ross JS, Brown C, Stogner-Underwood K, Mott R, Kram D, Strowd R, Lesser GJ, Ramkissoon SH. Curr Treat Options Oncol. 2018 06; 19(8):41.
  • Self-reported adherence and biomarker levels of CoQ10 and alpha-tocopherol. Vitolins MZ, Case LD, Rapp SR, Lively MO, Shaw EG, Naughton MJ, Giguere J, Lesser GJ. . 2018; 12:637-646.
  • Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02. Galanis E, Anderson SK, Miller CR, Sarkaria JN, Jaeckle K, Buckner JC, Ligon KL, Ballman KV, Moore DF, Nebozhyn M, Loboda A, Schiff D, Ahluwalia MS, Lee EQ, Gerstner ER, Lesser GJ, Prados M, Grossman SA, Cerhan J, Giannini C, Wen PY. Neuro-oncology. 2018 03; 20(4):546-556.
  • Truncated Glioma-Associated Oncogene Homolog 1 (tGLI1) Mediates Mesenchymal Glioblastoma via Transcriptional Activation of CD44. Rimkus TK, Carpenter RL, Sirkisoon S, Zhu D, Pasche BC, Chan MD, Lesser GJ, Tatter SB, Watabe K, Debinski W, Lo HW. Cancer Res. 2018 05; 78(10):2589-2600.
View More Publications
  • A study on the effectiveness of four drugs (Vismodegib, GSK2256098, capivasertib, abemaciclib) against meningioma tumors
  • A study of the drugs Vemurafenib and Cobimetinib in Treating Patients with BRAF Positive V600E Mutation Brain Tumor
  • A study to identify therapies that improve overall survival for patients with Glioblastomas (GBM)

Research Interests

  • Brain Tumors
  • Clinical Trials
  • Ependymoma
  • Glioblastoma
  • Glioma
  • Low-Grade Glioma
  • Metastatic Brain Tumor
  • Neoplastic Meningitis
  • Neuro-Oncology
  • Primary CNS Lymphoma
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