My lab has several projects that focus on the pathogenesis of complex, chronic diseases such as atherosclerosis (i.e., hardening of the arteries), diabetes, obesity and hepatosteatosis (i.e., fatty liver).

We study the effect of lipid metabolism and inflammation on the development and progression of complex metabolic diseases.

To accomplish the goals of our grant projects, we use an interdisciplinary approach that includes:

  • Transgenic/gene-targeted mouse models of human disease
  • Molecular biology, gene editing
  • Cell biology, biochemistry
  • Mass spectrometry
  • Metabolic phenotyping

We invite you to explore our lab’s research.