Hannah Christine Ainsworth, PhD

Assistant Professor, Biostatistics and Data Science, Public Health Sciences (Winston-Salem)

Research Interests

Machine Learning
Complex Diseases
Epigenetics
Bioinformatics
Gene-Environment Interactions
High Performance Computing

Research

Publications

A Human Airway-on-a-Chip Microphysiological System for Modeling Chlorine Gas Toxicity. Murphy SV, Rajan SAP, Lindert K, Young T, Jiao Y, Zhou Y, Khoury O, McSwain M, Sittadjody S, Hamid Z, Clapp PW, Leach TS, Orr TC, Shankle D, Whitaker E, Sutton K, Albertson SE, Stumpf K, Mutkus L, Simon T, Kulkarni G, Chan J, Lee J, Cox LA, Li G, Campbell C, Olivier M, Puppala S, Reeves TE, Langefeld CD, Ainsworth HC, Ziegler J, Zinnia A, Khan MS, Marini FC, Walker SJ, Shupe TD, Jacobson A, Furdui CM, Bishop AC, Hall AR, Seeds MC, Reeves KD, Atala A. Toxicol Sci. 2025 Dec;
Neutrophil degranulation is increased at seven days after human intracerebral hemorrhage, but not at 72 h, and correlates with decreased miR-3613 and miR-3690. Walsh KB, Marion MC, Li D, Ainsworth HC, Zinnia A, Zhang X, Demel SL, Williamson B, Roh DJ, Campbell R, Denorme F, Woo D, Langefeld CD. BMC Neurol. 2025 Sep; 25(1):388.
Breaking research silos to achieve equitable precision medicine in rheumatology. Ainsworth HC, Baker Frost D, Lim SS, Ramos PS. Nat Rev Rheumatol. 2025 Jan;
Comparative lifespan and healthspan of nonhuman primate species common to biomedical research. Huber HF, Ainsworth HC, Quillen EE, Salmon A, Ross C, Azhar AD, Bales K, Basso MA, Coleman K, Colman R, Darusman HS, Hopkins W, Hotchkiss CE, Jorgensen MJ, Kavanagh K, Li C, Mattison JA, Nathanielsz PW, Saputro S, Scorpio DG, Sosa PM, Vallender EJ, Wang Y, Zeiss CJ, Shively CA, Cox LA. Geroscience. 2024 Nov;
Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques. Deycmar S, Johnson BJ, Ray K, Schaaf GW, Ryan DP, Cullin C, Dozier BL, Ferguson B, Bimber BN, Olson JD, Caudell DL, Whitlow CT, Solingapuram Sai KK, Romero EC, Villinger FJ, Burgos AG, Ainsworth HC, Miller LD, Hawkins GA, Chou JW, Gomes B, Hettich M, Ceppi M, Charo J, Cline JM. J Transl Med. 2024 Mar; 22(1):292.

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Research Interests

Bioinformatics
Complex Diseases
Epigenetics
Gene-Environment Interactions
High Performance Computing
Integrative Omics
Machine Learning
Non-Coding Regulatory Elements
Statistical Genetics
Statistical Methods Development

Technology Transfer and Commercialization

Research Focus Areas

Translation to Care

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Hannah Christine Ainsworth, PhD

Research Interests