Replacing a Human Ear

The current solution for replacing a human ear is to surgically implant an ear-shaped device under the skin. Because the device is a foreign material, however, there can be problems with infection and protrusion from the skin, which can require additional surgery. Researchers at Wake Forest Institute for Regenerative Medicine (WFIRM) are working toward a better solution.

Research Significance

Various groups of investigators are targeting the 3D printing of ear parts due to the need of improved technologies for patients with hearing loss.This work is also being combined with the use of strategies that can enhance inner ear hair cell regeneration, which is important for both hearing and balance.

Research Approach and Goals

WFIRM is 3D printing external ear structures, consisting of the pinna and ear lobe, that benefit hearing and are important cosmetically. The pinna or ear shell is the shell-like part of the external ear and is made of cartilage and skin. The pinna directs sound waves from the outside into the external auditory canal (ear canal).

Research Highlights and Innovation

Institute scientists are working to cover traditional surgical implants, as well as porous molds developed in the laboratory, with a patient's own cartilage cells before implantation. The body then acts as "nature's incubator" allowing cartilage tissues to form.

As part of this feasibility research, WFIRM scientists will be assessing the biocompatibility and long-term durability of the implant for use in patient populations.v

The current solution for replacing a human ear is to surgically implant an ear-shaped device under the skin. Because the device is a foreign material, however, there can be problems with infection and protrusion from the skin, which can require additional surgery. Researchers at Wake Forest Institute for Regenerative Medicine (WFIRM) are working toward a better solution.

Applications WFIRM

Scientists at the Wake Forest Institute for Regenerative Medicine are working to cover traditional surgical implants, as well as porous molds developed in the laboratory, with a patient's own cartilage cells before implantation.