Using Noninvasive Brainwave Technology to Treat PTSD Symptoms

Stories and Features

HIRREMMirroring a person’s brainwaves to treat symptoms of PTSD may sound like something from a science-fiction novel, but it’s not. A pilot study conducted at Wake Forest Baptist Medical Center showed that the noninvasive technology significantly reduced symptoms of post-traumatic stress in military personnel. The study is published in the Dec. 22 online edition of the journal Military Medical Research.

“Ongoing symptoms of post-traumatic stress, whether clinically diagnosed or not, are a pervasive problem in the military,” said the study’s principal investigator, Charles H. Tegeler, MD, professor of neurology at Wake Forest School of Medicine, a part of Wake Forest Baptist.

“Medications are often used to help control specific symptoms but can produce side effects. Other treatments may not be well tolerated, and few show a benefit for the associated sleep disturbance. Additional noninvasive, non-drug therapies are needed.”

According to the U.S. Department of Veterans Affairs, approximately 31 percent of Vietnam veterans, 10 percent of Gulf War (Desert Storm) veterans and 11 percent of veterans of the war in Afghanistan experience PTSD. Symptoms can include insomnia, poor concentration, sadness, re-experiencing traumatic events, irritability or hyper-alertness, as well as diminished autonomic cardiovascular regulation.

The neurotechnology used in this study – High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM) – is a noninvasive, closed-loop, acoustic stimulation approach, in which computer software algorithms translate specific brain frequencies into audible tones in real time.

Figuratively speaking, this provides a chance for the brain to listen to itself, Tegeler said. Likely through resonance between brain frequencies and the acoustic stimulation, the brain is supported to make self-adjustments toward improved balance and reduced hyperarousal, with no conscious, cognitive activity required. The net effect is to support the brain to reset stress response patterns that have been rewired by repetitive traumatic events, physical or nonphysical.

“We observed reductions in post-traumatic symptoms, including insomnia, depressive mood and anxiety that were durable through six months after the use of HIRREM, but additional research is needed to confirm these initial findings,” he said.

“This study is also the first to report improvement in heart rate variability and baroreflex sensitivity – physiological responses to stress – after the use of an intervention for service members or veterans with ongoing symptoms of post-traumatic stress.”

Limitations of the study include the small number of participants and the absence of a control group. It also was an open-label project, meaning that both researchers and participants knew what treatment was being administered.

HIRREM is a registered trademark of Brain State Technologies based in Scottsdale, Arizona, and has been licensed to Wake Forest Baptist for collaborative research since 2011.