J. Mark Cline, DVM, PhD
- Professor, Pathology - Comparative Medicine
J. Mark Cline, DVM, PhD
Research Interests
- Breast Cancer
- Dietary and Hormonal Effects on Cancer Risk
- Cancer Immunotherapy
- Comparative Pathology
- Nonhuman Primates
- Radiation Injury: Immune Recovery and Late Effects
- Education
- BS, North Carolina State University, 1982
- DVM, North Carolina State University, 1986
- PhD, North Carolina State University, 1992
- Residency
- Pathology - Anatomic, New York State College Veterinary, 1988
- Memberships
- Society for Toxicologic Pathology
- American Coll of Veterinary Pathologists
- American Association of Cancer Research
- DVM Foundation for the Advancement of Veterinary and Comparative Pathology
- American Veterinary Medical Association
- Radiation Research Society
- American Association of Medical Colleges (Business)
- Positions
- Professor, Pathology - Comparative Medicine
- Professor, Radiation Oncology
- Professor, Clinical and Translational Science Institute
- Professor, Wake Forest Institute for Regenerative Medicine
- Departments and Affiliations
- Pathology - Comparative Medicine
- Radiation Oncology
- Clinical and Translational Science Institute
- Wake Forest Institute for Regenerative Medicine
- Hypertension and Vascular Research Center
- Comprehensive Cancer Center
- Center for Vaccines at the Extremes of Aging
- Cardiovascular Sciences Center
- Center for Precision Medicine
Research
- Post-Irradiation Treatment with a Superoxide Dismutase Mimic, MnTnHex-2-PyP5+, Mitigates Radiation Injury in the Lungs of Non-Human Primates after Whole-Thorax Exposure to Ionizing Radiation. Cline JM, Dugan G, Bourland JD, Perry DL, Stitzel JD, Weaver AA, Jiang C, Tovmasyan A, Owzar K, Spasojevic I, Batinic-Haberle I, Vujaskovic Z. . 2018 Mar; 7(3)
- Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells. Ghandhi SA, Turner HC, Shuryak I, Dugan GO, Bourland JD, Olson JD, Tooze JA, Morton SR, Batinic-Haberle I, Cline JM, Amundson SA. PLoS ONE. 2018; 13(1):e0191402.
- Changes in microvascular density differentiate metabolic health outcomes in monkeys with prior radiation exposure and subsequent skeletal muscle ECM remodeling. Fanning KM, Pfisterer B, Davis AT, Presley TD, Williams IM, Wasserman DH, Cline JM, Kavanagh K. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2017 Sep; 313(3):R290-R297.
- Cerebrovascular Remodeling and Neuroinflammation is a Late Effect of Radiation-Induced Brain Injury in Non-Human Primates. Andrews RN, Metheny-Barlow LJ, Peiffer AM, Hanbury DB, Tooze JA, Bourland JD, Hampson RE, Deadwyler SA, Cline JM. Radiat. Res. 2017 05; 187(5):599-611.
- Long-Term Cognitive Functioning in Single-Dose Total-Body Gamma-Irradiated Rhesus Monkeys ( Macaca mulatta ). Hanbury DB, Peiffer AM, Dugan G, Andrews RN, Cline JM. Radiat. Res. 2016 Nov; 186(5):447-454.