Hannah Christine Ainsworth, PhD

Assistant Professor, Biostatistics and Data Science

Hannah Christine Ainsworth, PhD

Assistant Professor, Biostatistics and Data Science

Research Interests

Machine Learning
Complex Diseases
Epigenetics
Bioinformatics
Gene-Environment Interactions
High Performance Computing

Research

Publications

Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes. Ghodke-Puranik Y, Jin Z, Zimmerman KD, Ainsworth HC, Fan W, Jensen MA, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Langefeld CD, Niewold TB. Arthritis Res Ther. 2021 11; 23(1):290.
Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting. Marion MC, Ramos PS, Bachali P, Labonte AC, Zimmerman KD, Ainsworth HC, Heuer SE, Robl RD, Catalina MD, Kelly JA, Howard TD, Lipsky PE, Grammer AC, Langefeld CD. Genes (Basel). 2021 11; 12(12)
Metabolomic architecture of obesity implicates metabolonic lactone sulfate in cardiometabolic disease. Das SK, Ainsworth HC, Dimitrov L, Okut H, Comeau ME, Sharma N, Ng MCY, Norris JM, Chen YI, Wagenknecht LE, Bowden DW, Hsu FC, Taylor KD, Langefeld CD, Palmer ND. Mol Metab. 2021 Sep; 54:101342.
Plasma Mucin-1 (CA15-3) Levels in Autosomal Dominant Tubulointerstitial Kidney Disease due to MUC1 Mutations. Vylet'al P, Kidd K, Ainsworth HC, Springer D, Vrbacká A, Pristoupilová A, Hughey RP, Alper SL, Lennon N, Harrison S, Harden M, Robins V, Taylor A, Martin L, Howard K, Bitar I, Langefeld CD, Barešová V, Hartmannová H, Hodanová K, Zima T, Živná M, Kmoch S, Bleyer AJ. Am J Nephrol. 2021; 52(5):378-387.
Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies. Ainsworth HC, Howard TD, Langefeld CD. Nucleic Acids Res. 2020 11; 48(20):11304-11321.

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Research Interests

Bioinformatics
Complex Diseases
Epigenetics
Gene-Environment Interactions
High Performance Computing
Integrative Omics
Machine Learning
Non-Coding Regulatory Elements
Statistical Genetics
Statistical Methods Development

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Research Focus Areas

Translation to Care

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Hannah Christine Ainsworth, PhD

Hannah Christine Ainsworth, PhD

Research Interests