Fred W. Perrino, PhD

About Me

Education: BS, Ohio State University, 1979; PhD, University of Cincinnati, 1986
Fellowship: University of Cincinnati, 1985; University of Washington School, 1989
Memberships: New York Academy of Sciences; American Association of Cancer Research; American Society of Biochemistry & Molecular Biology; American Society of Microbiology
Positions: Professor, Biochemistry
Departments and Affiliations: Biochemistry

Identification of Inhibitors of the dNTP Triphosphohydrolase SAMHD1 Using a Novel and Direct High-Throughput Assay.. Mauney CH, Perrino FW, Hollis T. Biochemistry. 2018 Nov; 57(47):6624-6636.
TREX1 D18N mice fail to process erythroblast DNA resulting in inflammation and dysfunctional erythropoiesis.. Rego SL, Harvey S, Simpson SR, Hemphill WO, McIver ZA, Grayson JM, Perrino FW. Autoimmunity. 2018 Nov; :1-12.
Solid-State Nanopore Analysis of Diverse DNA Base Modifications Using a Modular Enzymatic Labeling Process.. Wang F, Zahid OK, Swain BE, Parsonage D, Hollis T, Harvey S, Perrino FW, Kohli RM, Taylor EW, Hall AR. Nano Lett. 2017 11; 17(11):7110-7116.
The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch.. Mauney CH, Rogers LC, Harris RS, Daniel LW, Devarie-Baez NO, Wu H, Furdui CM, Poole LB, Perrino FW, Hollis T. Antioxid. Redox Signal. 2017 Dec; 27(16):1317-1331.
DNase-active TREX1 frame-shift mutants induce serologic autoimmunity in mice.. Sakai T, Miyazaki T, Shin DM, Kim YS, Qi CF, Fariss R, Munasinghe J, Wang H, Kovalchuk AL, Kothari PH, Fermaintt CS, Atkinson JP, Perrino FW, Yan N, Morse HC. J. Autoimmun. 2017 Jul; 81:13-23.

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