Barry I. Freedman, MD

Professor, Nephrology

Research Interests

Kidney Failure, Chronic
African Americans
Diabetes Mellitus, Type 2
Apolipoproteins
Hypertension

About Me

Education Program Involvement

Molecular Medicine and Translational Science PhD
Program Research Interest: Analytical approaches to molecular and cellular synthesis, structure and function, Genetics and gene regulation, Cell communications, Organ systems, Pathophysiology

Education: MD, State University of New York Brooklyn, 1984
Internship: Eastern Virginia Medical School, 1985
Residency: Eastern Virginia Graduate School of Medicine, 1987
Fellowship: Bowman Gray School of Medicine, 1989
Board Certifications: American Board of Internal Medicine, Internal Medicine; American Board of Internal Medicine, Nephrology
Memberships: American Heart Association; North Carolina Medical Association; American Society of Nephrology; American College of Physicians; International Society of Nephrology; Alpha Omega Alpha Honor Medical Society; Renal Physicians Association; National Kidney Foundation; American Society of Hypertension
Positions: Section Chief, Nephrology; John H. Felts III Chair in Kidney Disease Research
Professor, Nephrology; Professor, Wake Forest Institute for Regenerative Medicine; Professor, Urology
Departments and Affiliations: Nephrology; Wake Forest Institute for Regenerative Medicine; Urology; Hypertension and Vascular Research Center; Sticht Center for Healthy Aging and Alzheimer’s Prevention; Center on Diabetes, Obesity, and Metabolism; Maya Angelou Center for Health Equity; Cardiovascular Sciences Center

Research

Publications

Gene Set Enrichment Analsyes Identiify Pathways Involved in Genetic Risk for Diabetic Retinopathy. Sobrin L, Susarla G, Stanwyck L, Rouhana JM, Li A, Pollack S, Igo RP, Jensen RA, Li X, Ng MCY, Smith AV, Kuo JZ, Taylor KD, Freedman BI, Bowden DW, Penman A, Chen CJ, Craig JE, Adler SG, Chew EY, Cotch MF, Yaspan B, Mitchell P, Wang JJ, Klein BEK, Wong TY, Rotter JI, Burdon KP, Iyengar SK, Segrè AV. Am J Ophthalmol. 2021 Jun; 233:111-123.
Genome-wide association study of vitamin D concentrations and bone mineral density in the African American-Diabetes Heart Study. Palmer ND, Lu L, Register TC, Lenchik L, Carr JJ, Hicks PJ, Smith SC, Xu J, Dimitrov L, Keaton J, Guan M, Ng MCY, Chen YI, Hanley AJ, Engelman CD, Norris JM, Langefeld CD, Wagenknecht LE, Bowden DW, Freedman BI, Divers J. PLoS One. 2021; 16(5):e0251423.
Diagnosis, Education, and Care of Patients with APOL1-Associated Nephropathy: A Delphi Consensus and Systematic Review. Freedman BI, Burke W, Divers J, Eberhard L, Gadegbeku CA, Gbadegesin R, Hall ME, Jones-Smith T, Knight R, Kopp JB, Kovesdy CP, Norris KC, Olabisi OA, Roberts GV, Sedor JR, Blacksher E. J Am Soc Nephrol. 2021 Apr;
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices. Natarajan P, Pampana A, Graham SE, Ruotsalainen SE, Perry JA, de Vries PS, Broome JG, Pirruccello JP, Honigberg MC, Aragam K, Wolford B, Brody JA, Antonacci-Fulton L, Arden M, Aslibekyan S, Assimes TL, Ballantyne CM, Bielak LF, Bis JC, Cade BE, Do R, Doddapaneni H, Emery LS, Hung YJ, Irvin MR, Khan AT, Lange L, Lee J, Lemaitre RN, Martin LW, Metcalf G, Montasser ME, Moon JY, Muzny D, O'Connell JR, Palmer ND, Peralta JM, Peyser PA, Stilp AM, Tsai M, Wang FF, Weeks DE, Yanek LR, Wilson JG, Abecasis G, Arnett DK, Becker LC, Blangero J, Boerwinkle E, Bowden DW, Chang YC, Chen YI, Choi WJ, Correa A, Curran JE, Daly MJ, Dutcher SK, Ellinor PT, Fornage M, Freedman BI, Gabriel S, Germer S, Gibbs RA, He J, Hveem K, Jarvik GP, Kaplan RC, Kardia SLR, Kenny E, Kim RW, Kooperberg C, Laurie CC, Lee S, Lloyd-Jones DM, Loos RJF, Lubitz SA, Mathias RA, Martinez KAV, McGarvey ST, Mitchell BD, Nickerson DA, North KE, Palotie A, Park CJ, Psaty BM, Rao DC, Redline S, Reiner AP, Seo D, Seo JS, Smith AV, Tracy RP, Vasan RS, Kathiresan S, Cupples LA, Rotter JI, Morrison AC, Rich SS, Ripatti S, Willer C, Peloso GM. Nat Commun. 2021 04; 12(1):2182.
APOL1 at 10 years: progress and next steps. Freedman BI, Kopp JB, Sampson MG, Susztak K. Kidney Int. 2021 Jun; 99(6):1296-1302.

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Technology Transfer and Commercialization

Research Focus Areas

Translation to Care

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