Wake Forest University School of Medicine will anchor the Howard R. Levine Center for Education in the heart of The Pearl, and will be joined by Carolinas College of Health Sciences, and connect with Wake Forest University’s School of Professional Studies and School of Business and other educational opportunities. This is the first, four-year medical school in Charlotte. While third and fourth-year students have rotated in Charlotte for their clinical clerkships for years, the campus will now expand and seat its first four-year class in 2025.

On January 17, 2023, construction of the long-awaited second campus of the School of Medicine near Uptown Charlotte began with an official groundbreaking.