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      • Wake Forest Institute for Regenerative Medicine (WFIRM)
      • View all Institutes and Centers
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      • Center for Biomedical Informatics
      • Maya Angelou Center for Health Equity
      • Center for Healthcare Innovation
      • Implementation Science
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Wake Forest University School of Medicine
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  • Wake Forest University School of Medicine
  • Faculty Search
  • Hannah Christine Ainsworth, PhD
Hannah Christine Ainsworth, PhD
  • Assistant Professor, Biostatistics and Data Science
Hannah Christine Ainsworth, PhD

Hannah Christine Ainsworth, PhD

  • Assistant Professor, Biostatistics and Data Science

Research Interests

  • Machine Learning
  • Complex Diseases
  • Epigenetics
  • Bioinformatics
  • Gene-Environment Interactions
  • High Performance Computing
Education
BS, Salem College, 2010
BSc, Salem College, 2019
PhD, Wake Forest University, 2019
Positions
Assistant Professor, Biostatistics and Data Science
Departments and Affiliations
Biostatistics and Data Science

Research

  • Publications
  • Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes. Ghodke-Puranik Y, Jin Z, Zimmerman KD, Ainsworth HC, Fan W, Jensen MA, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Langefeld CD, Niewold TB. Arthritis Res Ther. 2021 11; 23(1):290.
  • Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting. Marion MC, Ramos PS, Bachali P, Labonte AC, Zimmerman KD, Ainsworth HC, Heuer SE, Robl RD, Catalina MD, Kelly JA, Howard TD, Lipsky PE, Grammer AC, Langefeld CD. Genes (Basel). 2021 11; 12(12)
  • Metabolomic architecture of obesity implicates metabolonic lactone sulfate in cardiometabolic disease. Das SK, Ainsworth HC, Dimitrov L, Okut H, Comeau ME, Sharma N, Ng MCY, Norris JM, Chen YI, Wagenknecht LE, Bowden DW, Hsu FC, Taylor KD, Langefeld CD, Palmer ND. Mol Metab. 2021 Sep; 54:101342.
  • Plasma Mucin-1 (CA15-3) Levels in Autosomal Dominant Tubulointerstitial Kidney Disease due to MUC1 Mutations. Vylet'al P, Kidd K, Ainsworth HC, Springer D, Vrbacká A, Pristoupilová A, Hughey RP, Alper SL, Lennon N, Harrison S, Harden M, Robins V, Taylor A, Martin L, Howard K, Bitar I, Langefeld CD, Barešová V, Hartmannová H, Hodanová K, Zima T, Živná M, Kmoch S, Bleyer AJ. Am J Nephrol. 2021; 52(5):378-387.
  • Intrinsic DNA topology as a prioritization metric in genomic fine-mapping studies. Ainsworth HC, Howard TD, Langefeld CD. Nucleic Acids Res. 2020 11; 48(20):11304-11321.
View More Publications

Research Interests

  • Bioinformatics
  • Complex Diseases
  • Epigenetics
  • Gene-Environment Interactions
  • High Performance Computing
  • Integrative Omics
  • Machine Learning
  • Non-Coding Regulatory Elements
  • Statistical Genetics
  • Statistical Methods Development
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