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      • Wake Forest Institute for Regenerative Medicine (WFIRM)
      • View all Institutes and Centers
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  • Wake Forest University School of Medicine
  • Faculty Search
  • Bruce Lessey, MD, PhD
Bruce Lessey, MD, PhD
  • Professor, Obstetrics and Gynecology - Reproductive Medicine
Bruce Lessey, MD, PhD

Bruce Lessey, MD, PhD

  • Professor, Obstetrics and Gynecology - Reproductive Medicine
  • blessey@wakehealth.edu
View Patient Care Profile
Education
PhD, Colorado State University, 1980
MD, University of Colorado School of Medicine, 1984
Residency
OB GYN, Duke University School of Medicine, 1988
Fellowship
Reproductive Endocrinology and Infertility, University of Pennsylvania School of Medicine, 1989
Board Certifications
American Board of Obstetrics and Gynecology, Reproductive Endocrinology/Infertility
American Board of Obstetrics and Gynecology, Obstetrics and Gynecology
Memberships
American Society of Reproductive Medicine
Society of Study of Reproduction
Endocrine Society
Positions
Professor, Obstetrics and Gynecology - Reproductive Medicine
Departments and Affiliations
Obstetrics and Gynecology - Reproductive Medicine
Center for Biomedical Informatics
Center for Precision Medicine

Research

  • Publications
  • Clinical Trials
  • Genetic and epigenetic changes in the eutopic endometrium of women with endometriosis: association with decreased endometrial avß3 integrin expression. Joshi NR, Kohan-Ghadr HR, Roqueiro DS, Yoo JY, Fru K, Hestermann E, Yuan L, Ho SM, Jeong JW, Young SL, Lessey BA, Fazleabas AT. Mol Hum Reprod. 2021 May; 27(6)
  • Podocalyxin is a key negative regulator of human endometrial epithelial receptivity for embryo implantation. Paule SG, Heng S, Samarajeewa N, Li Y, Mansilla M, Webb AI, Nebl T, Young SL, Lessey BA, Hull ML, Scelwyn M, Lim R, Vollenhoven B, Rombauts LJ, Nie G. Hum Reprod. 2021 04; 36(5):1353-1366.
  • ARID1A and PGR proteins interact in the endometrium and reveal a positive correlation in endometriosis. Kim HI, Kim TH, Yoo JY, Young SL, Lessey BA, Ku BJ, Jeong JW. Biochem Biophys Res Commun. 2021 04; 550:151-157.
  • Endometrial epithelial ARID1A is critical for uterine gland function in early pregnancy establishment. Marquardt RM, Kim TH, Yoo JY, Teasley HE, Fazleabas AT, Young SL, Lessey BA, Arora R, Jeong JW. FASEB J. 2021 Feb; 35(2):e21209.
  • ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Wilson MR, Reske JJ, Holladay J, Neupane S, Ngo J, Cuthrell N, Wegener M, Rhodes M, Adams M, Sheridan R, Hostetter G, Alotaibi FT, Yong PJ, Anglesio MS, Lessey BA, Leach RE, Teixeira JM, Missmer SA, Fazleabas AT, Chandler RL. Cell Rep. 2020 11; 33(6):108366.
View More Publications
  • Looking at the Connection Between Endometriosis and Pregnancy Loss
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