Stefan Kluzek, MBBD, PhD
- Professor, Orthopaedic Surgery (Winston-Salem)

Stefan Kluzek, MBBD, PhD
- Education
- MD, University of Oxford, 2017
- Residency
- Dept of Medicine/Internal Medicine, Northern Deanery, Health Education England, 2010
- Fellowship
- Sports Medicine Fellowship, Oxford Deanery, Health Education England, 2018
- Positions
- Professor, Orthopaedic Surgery (Winston-Salem)
- Departments and Affiliations
- Orthopaedic Surgery (Winston-Salem)
Research
- Large-scale molecular endotype discovery in synovial fluid reveals osteoarthritis as a single biological continuum. Perry TA, Deng Y, Hulley PA, Maciewicz RA, Mitchelmore J, Larsson S, Gogain J, Brachat S, Struglics A, Appleton CT, Kluzek S, Arden NK, Felson D, Bondi L, Kapoor M, Lohmander LS, Welting TJ, Walsh DA, Valdes AM, Jostins-Dean L, Watt FE, Tom BDM, Vincent TL. Nat Commun. 2026 Jun; 17(1)
- Biomarkers of osteoarthritis progression: collagen-derived markers and their potential translational utility. Kluzek S. Rheumatology (Oxford). 2026 Feb; 65(2)
- Targeting synovial inflammation in knee osteoarthritis: translational insights for diagnosis and therapy. Mobasheri A, Castro-Domínguez F, Gualillo O, Kluzek S, Ruiz SP, Largo R. J Orthop Translat. 2026 Jan; 56:101012.
- Influence of major trauma and lower limb loss on radiographic progression and incidence of knee osteoarthritis and pain: a comparative and predictive analysis from the ADVANCE study. O'Sullivan O, Watson F, Bull AMJ, Schofield S, Coady EC, Boos CJ, Cullinan P, Fear NT, Kluzek S, Bennett AN, Valdes AM. Arthritis Res Ther. 2026 Jan; 28(1):49.
- Severe pincer morphology is associated with incident hip osteoarthritis: prospective individual participant data from 18 935 hips from the World COACH consortium. Riedstra N, Boel F, van Buuren MM, Ahedi H, Arbabi V, Arden NK, Baart SJ, Bierma-Zeinstra SMA, Cicutini F, Cootes T, Crossley KM, Felson DT, Gielis WP, Heerey JJ, Jones G, Kluzek S, Lane NE, Lindner C, Lynch JA, van Meurs J, Mosler AB, Nelson AE, Nevitt MC, Oei EHG, Runhaar J, Tang J, Weinans H, Agricola R. Br J Sports Med. 2026 Jan; 60(2):108-115.