I study the identification and genetic mechanisms underlying complex diseases and traits such as Type 2 diabetes, obesity and metabolic syndrome in humans and nonhuman primate models.
Sobha R. Puppala, PhD
- Assistant Professor, Molecular Medicine

Sobha R. Puppala, PhD
Research Interests
- Diabetes Mellitus, Type 2
- Obesity
- Hypertension
- Maternal Nutritional Physiological Phenomena
- Positions
- Assistant Professor, Molecular Medicine
- Departments and Affiliations
- Molecular Medicine
- Center for Precision Medicine
Research
- Analysis of serum changes in response to a high fat high cholesterol diet challenge reveals metabolic biomarkers of atherosclerosis. Misra BB, Puppala SR, Comuzzie AG, Mahaney MC, VandeBerg JL, Olivier M, Cox LA. PLoS ONE. 2019; 14(4):e0214487.
- Primate fetal hepatic responses to maternal obesity: epigenetic signalling pathways and lipid accumulation. Puppala S, Li C, Glenn JP, Saxena R, Gawrieh S, Quinn A, Palarczyk J, Dick EJ, Nathanielsz PW, Cox LA. J. Physiol. (Lond.). 2018 12; 596(23):5823-5837.
- Genetic and environmental (physical fitness and sedentary activity) interaction effects on cardiometabolic risk factors in Mexican American children and adolescents. Arya R, Farook VS, Fowler SP, Puppala S, Chittoor G, Resendez RG, Mummidi S, Vanamala J, Almasy L, Curran JE, Comuzzie AG, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Diego VP. Genet Epidemiol. 2018 06; 42(4):378-393.
- Genetics of serum carotenoid concentrations and their correlation with obesity-related traits in Mexican American children. Farook VS, Reddivari L, Mummidi S, Puppala S, Arya R, Lopez-Alvarenga JC, Fowler SP, Chittoor G, Resendez RG, Kumar BM, Comuzzie AG, Curran JE, Lehman DM, Jenkinson CP, Lynch JL, DeFronzo RA, Blangero J, Hale DE, Duggirala R, Vanamala JK. Am. J. Clin. Nutr. 2017 Jul; 106(1):52-58.
- GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans. Chittoor G, Kent JW, Almeida M, Puppala S, Farook VS, Cole SA, Haack K, Göring HH, MacCluer JW, Curran JE, Carless MA, Johnson MP, Moses EK, Almasy L, Mahaney MC, Lehman DM, Duggirala R, Comuzzie AG, Blangero J, Voruganti VS. BMC Genomics. 2016 Apr; 17:276.