Hannah Christine Ainsworth, PhD
- Assistant Professor, Biostatistics and Data Science
Hannah Christine Ainsworth, PhD
Research Interests
- Machine Learning
- Complex Diseases
- Epigenetics
- Bioinformatics
- Gene-Environment Interactions
- High Performance Computing
- Education
- BS, Salem College, 2010
- PhD, Wake Forest University, 2019
- Positions
- Assistant Professor, Biostatistics and Data Science
- Departments and Affiliations
- Biostatistics and Data Science
- Center for Precision Medicine
Research
- Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques. Deycmar S, Johnson BJ, Ray K, Schaaf GW, Ryan DP, Cullin C, Dozier BL, Ferguson B, Bimber BN, Olson JD, Caudell DL, Whitlow CT, Solingapuram Sai KK, Romero EC, Villinger FJ, Burgos AG, Ainsworth HC, Miller LD, Hawkins GA, Chou JW, Gomes B, Hettich M, Ceppi M, Charo J, Cline JM. J Transl Med. 2024 Mar; 22(1):292.
- Comparison of different gene addition strategies to modify placental derived-mesenchymal stromal cells to produce FVIII. Ramamurthy RM, Rodriguez M, Ainsworth HC, Shields J, Meares D, Bishop C, Farland A, Langefeld CD, Atala A, Doering CB, Spencer HT, Porada CD, Almeida-Porada G. Front Immunol. 2022; 13:954984.
- Gut dysbiosis and the clinical spectrum in anti-Ro positive mothers of children with neonatal lupus. Clancy RM, Marion MC, Ainsworth HC, Chang M, Howard TD, Izmirly PM, Masson M, Buyon JP, Langefeld CD. Gut Microbes. 2022; 14(1):2081474.
- Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes. Ghodke-Puranik Y, Jin Z, Zimmerman KD, Ainsworth HC, Fan W, Jensen MA, Dorschner JM, Vsetecka DM, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Langefeld CD, Niewold TB. Arthritis Res Ther. 2021 11; 23(1):290.
- Nucleic Acid-Sensing and Interferon-Inducible Pathways Show Differential Methylation in MZ Twins Discordant for Lupus and Overexpression in Independent Lupus Samples: Implications for Pathogenic Mechanism and Drug Targeting. Marion MC, Ramos PS, Bachali P, Labonte AC, Zimmerman KD, Ainsworth HC, Heuer SE, Robl RD, Catalina MD, Kelly JA, Howard TD, Lipsky PE, Grammer AC, Langefeld CD. Genes (Basel). 2021 11; 12(12)